539 research outputs found
Autler-Townes splitting in two-color photoassociation of 6Li
We report on high-resolution two-color photoassociation spectroscopy in the
triplet system of magneto-optically trapped 6Li. The absolute transition
frequencies have been measured. Strong optical coupling of the bound molecular
states has been observed as Autler-Townes splitting in the photoassociation
signal. The spontaneous bound-bound transition rate is determined and the
molecule formation rate is estimated. The observed lineshapes are in good
agreement with the theoretical model.Comment: 5 pages, 4 figures, accepted for publication in Phys. Rev. A (Rapid
Communication
Saturation in heteronuclear photoassociation of 6Li7Li
We report heteronuclear photoassociation spectroscopy in a mixture of
magneto-optically trapped 6Li and 7Li. Hyperfine resolved spectra of the
vibrational level v=83 of the singlet state have been taken up to intensities
of 1000 W/cm^2. Saturation of the photoassociation rate has been observed for
two hyperfine transitions, which can be shown to be due to saturation of the
rate coefficient near the unitarity limit. Saturation intensities on the order
of 40 W/cm^2 can be determined.Comment: 5 pages, 3 figures, to appear in Phys. Rev. A (Rapid Communication
Pattern formation in 2-frequency forced parametric waves
We present an experimental investigation of superlattice patterns generated
on the surface of a fluid via parametric forcing with 2 commensurate
frequencies. The spatio-temporal behavior of 4 qualitatively different types of
superlattice patterns is described in detail. These states are generated via a
number of different 3--wave resonant interactions. They occur either as
symmetry--breaking bifurcations of hexagonal patterns composed of a single
unstable mode or via nonlinear interactions between the two primary unstable
modes generated by the two forcing frequencies. A coherent picture of these
states together with the phase space in which they appear is presented. In
addition, we describe a number of new superlattice states generated by 4--wave
interactions that arise when symmetry constraints rule out 3--wave resonances.Comment: The paper contains 34 pages and 53 figures and provides an extensive
review of both the theoretical and experimental work peformed in this syste
Circumstellar disks and planets. Science cases for next-generation optical/infrared long-baseline interferometers
We present a review of the interplay between the evolution of circumstellar
disks and the formation of planets, both from the perspective of theoretical
models and dedicated observations. Based on this, we identify and discuss
fundamental questions concerning the formation and evolution of circumstellar
disks and planets which can be addressed in the near future with optical and
infrared long-baseline interferometers. Furthermore, the importance of
complementary observations with long-baseline (sub)millimeter interferometers
and high-sensitivity infrared observatories is outlined.Comment: 83 pages; Accepted for publication in "Astronomy and Astrophysics
Review"; The final publication is available at http://www.springerlink.co
Prognostic significance of IDH-1 and MGMT in patients with glioblastoma: One step forward, and one step back?
A group of 160 patients with primary glioblastoma treated with radiotherapy and temozolomide was analyzed for the impact of O6-methly-guanly-methyl-transferase (MGMT)-promoter methylation as well as isocitrate dehydrogenase (IDH)1-mutational status. Unexpectedly, overall survival or progression-free survival were not longer in the group with methylated MGMT-promoter as compared to patients without that methylation. IDH-1 mutations were significantly associated with increased overall survival
Dre-miR-2188 Targets Nrp2a and Mediates Proper Intersegmental Vessel Development in Zebrafish Embryos
BACKGROUND: MicroRNAs (miRNAs) are a class of small RNAs that are implicated in the control of eukaryotic gene expression by binding to the 3'UTR of target mRNAs. Several algorithms have been developed for miRNA target prediction however, experimental validation is still essential for the correct identification of miRNA targets. We have recently predicted that Neuropilin2a (Nrp2a), a vascular endothelial growth factor receptor which is essential for normal developmental angiogenesis in zebrafish, is a dre-miR-2188 target. METHODOLOGY: Here we show that dre-miR-2188 targets the 3'-untranslated region (3'UTR) of Nrp2a mRNA and is implicated in proper intersegmental vessel development in vivo. Over expression of miR-2188 in zebrafish embryos down regulates Nrp2a expression and results in intersegmental vessel disruption, while its silencing increases Nrp2a expression and intersegmental vessel sprouting. An in vivo GFP sensor assay based on a fusion between the GFP coding region and the Nrp2a 3'UTR confirms that miR-2188 binds to the 3'UTR of Nrp2a and inhibits protein translation. CONCLUSIONS: We demonstrate that miR-2188 targets Nrp2a and affects intersegmental vessel development in zebrafish embryos
The patriotism of gentlemen with red hair: European Jews and the liberal state, 1789–1939
European Jewish history from 1789–1939 supports the view that construction of national identities even in secular liberal states was determined not only by modern considerations alone but also by ancient patterns of thought, behaviour and prejudice. Emancipation stimulated unprecedented patriotism, especially in wartime, as Jews strove to prove loyalty to their countries of citizenship. During World War I, even Zionists split along national lines, as did families and friends. Jewish patriotism was interchangeable with nationalism inasmuch as Jews identified themselves with national cultures. Although emancipation implied acceptance and an end to anti-Jewish prejudice in the modern liberal state, the kaleidoscopic variety of Jewish patriotism throughout Europe inadvertently undermined the idea of national identity and often provoked anti-Semitism. Even as loyal citizens of separate states, the Jews, however scattered, disunited and diverse, were made to feel, often unwillingly, that they were one people in exile
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