58 research outputs found
Carcass Compound Materials Base on Fluoropolymer for Tissue Engineering in Orthopedics
In this work new type of composite materials for application as coatings for intramedullary implants in the field of orthopaedics and traumatology is offered. Method is based on ability of fluoropolymers to act as biologically inert binding agent and ability of fine-dyspersated hydroxyapatite powders to act as biologically active filling agent providing osteoinduction and osteoconduction processes. Results of investigations of adhesion, elastic and morphometric characteristics of offered composite were presented; chemical composition was determined. Estimation of toxicological properties, locally irritant action and hemolytic activity of offered composites was done according to GOST R ISO 10993. In vivo tests were carried out; it was shown that offered composites didn’t cause any negative tissue reactions and stimulated osteogenesis processes in ectopic bone formation test. Key words: Carcass Compound Materials; fluoropolymers; orthopaedi
Fabrication and properties of L-arginine-doped PCL electrospun composite scaffolds
The article describes fabrication and properties of composite fibrous
scaffolds obtained by electrospinning of the solution of
poly({\epsilon}-caprolactone) and arginine in common solvent. The influence of
arginine content on structure, mechanical, surface and biological properties of
the scaffolds was investigated. It was found that with an increase of arginine
concentration diameter of the scaffold fibers was reduced, which was
accompanied by an increase of scaffold strength and Young modulus. It was
demonstrated that porosity and water contact angle of the scaffold are
independent from arginine content. The best cell adhesion and viability was
shown on scaffolds with arginine concentration from 0.5 to 1 % wt
Modification of the zirconia ceramics by different calcium phosphate coatings:comparative study
The aim of this study was to characterize different calcium phosphate
coatings and evaluate in vitro cell response of these materials to ceramics
implants. The physical and chemical properties of calcium phosphate coatings
formed by RF-magnetron sputtering of calcium phosphate tribasic,
hydroxyapatite, calcium phosphate monobasic, calcium phosphate dibasic
dihydrate and calcium pyrophosphate powders were characterized. Cell adhesion
and cell viability were examined on calcium phosphate coatings using
mesenchymal stem cells. The results of cytotoxicity measurements of the calcium
phosphate coatings revealed that only the coating obtained by RF-magnetron
sputtering of the calcium phosphate dibasic dihydrate and calcium phosphate
tribasic powders possessed lower cell viability than the zirconia substrate.
The coating formed by sputtering of the calcium phosphate tribasic powder
demonstrated more cells adhered onto its surface compared with other calcium
phosphate coatings
Energetics of Propellant Options for High-Power Hall Thrusters
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76265/1/AIAA-16376-173.pd
Influence of magnesium and strontium substitutions in the structure of hydroxyapatite lattice on the deposition rate and properties of the CaP coatings formed via RF-sputtering of the powder targets
This work is dedicated to studying of the properties of the calcium phosphate (CaP) coatings deposited on Ti substrates by radio-frequency magnetron sputtering (RFMS) of three hydroxyapatite-based powder targets: pure hydroxyapatite (HA), Mg-substituted HA (Mg-HA, Mg = 0.93 ± 0.13 at.%) and Sr-substituted HA (Sr-HA, Sr ∼ 0.47 at.%). The influence of ionic substitutions in the structure of the sputtered targets on the surface morphology, physicochemical properties of the coatings and their wettability were studied. It is revealed that Mg and Sr ionic substitutions in the crystal lattice of HA at these concentrations don't affect deposition rate, however, it influences morphology, wettability and elemental and phase composition of deposited coatings
Influence of the high-power ion-beam irradiation of a hydroxyapatite target on the properties of formed calcium phosphate coatings
The physical-mechanical of properties of biocompatible calcium phosphate coatings deposited onto titanium and silicon substrates from erosion materials, which are generated by irradiating hydroxyapatite (synthetic and natural) targets by means of the high-power pulsed ion beam of a Temp-4 accelerator, are investigated. A calculation technique for predicting the rate and energy efficiency of deposition using pulsed ion beams is proposed. Their characteristics are analyzed as applied to the formation of calcium phosphate coatings
Modification of the zirconia ceramics by different calcium phosphate coatings:comparative study
The aim of this study was to characterize different calcium phosphate
coatings and evaluate in vitro cell response of these materials to ceramics
implants. The physical and chemical properties of calcium phosphate coatings
formed by RF-magnetron sputtering of calcium phosphate tribasic,
hydroxyapatite, calcium phosphate monobasic, calcium phosphate dibasic
dihydrate and calcium pyrophosphate powders were characterized. Cell adhesion
and cell viability were examined on calcium phosphate coatings using
mesenchymal stem cells. The results of cytotoxicity measurements of the calcium
phosphate coatings revealed that only the coating obtained by RF-magnetron
sputtering of the calcium phosphate dibasic dihydrate and calcium phosphate
tribasic powders possessed lower cell viability than the zirconia substrate.
The coating formed by sputtering of the calcium phosphate tribasic powder
demonstrated more cells adhered onto its surface compared with other calcium
phosphate coatings
Experimental Evaluation of Russian Anode Layer Thrusters
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76973/1/AIAA-1994-3010-800.pd
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