20 research outputs found
Venture Capital and Business Angels and the Creation of Innovative Firms in Poland
The article also points out that conditions fostering further development of the described types of entrepreneurship and innovation financing and a dynamic environment generating innovative capacity should be created.W artykule zasygnalizowano również potrzebę kreowania uwarunkowań sprzyjających rozwojowi opisanych form finansowania przedsiębiorczości, innowacyjności i dynamicznego otoczenia generującego zdolności innowacyjne
Unknown risks and the collapse of human civilisation: A review of the AI-related scenarios
Science and technology have experienced a great transition, a development that has shaped all of humanity. As progress continues, we face major global threats and unknown existential risks even though humankind remains uncertain about how likely unknown risks are to occur. This paper addresses five straightforward questions: (1) How can we best understand the concept of (existential) risks within the broader framework of known and unknown? (2) Are unknown risks worth focusing on? (3) What is already known and unknown about AI-related risks? (4) Can a super-AI collapse our civilisation? Furthermore, (5) how can we deal with AI-related risks that are currently unknown? The paper argues that it is of high priority that more research work be done in the area of ‘unknown risks’ in order to manage potentially unsafe scientific innovations. The paper finally concludes with the plea for public funding, planning and raising a general awareness that the far-reaching future is in our own hands
Anti-inflammatory activity of extracts of root bark of Securidaca longipedunculata fres (polygalaceae)
The effect of extract and fractions of the root bark of Securidaca longipedunculata Fres (Polygalaceae) on acute inflammation was evaluated. Solvent extraction yielded the crude methanol extract (ME) while solvent–guided extraction yielded a petroleum ether fraction (PF) and methanol fraction (MF). The extract and fractions inhibited topical edema induced by xylene in the mouse ear. In the systemic edema of the rat paw, the methanol extract (ME) and methanol fraction (MF) significantly (P PF > ME. Phytochemical tests showed that ME and MF tested positive for carbohydrates, reducing sugars, glycosides, flavonoids, terpenoids, sterols and saponins while PF gave positive reaction for resins only.Acute toxicity test for ME in mice established an i.p and p.o LD50 of 11 and 282 mg/kg respectively.
Keywords: Securidaca longipedunculata, root bark, acute inflammation, systemic edemaAfrican Journal of Traditional, Complementary and Alternative Medicines Vol. 3(1) 2006: 54-6
Research Paper - ANTI-INFLAMMATORY ACTIVITY OF EXTRACTS OF ROOT BARK OF SECURIDACA LONGIPEDUNCULATA FRES (POLYGALACEAE)
The effect of extract and fractions of the root bark of Securidaca
longipedunculata Fres (Polygalaceae) on acute inflammation was
evaluated. Solvent extraction yielded the crude methanol extract (ME)
while solvent guided extraction yielded a petroleum ether fraction (PF)
and methanol fraction (MF). The extract and fractions inhibited topical
edema induced by xylene in the mouse ear. In the systemic edema of the
rat paw, the methanol extract (ME) and methanol fraction (MF)
significantly (P<0.05) suppressed the development of paw edema
induced by egg albumin in rats while the petroleum ether fraction (PF)
was devoid of such activity.Ulcerogenic assay in rats indicated that
the extract and fractions exhibited varying degrees of gastric
irritation in rats in the order of magnitude: MF > PF > ME.
Phytochemical tests showed that ME and MF tested positive for
carbohydrates, reducing sugars, glycosides, flavonoids, terpenoids,
sterols and saponins while PF gave positive reaction for resins
only.Acute toxicity test for ME in mice established an i.p and p.o LD50
of 11 and 282 mg/kg respectively
Investigation on Monodora tenuifolia seed oil (Annonaceae)
No Abstract.Bio-Research Vol. 3(2) 2005: 56-5
Evaluation of the Antiulcer Properties of Pseudocedrela kotschyi Stem Bark Extract
Aqueous stem bark extract of Pseudocedrela kotschyi, Harms (Meliaceae) was investigated for antiulcer activity. The extract neither contracted nor relaxed the isolated guinea pig ileum. It however, inhibited the contraction evoked by acetylcholine and histamine in a doserelated manner. Gastrointestinal motility in mice was significantly (
<span style="font-size: 20.0pt;mso-bidi-font-size:14.0pt;font-family:"Times New Roman","serif"">Evaluation of methanolic extract of <i>Ficus platyphylla </i>on <span style="font-size: 20.0pt;mso-bidi-font-size:14.0pt;font-family:"Times New Roman","serif"">gastrointestinal activity </span></span>
63-67<span style="font-size:
15.0pt;mso-bidi-font-size:9.0pt;font-family:" times="" new="" roman","serif""="">Methanolic
extract of <span style="font-size:14.5pt;mso-bidi-font-size:8.5pt;
font-family:" times="" new="" roman","serif""="">Ficus platyphylla was
tested on isolated rabbit jejunum, rat duodenum and gastrointestinal motility
in mice. The extract showed a biphasic effect on isolated smooth muscle. Lower
concentration or extract caused contraction, while higher concentrations
produced relaxation. The contractile phase was attenuated by atropine, while relaxant
phase attenuated histamine induced contraction or guinea pig ileum. The extract
also exhibited a dose-dependent inhibition of gastrointestinal motility. Acute
toxicity test in mice established LD<span style="font-size:12.0pt;
mso-bidi-font-size:6.0pt;font-family:" arial","sans-serif""="">50
value
(ip) or the extract to be 2000 mg/kg.
<span style="font-size:15.0pt;mso-bidi-font-size:9.0pt;
line-height:115%;font-family:" times="" new="" roman","serif""="">Preliminary
phytochemical screening or the extract gave positive test for flavonoids,
tannins and saponins.
</span