The aim of this study was to characterize different calcium phosphate
coatings and evaluate in vitro cell response of these materials to ceramics
implants. The physical and chemical properties of calcium phosphate coatings
formed by RF-magnetron sputtering of calcium phosphate tribasic,
hydroxyapatite, calcium phosphate monobasic, calcium phosphate dibasic
dihydrate and calcium pyrophosphate powders were characterized. Cell adhesion
and cell viability were examined on calcium phosphate coatings using
mesenchymal stem cells. The results of cytotoxicity measurements of the calcium
phosphate coatings revealed that only the coating obtained by RF-magnetron
sputtering of the calcium phosphate dibasic dihydrate and calcium phosphate
tribasic powders possessed lower cell viability than the zirconia substrate.
The coating formed by sputtering of the calcium phosphate tribasic powder
demonstrated more cells adhered onto its surface compared with other calcium
phosphate coatings
