726 research outputs found
Childhood injury after a parental cancer diagnosis
A parental cancer diagnosis is psychologically straining for the whole family. We
investigated whether a parental cancer diagnosis is associated with a higher-than-expected risk of
injury among children by using a Swedish nationwide register-based cohort study. Compared to
children without parental cancer, children with parental cancer had a higher rate of hospital contact
for injury during the first year after parental cancer diagnosis (hazard ratio [HR] = 1.27, 95%
confidence interval [CI] = 1.22-1.33), especially when the parent had a comorbid psychiatric
disorder after cancer diagnosis (HR = 1.41, 95% CI = 1.08-1.85). The rate increment declined during
the second and third year after parental cancer diagnosis (HR = 1.10, 95% CI = 1.07-1.14) and
became null afterwards (HR = 1.01, 95% CI = 0.99-1.03). Children with parental cancer also had a
higher rate of repeated injuries than the other children (HR = 1.13, 95% CI = 1.12-1.15). Given the
high rate of injury among children in the general population, our findings may have important
public health implications.NonePublishe
The "Clubs against Drugs" program in Stockholm, Sweden: two cross-sectional surveys examining drug use among staff at licensed premises
<p>Abstract</p> <p>Background</p> <p>The objective of this study is to examine self-reported drug use among staff at licensed premises, types of drugs used, attitudes towards drugs, and observed drug use among guests. Results are presented from two measurement points (in 2001 and 2007/08). This study was carried out within the framework of the "Clubs against Drugs" program, which is a community-based multi-component intervention targeting licensed premises in Stockholm, Sweden.</p> <p>Methods</p> <p>Two cross-sectional surveys were conducted, the first in 2001 and the second in 2007/08. Staff at licensed premises attending server training were asked to participate in the anonymous survey. A survey was administered in a classroom setting and consisted of four sections: 1) demographics, 2) respondents' own drug use experience, 3) respondents' attitudes towards drug use, and 4) observed drug use among guests at licensed premises.</p> <p>Results</p> <p>Data were collected from 446 staff in 2001 and 677 staff in 2007/08. The four most commonly used drugs among staff were cannabis, cocaine, amphetamine, and ecstasy. The highest rates of drug use were reported by staff in the two youngest age groups, i.e., those younger than 25 and those between the ages of 25 and 29. In 2007/08 staff reported significantly lower rates of drug use than staff in 2001. Last year drug use for the sample in 2007/08 was 19% compared to 27% for the 2001 sample. While drug-using staff compared to non drug-using staff reported more observations of drug use among guests, they were less inclined to intervene. Overall, staff reported restrictive attitudes towards drugs.</p> <p>Conclusions</p> <p>The prevalence of life-time and last year drug use among staff at licensed premises is high compared to the general population in Sweden. Lower rates of self-reported drug use among staff were reported in 2007/08. The results of this study highlight that staff at licensed premises represent an important target population in club drug prevention programs.</p
Dust in Brown Dwarfs IV. Dust formation and driven turbulence on mesoscopic scales
Dust formation in brown dwarf atmospheres is studied by utilising a model for
driven turbulence in the mesoscopic scale regime. We apply a pseudo-spectral
method where waves are created and superimposed within a limited wavenumber
interval. The turbulent kinetic energy distribution follows the Kolmogoroff
spectrum which is assumed to be the most likely value. Such superimposed,
stochastic waves may occur in a convectively active environment. They cause
nucleation fronts and nucleation events and thereby initiate the dust formation
process which continues until all condensible material is consumed. Small
disturbances are found to have a large impact on the dust forming system. An
initially dust-hostile region, which may originally be optically thin, becomes
optically thick in a patchy way showing considerable variations in the dust
properties during the formation process. The dust appears in lanes and curls as
a result of the interaction with waves, i.e. turbulence, which form larger and
larger structures with time. Aiming on a physical understanding of the
variability of brown dwarfs, related to structure formation in substellar
atmospheres, we work out first necessary criteria for small-scale closure
models to be applied in macroscopic simulations of dust forming astrophysical
systems.Comment: A&A accepted, 20 page
Directed geometrical worm algorithm applied to the quantum rotor model
We discuss the implementation of a directed geometrical worm algorithm for
the study of quantum link-current models. In this algorithm Monte Carlo updates
are made through the biased reptation of a worm through the lattice. A directed
algorithm is an algorithm where, during the construction of the worm, the
probability for erasing the immediately preceding part of the worm, when adding
a new part,is minimal. We introduce a simple numerical procedure for minimizing
this probability. The procedure only depends on appropriately defined local
probabilities and should be generally applicable. Furthermore we show how
correlation functions, C(r,tau) can be straightforwardly obtained from the
probability of a worm to reach a site (r,tau) away from its starting point
independent of whether or not a directed version of the algorithm is used.
Detailed analytical proofs of the validity of the Monte Carlo algorithms are
presented for both the directed and un-directed geometrical worm algorithms.
Results for auto-correlation times and Green functions are presented for the
quantum rotor model.Comment: 11 pages, 9 figures, v2 : Additional results and data calculated at
an incorrect chemical potential replaced. Conclusions unchange
Childhood injury after a parental cancer diagnosis
A parental cancer diagnosis is psychologically straining for the whole family. We investigated whether a parental cancer diagnosis is associated with a higher-than-expected risk of injury among children by using a Swedish nationwide register-based cohort study. Compared to children without parental cancer, children with parental cancer had a higher rate of hospital contact for injury during the first year after parental cancer diagnosis (hazard ratio [HR] = 1.27, 95% confidence interval [CI] = 1.22-1.33), especially when the parent had a comorbid psychiatric disorder after cancer diagnosis (HR = 1.41, 95% CI = 1.08-1.85). The rate increment declined during the second and third year after parental cancer diagnosis (HR = 1.10, 95% CI = 1.07-1.14) and became null afterwards (HR = 1.01, 95% CI = 0.99-1.03). Children with parental cancer also had a higher rate of repeated injuries than the other children (HR = 1.13, 95% CI = 1.12-1.15). Given the high rate of injury among children in the general population, our findings may have important public health implications
Effects of Non-Aerobic Maximal Effort Exercise on Fatigue in Deconditioned Men and Women with Multiple Sclerosis
Multiple Sclerosis (MS) is a neurodegenerative disease of unknown etiology affecting women more frequently than men. Mental and physical fatigue complaints are often the most disabling symptoms for an MS patient. Both are multifactorial, potentially exacerbated by aerobic exercise, may prevent sustained physical functioning, and significantly interfere with activities of daily living1. A multi-center study was designed to investigate the effects of non-aerobic maximal effort exercise (MEE) for deconditioned persons with MS, with the expectation of minimizing fatigue. The IsoPUMP (Neuromuscular Engineering; Nashville, TN), is a specialized exercise and strength-sensing machine, designed to allow individuals to safely perform and record their non-aerobic MEE sessions. The Modified Fatigue Impact Scale (MFIS) and Multiple Sclerosis Functional Composite (MSFC) are common, accepted methods used to measure fatigue and function. The MFIS is a 21-item questionnaire which assesses the subjectsâ perception of physical, cognitive, and psychosocial aspects of fatigue over a four-week period2. Each of the 21 items are scored on a scale from 0 (never) to 4 (almost always), and the total MFIS score is calculated by summing the circled number for each item. Total scores can range from 0 to 84; higher scores indicating a greater impact of fatigue on the person. The MFIS has three distinct subscales: (1) physical, (2) cognitive, and (3) psychosocial. These subscales can be scored independently by summing the questions that pertain to each subscale2. The MFIS physical subscale score can range from 0 â 36 and the MFIS cognitive subscale score can range from 0 â 40. The MSFC combines clinical measures used to assess lower limb function (Timed 25-Foot Walk [25-FW]), upper limb function (9-Hole Peg Test [9-HPT]), and cognition (Paced Auditory Serial Addition Test [PASAT-3â])3. The 25-FW is a quantitative measure of lower extremity function. The 9-HPT is a quantitative measure of arm and hand function where a subject inserts and then removes 9 pegs from a board, using one hand at a time. The time is recorded for each hand with the dominant hand trial first and the non-dominant hand trial second. The final score is recorded as the mean time for both hands. The PASAT-3â is a measure of cognitive function, specifically assessing auditory information processing speed, short-term memory, flexibility, and calculation ability. Cognitive dysfunction affects half of all MS patients; slowing ability to reason, concentrate, and recall5. In this test subjects listen to a series of 61 spoken numbers separated by 3 seconds and must add each number to the prior number. Their final PASAT-3â score is the number of correct additions in the series, with 60 reflecting a perfect score. The MSFC is then evaluated by creating Z-scores for each component, which compare each outcome with the average outcome of the study population. The three Z-scores are then averaged to create an overall composite score (the MSFC score) which represents change over time for that population of MS subjects3
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