Fast high-efficiency integrated waveguide photodetectors using novel hybrid vertical/butt coupling geometry

We report a novel coupling geometry for integrated waveguide photodetectors−a hybrid vertical coupling/butt coupling scheme that allows the integration of fast, efficient, photodetectors with conventional double heterostructure waveguides. It can be employed to yield a planar, or pseudo-planar, surface that supports further levels of integration. The approach is demonstrated with a 25-µm-long p-i-n detector integrated with an InP/InGaAsP/InP waveguide, which displays a high (~90%) efficiency and large (~15 GHz) bandwidth. This is the fastest high-efficiency integrated waveguide photodetector reported to date

Kinematic modeling of disk galaxies III. The warped "Spindle" NGC 2685

This is the third of a series of papers in which the structure and kinematics of disk galaxies is studied. Employing direct tilted-ring fits to the data cube as introduced in Paper I, we perform an analysis of the "Spindle" galaxy NGC 2685, previously regarded as two-ringed polar ring galaxy. Deep HI and optical (i'-band) observations are presented. The HI observations strongly suggest that the gaseous structure of NGC 2685 does not consist of two separate mutually inclined regions, but forms a coherent, extremely warped disk, the appearance of two rings being due to projection effects. By comparing the HI total-intensity maps with the optical image we demonstrate that at large radii a faint stellar disk is well aligned with the outer HI disk. The shape of the dust-lanes obscuring the NE part of the inner stellar body indicates that also at smaller radii NGC 2685 possesses a disk containing gas, dust, and stars in which the various constituents are aligned. At smaller radii, this disk is kinematically decoupled from the central stellar body. Hence, in the region of the bright, central stellar body, NGC 2685 appears to consist of two disks that share a common centre, but have different orientation: a bright stellar lenticular body apparently devoid of dust and gas, and a heavily warped low-surface brightness disk containing stars, gas and dust. The low-surface-brightness disk changes its orientation gradually and at large radii assumes the orientation of the central stellar S0 disk. Since, according to our analysis, the intrinsic orientation of the low-surface-brightness disk changes through 70 degrees, the gaseous disk is coherent, and is at no radius orientated perpendicularly with respect to the central stellar body, NGC 2685 is likely not a classical polar-ring galaxy.Comment: 26 pages, 14 figures, 6 tables, accepted for publication in Astronomy & Astrophysics. For a high-resolution version see http://www.astron.nl/~jozsa/publications

The star formation rate history in the FORS Deep and GOODS South Fields

We measure the star formation rate (SFR) as a function of redshift z up to z \~4.5, based on B, I and (I+B) selected galaxy catalogues from the FORS Deep Field (FDF) and the K-selected catalogue from the GOODS-South field. Distances are computed from spectroscopically calibrated photometric redshifts accurate to (Delta_z / (z_spec+1)) ~0.03 for the FDF and ~0.056 for the GOODS-South field. The SFRs are derived from the luminosities at 1500 Angstroem. We find that the total SFR estimates derived from B, I and I+B catalogues agree very well (\lsim 0.1 dex) while the SFR from the K catalogue is lower by ~0.2 dex. We show that the latter is solely due to the lower star-forming activity of K-selected intermediate and low luminosity (L<L_*) galaxies. The SFR of bright (L>L_*) galaxies is independent of the selection band, i.e. the same for B, I, (I+B), and K-selected galaxy samples. At all redshifts, luminous galaxies (L>L_*) contribute only ~1/3 to the total SFR. There is no evidence for significant cosmic variance between the SFRs in the FDF and GOODs-South field, ~0.1 dex, consistent with theoretical expectations. The SFRs derived here are in excellent agreement with previous measurements provided we assume the same faint-end slope of the luminosity function as previous works (alpha ~ -1.6). However, our deep FDF data indicate a shallower slope of alpha=-1.07, implying a SFR lower by ~0.3 dex. We find the SFR to be roughly constant up to z ~4 and then to decline slowly beyond, if dust extinctions are assumed to be constant with redshift.Comment: 6 pages, 2 figures, Accepted for publication in ApJ

The Cluster Mass Function from Weak Gravitational Lensing

We present the first measurement of the mass function of galaxy clusters based directly on cluster masses derived from observations of weak gravitational lensing. To investigate the degree of sample incompleteness resulting from the X-ray based selection of the target clusters, we use a sample of 50 clusters with weak lensing mass measurements to empirically determine the relation between lensing mass and X-ray luminosity and the scatter about this relation. We use a complete, volume-limited sub-sample of 35 X-ray luminous clusters of galaxies at 0.15<z<0.3 to constrain the abundance of very massive (M >~ 10^15/h M_sun) clusters. From this, we constrain sigma_8(Omega_m/0.3)^{0.37} = 0.67^{+0.04}_{-0.05} (68% confidence limits), agreeing well with constraints from the 3-year WMAP CMB measurements and estimates of cluster abundances based on X-ray observations, but somewhat lower than constraints from ``cosmic shear'' weak lensing measurements in random fields.Comment: 10 pages, 3 figures. Accepted for publication in Ap

First Results On Shear-Selected Clusters From the Deep Lens Survey: Optical Imaging, Spectroscopy, and X-ray Followup

We present the first sample of galaxy clusters selected on the basis of their weak gravitational lensing shear. The shear induced by a cluster is a function of its mass profile and its redshift relative to the background galaxies being sheared; in contrast to more traditional methods of selecting clusters, shear selection does not depend on the cluster's star formation history, baryon content, or dynamical state. Because mass is the property of clusters which provides constraints on cosmological parameters, the dependence on these other parameters could induce potentially important biases in traditionally-selected samples. Comparison of a shear-selected sample with optically and X-ray selected samples is therefore of great importance. Here we present the first step toward a new shear-selected sample: the selection of cluster candidates from the first 8.6 deg$^2$ of the 20 deg$^2$ Deep Lens Survey (DLS), and tabulation of their basic properties such as redshifts and optical and X-ray counterparts.Comment: v2 as published in ApJ, 45 pages, 18 figures. Biggest change from v1 is addition of a figure showing the 1-point distribution of pixels in the mass maps and control "mass maps" using the non-tangential component of shear, demonstrating that all candidate peaks are higher than any peak seen in the control map

Klotho Lacks a Vitamin D Independent Physiological Role in Glucose Homeostasis, Bone Turnover, and Steady-State PTH Secretion In Vivo

Apart from its function as co-receptor for fibroblast growth factor-23 (FGF23), Klotho is thought to regulate insulin signaling, intracellular oxidative stress, and parathyroid hormone (PTH) secretion in an FGF23 independent fashion. Here, we crossed Klotho deficient (Kl−/−) mice with vitamin D receptor (VDR) mutant mice to examine further vitamin D independent functions of Klotho. All mice were fed a rescue diet enriched with calcium, phosphorus, and lactose to prevent hyperparathyroidism in VDR mutants, and were killed at 4 weeks of age after double fluorochrome labeling. Kl−/− mice displayed hypercalcemia, hyperphosphatemia, dwarfism, organ atrophy, azotemia, pulmonary emphysema, and osteomalacia. In addition, glucose and insulin tolerance tests revealed hypoglycemia and profoundly increased peripheral insulin sensitivity in Kl−/− mice. Compound mutants were normocalcemic and normophosphatemic, did not show premature aging or organ atrophy, and were phenocopies of VDR mutant mice in terms of body weight, bone mineral density, bone metabolism, serum calcium, serum phosphate, serum PTH, gene expression in parathyroid glands, as well as urinary calcium and phosphate excretion. Furthermore, ablation of vitamin D signaling in double mutants completely normalized glucose and insulin tolerance, indicating that Klotho has no vitamin D independent effects on insulin signaling. Histomorphometry of pancreas islets showed similar beta cell volume per body weight in all groups of animals. In conclusion, our findings cast doubt on a physiologically relevant vitamin D and Fgf23 independent function of Klotho in the regulation of glucose metabolism, bone turnover, and steady-state PTH secretion in vivo

Der Umzug der Menschheit: Die transformative Kraft der Städte

Die Wucht der derzeitigen Urbanisierungsdynamik und ihre Auswirkungen sind so groß, dass sich weltweit Städte, Stadtgesellschaften, Regierungen und Internationale Organisationen diesem Trend stellen müssen. Ein „Weiter so wie bisher“, würde ohne gestaltende Urbanisierungspolitik zu einer nicht-nachhaltigen Welt-Städte-Gesellschaft führen. Nur wenn Städte und Stadtgesellschaften ausreichend handlungsfähig werden, können sie ihre Kraft für eine nachhaltige Entwicklung entfalten: In den Städten wird sich entscheiden, ob die Große Transformation zur Nachhaltigkeit gelingt. In diesem Buch werden die Erfolgsbedingungen dafür diskutiert

Humanity on the move: Unlocking the transformative power of cities

The momentum of urbanization and its impacts are so massive that we must face up to this trend. In view of the existing cognitive, technical, economic and institutional path dependencies, a policy of business as usual – i.e. an unstructured, quasi-automatic urbanization – would lead to a non-sustainable ‘world cities society’. Only if cities and urban societies are sufficiently empowered can they make use of the opportunities for sustainability and successfully follow the urban transformation pathways. The success or failure of the Great Transformation will be decided in the cities. The WBGU discusses the relevant conditions for the success of this transformation in this report

Hen 2-104: A close-up look at the Southern Crab

The kinematics, shaping, density distribution, expansion distance, and ionized mass of the nebula Hen 2-104, and the nature of its symbiotic Mira are investigated. A combination of multi-epoch HST images and VLT integral field high-resolution spectroscopy is used to study the nebular dynamics both along the line of sight and in the plane of the sky. These observations allow us to construct a 3-D spatio-kinematical model of the nebula, which together with the measurement of its apparent expansion in the plane of the sky over a period of 4 years, provides the expansion parallax for the nebula. The integral field data featuring the [S{\sc ii}] $\lambda\lambda$671.7,673.1 emission line doublet provide us with a density map of the inner lobes of the nebula, which together with the distance estimation allow us to estimate its ionized mass. We find densities ranging from n$_e$=500 to 1000 cm$^{-3}$ in the inner lobes and from 300 to 500cm$^{-3}$ in the outer lobes. We determine an expansion parallax distance of 3.3$\pm$0.9 kpc to Hen 2-104, implying an unexpectedly large ionized mass for the nebula of the order of one tenth of a solar mass.Comment: 11 pages, 12 figures, accepted for publication in A&

Impact of antimicrobial drug restrictions on doctors' behaviors

Background/aim: Broad-spectrum antibiotics have become available for use only with the approval of infectious disease specialists (IDSs) since 2003 in Turkey. This study aimed to analyze the tendencies of doctors who are not disease specialists (non-IDSs) towards the restriction of antibiotics.Materials and methods: A questionnaire form was prepared, which included a total of 22 questions about the impact of antibiotic restriction (AR) policy, the role of IDSs in the restriction, and the perception of this change in antibiotic consumption. The questionnaire was completed by each participating physician.Results: A total of 1906 specialists from 20 cities in Turkey participated in the study. Of those who participated, 1271 (67.5%) had 5 years of occupational experience in their branch expressed that they followed the antibiotic guidelines more strictly than the JSs (P < 0.05) and 755 of physicians (88%) and 720 of surgeons (84.6%) thought that the AR policy was necessary and useful (P < 0.05).Conclusion: This study indicated that the AR policy was supported by most of the specialists. Physicians supported this restriction policy more so than surgeons did