32 research outputs found

    The Importance of Building a Relationship Between Lecturers and Students for Student Satisfaction with Remote Learning

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    This article aimed to determine the significance of student-lecturer relationships in the context of remote learning to answer the following question: What is the relationship between student-lecturer relationships and student satisfaction with remote learning, feedback, the assessment process, lecturers’ digital competencies and students’ competencies related to remote learning? To achieve this aim, an online survey was conducted on a sample of 206 students from Milenium University in Gniezno, Poland (return rate approximately 42%) in the spring of 2022. The data were analysed through the application of mediation analysis using IBM SPSS Statistics and the Jamovi software. The main finding of the study is that the student-lecturer relationship is crucial for ensuring students’ satisfaction with remote learning. This paper contributes to the literature by explaining the potential impact of other factors on the student-lecturer relationship variable.This article aimed to determine the significance of student-lecturer relationships in the context of remote learning to answer the following question: What is the relationship between student-lecturer relationships and student satisfaction with remote learning, feedback, the assessment process, lecturers’ digital competencies and students’ competencies related to remote learning? To achieve this aim, an online survey was conducted on a sample of 206 students from Milenium University in Gniezno, Poland (return rate approximately 42%) in the spring of 2022. The data were analysed through the application of mediation analysis using IBM SPSS Statistics and the Jamovi software. The main finding of the study is that the student-lecturer relationship is crucial for ensuring students’ satisfaction with remote learning. This paper contributes to the literature by explaining the potential impact of other factors on the student-lecturer relationship variable

    Physicochemical and bilogical characterization of soils from the vicinity of the Arctowski Polish Antarctic Station

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    Soil samples collected in 2006 from 4 different sites (Puchalski Hill and a moraine below this hill, an elephant seal colony and a penguin rookery) in the vicinity of Arctowski Polish Antarctic Station at King George Island were characterized in terms of physicochemical properties (pH, humidity, concentration of selected inorganic and organic substances), microbial colonization and the overall activity of selected enzymes (differentglycosidases and esterases). Activity of the latter enzymes was assayed by p-nitrophenyl and 4-methylumbelliferone derivatives of fatty acids (by spectrophotometric and fluorimetric method, respectively). The highest lipolytic activity was found in soils from the elephant seal colony and penguin rookery

    Genetic diversity of the Plasmodium falciparum GTP-cyclohydrolase 1, dihydrofolate reductase and dihydropteroate synthetase genes reveals new insights into sulfadoxine-pyrimethamine antimalarial drug resistance.

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    Plasmodium falciparum parasites resistant to antimalarial treatments have hindered malaria disease control. Sulfadoxine-pyrimethamine (SP) was used globally as a first-line treatment for malaria after wide-spread resistance to chloroquine emerged and, although replaced by artemisinin combinations, is currently used as intermittent preventive treatment of malaria in pregnancy and in young children as part of seasonal malaria chemoprophylaxis in sub-Saharan Africa. The emergence of SP-resistant parasites has been predominantly driven by cumulative build-up of mutations in the dihydrofolate reductase (pfdhfr) and dihydropteroate synthetase (pfdhps) genes, but additional amplifications in the folate pathway rate-limiting pfgch1 gene and promoter, have recently been described. However, the genetic make-up and prevalence of those amplifications is not fully understood. We analyse the whole genome sequence data of 4,134 P. falciparum isolates across 29 malaria endemic countries, and reveal that the pfgch1 gene and promoter amplifications have at least ten different forms, occurring collectively in 23% and 34% in Southeast Asian and African isolates, respectively. Amplifications are more likely to be present in isolates with a greater accumulation of pfdhfr and pfdhps substitutions (median of 1 additional mutations; P<0.00001), and there was evidence that the frequency of pfgch1 variants may be increasing in some African populations, presumably under the pressure of SP for chemoprophylaxis and anti-folate containing antibiotics used for the treatment of bacterial infections. The selection of P. falciparum with pfgch1 amplifications may enhance the fitness of parasites with pfdhfr and pfdhps substitutions, potentially threatening the efficacy of this regimen for prevention of malaria in vulnerable groups. Our work describes new pfgch1 amplifications that can be used to inform the surveillance of SP drug resistance, its prophylactic use, and future experimental work to understand functional mechanisms

    Population genetic analysis of Plasmodium knowlesi reveals differential selection and exchange events between Borneo and Peninsular sub-populations

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    Funding: A.T. was funded by a Newton Institutional Links Grant (British Council, no. 261868591). S.C. was funded by BloomsburySET and Medical Research Council UK grants (MR/M01360X/1, MR/R025576/1, MR/R020973/1, and MR/X005895/1). T.G.C. was funded by the Medical Research Council UK (Grant nos. MR/M01360X/1, MR/N010469/1, MR/R025576/1, MR/R020973/1, and MR/X005895/1).The zoonotic Plasmodium knowlesi parasite is a growing public health concern in Southeast Asia, especially in Malaysia, where elimination of P. falciparum and P. vivax malaria has been the focus of control efforts. Understanding of the genetic diversity of P. knowlesi parasites can provide insights into its evolution, population structure, diagnostics, transmission dynamics, and the emergence of drug resistance. Previous work has revealed that P. knowlesi fall into three main sub-populations distinguished by a combination of geographical location and macaque host (Macaca fascicularis and M. nemestrina). It has been shown that Malaysian Borneo groups display profound heterogeneity with long regions of high or low divergence resulting in mosaic patterns between sub-populations, with some evidence of chromosomal-segment exchanges. However, the genetic structure of non-Borneo sub-populations is less clear. By gathering one of the largest collections of P. knowlesi whole-genome sequencing data, we studied structural genomic changes across sub-populations, with the analysis revealing differences in Borneo clusters linked to mosquito-related stages of the parasite cycle, in contrast to differences in host-related stages for the Peninsular group. Our work identifies new genetic exchange events, including introgressions between Malaysian Peninsular and M. nemestrina-associated clusters on various chromosomes, including in parasite invasion genes (DBPβ, NBPXα and NBPXβ), and important proteins expressed in the vertebrate parasite stages. Recombination events appear to have occurred between the Peninsular and M. fascicularis-associated groups, including in the DBPβ and DBPγ invasion associated genes. Overall, our work finds that genetic exchange events have occurred among the recognised contemporary groups of P. knowlesi parasites during their evolutionary history, leading to apparent mosaicism between these sub-populations. These findings generate new hypotheses relevant to parasite evolutionary biology and P. knowlesi epidemiology, which can inform malaria control approaches to containing the impact of zoonotic malaria on human communities.Publisher PDFPeer reviewe

    Population genetic analysis of Plasmodium knowlesi reveals differential selection and exchange events between Borneo and Peninsular sub-populations.

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    The zoonotic Plasmodium knowlesi parasite is a growing public health concern in Southeast Asia, especially in Malaysia, where elimination of P. falciparum and P. vivax malaria has been the focus of control efforts. Understanding of the genetic diversity of P. knowlesi parasites can provide insights into its evolution, population structure, diagnostics, transmission dynamics, and the emergence of drug resistance. Previous work has revealed that P. knowlesi fall into three main sub-populations distinguished by a combination of geographical location and macaque host (Macaca fascicularis and M. nemestrina). It has been shown that Malaysian Borneo groups display profound heterogeneity with long regions of high or low divergence resulting in mosaic patterns between sub-populations, with some evidence of chromosomal-segment exchanges. However, the genetic structure of non-Borneo sub-populations is less clear. By gathering one of the largest collections of P. knowlesi whole-genome sequencing data, we studied structural genomic changes across sub-populations, with the analysis revealing differences in Borneo clusters linked to mosquito-related stages of the parasite cycle, in contrast to differences in host-related stages for the Peninsular group. Our work identifies new genetic exchange events, including introgressions between Malaysian Peninsular and M. nemestrina-associated clusters on various chromosomes, including in parasite invasion genes (DBP[Formula: see text], NBPX[Formula: see text] and NBPX[Formula: see text]), and important proteins expressed in the vertebrate parasite stages. Recombination events appear to have occurred between the Peninsular and M. fascicularis-associated groups, including in the DBP[Formula: see text] and DBP[Formula: see text] invasion associated genes. Overall, our work finds that genetic exchange events have occurred among the recognised contemporary groups of P. knowlesi parasites during their evolutionary history, leading to apparent mosaicism between these sub-populations. These findings generate new hypotheses relevant to parasite evolutionary biology and P. knowlesi epidemiology, which can inform malaria control approaches to containing the impact of zoonotic malaria on human communities

    Biomonitoring Studies and Preventing the Formation of Biogenic H2S in the Wierzchowice Underground Gas Storage Facility

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    The article discusses the results of biomonitoring research at the Underground Gas Storage (UGS). Hydrogen sulphide, as one of the products of microbiological reaction and transformation, as well as a product of chemical reactions in rocks, is a subject of interest for global petroleum companies. The materials used in this research work were formation waters and stored natural gas. The biomonitoring of reservoir waters and cyclical analyses of the composition of gas stored at UGS Wierzchowice enabled the assessment of the microbiological condition of the reservoir environment and individual storage wells in subsequent years of operation. Investigations of the formation water from individual wells of the UGS Wierzchowice showed the presence of sulphate reducing bacteria bacteria (SRB), such as Desulfovibrio and Desulfotomaculum genera and bacteria that oxidize sulphur compounds. In the last cycles of UGS Wierzchowice, the content of hydrogen sulphide and sulphides in the reservoir waters ranged from 1.22 to 15.5 mg/dm3. The monitoring of natural gas received from UGS production wells and observation wells, which was carried out in terms of the determination of hydrogen sulphide and organic sulphur compounds, made it possible to observe changes in their content in natural gas in individual storage cycles. In the last cycles of UGS Wierzchowice, the content of hydrogen sulphide in natural gas from production wells ranged from 0.69 to 2.89 mg/dm3, and the content of organic sulphur compounds converted to elemental sulphur ranged from 0.055 to 0.130 mg Sel./Nm3. A higher hydrogen sulphide content was recorded in natural gas from observation wells in the range of 2.02–25.15 mg/Nm3. In order to explain the causes of hydrogen sulphide formation at UGS Wierzchowice, isotopic analyses were performed to determine the isotope composition of δ34SH2S, δ34SSO4, δ18OSO4 in natural gas samples (production and observation wells) and in the deep sample of reservoir water. The results of isotope tests in connection with microbiological tests, chromatographic analyses of sulphur compounds in natural gas collected from UGS Wierzchowice and an analysis of the geological structure of the Wierzchowice deposit allow us to conclude that the dominant processes responsible for the formation of hydrogen sulphide at UGS Wierzchowice are microbiological, consisting of microbial sulphate reduction (MSR). The presented tests allow for the control and maintenance of hydrogen sulphide at a low level in the natural gas received from the Wierzchowice Underground Gas Storage facility

    Niektóre problemy degradacji wodno-dyspersyjnych polimerowych płuczek wiertniczych rozprawa doktorska /

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    Tyt. z ekranu tytułowego.Praca doktorska. Akademia Górniczo-Hutnicza im. Stanisława Staszica (Kraków), 2006.Bibliogr.Dostępna także w wersji drukowanej.Tryb dostępu: Internet.Procesy degradacji płuczek wiertniczych, ich znaczenie w technologii wiercenia, technologia płuczek wiertniczych z uwzględnieniem roli procesów mikrobiologicznych, degradacja wodno-dyspersyjnych polimerowych płuczek wiertniczych pod wpływem działania mikroorganizmów, metodyka badań, badania laboratoryjne, omówienie wyników badań płuczek wiertniczych, wód bazowych, badań dotyczących wpływu pH środowiska na rozwój mikroorganizmów wyizolowanych z badanych płynów, procesów biodegradacji polimerów, zmian właściwości reologicznych roztworów związków polimerowych pod wpływem działania bakterii aerobowych, anaerobowych, efektywności działania biocydów w odniesieniu do płuczki wiertniczej, wody bazowej, efektywności działania biocydu ANTIMICROBIAL 7287 w odniesieniu do płuczki wiertniczej, BARDAC LF, BIOSTAT, DODIGEN 180-2, MODICIDE 340, w oparciu o zmiany właściwości reologicznych, przepuszczalności skał zbiornikowych pod wpływem działania bakterii wyizolowanych z płuczek wiertniczyc

    Biocide testing for the application in the oil and gas industry

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    Tyt. z nagłówka.Bibliogr. s. 252-[253].The paper discusses tests for effectiveness of three antibacterial substances for application in the national oil and gas industry. The substances were tested with reference to active cultures of microorganisms. These cultures were isolated, inter alia, from drilling fluids, produced waters and extraction sludge, and then multiplied and used in tests discussed in this publication. The tests demonstrated differences in particular tested substances in respect of effectiveness of their impact on aerobic and anaerobic bacteria and fungi. The results of the work will be used in industrial treatments in order to eliminate biogenic contamination, counteract biodegradation of drilling muds, and also for disinfection of reservoirs designed for storing water and other technological fluids.Dostępny również w formie drukowanej.KEYWORDS: biocide, microorganisms, triazine, peroxide, drilling fluid, biocidal activity

    Religious freedom of Minors in polish law and canon law of the Catholic Church

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    Praca magisterska pod tytułem ,,Wolność religijna osób małoletnich w prawie polskim i kanonicznym Kościoła katolickiego" prezentuje wolność religijną osób małoletnich w dwóch odrębnych porządkach prawnych- prawie polskim i kanonicznym Kościoła katolickiego. Jej celem jest rozważenie różnorodności rozumienia i definiowania pojęć ,,wolność religijna", ,,osoba małoletnia" oraz omówienie uprawnień i obowiązków składających się na wolność religijną osoby małoletniej w obu wyżej wymienionych porządkach prawnych. Składa się z trzech rozdziałów. Pierwszy rozdział jest poświęcony analizie pojęć ,,wolność religijna" i ,,osoba małoletnia", prezentuje brzmienie tych definicji w różnorodnych aktach prawnych i skutki takiego stanu rzeczy. Drugi rozdział prezentuje kolejny obszar badań i koncentruje się na wiązce uprawnień i obowiązków małoletniego wynikającej z prawa polskiego, omawia ich ewolucję w polskim konstytucjonaliźmie, prezentuje przepisy Konstytucji RP dotyczące wolności religijnej małoletniego, ratyfikowanych umów międzynarodowych i partykularnych ustaw odnoszących się do tejże tematyki. Omawia również działalność wyspecjalizowanych instytucji zajmujących się wolnością religjną małoletniego. Trzeci rozdział prrezentuje tematykę tytułowej wolności w prawie kanonicznym, omawia nie tylko uprawnienia i obowiązki małoletniego wynikające z analizy aktów prawnych dotyczących całego Kościoła, lecz te wynikające z aktów prawa Kościoła katolcikiego w Polsce.Zakończenie pracy przedstawia podsumowanie rozważań zawartych we wszystkich trzech rozdziałach. Bibliografia przedstawia pełną listę źródeł, na których oparto badania. Zawiera nie tylko akty prawne, literaturę czy wyroki sądowe, ale również autorskie tabele i wykresy.The MA Thesis titled ,, Religious freedom of Minors in polish and canon law of the Catholic Church" presents religious freedom of Minors in two separate law systems- polish law and canon law of Catholic Church. Its' goal is to consider differences in understanding and defining of words ,,relgious freedom", ,,Minor" and to present rights and obligations that make up religious freedom of Minor in both of the aforementioned law systems. MA Thesis considers three chapters. First chapter is dedicated to analize the concept of ,,religious freedom" and ,,Minor". It presents legal definitions of this words in different legal acts and results of this differences. Second chapter presents another area of tests and concentrates on rights and obligations of Minor in polish law. It describes its' evolution in polish constitutional law, presents regulations of polish constitution related to relgious freedom of minor, ratified international acts and particular legal acts related to this topic. It also presents business of specialized institutions concentrated on relgious freedom of Minors. Third chapter presents the subject matter of relgious freedom in canon law, describes not only rights and obligations in canon law dedicated to whole Catholic Church, but also those contained in law made by polish Catholic Church. Summary presents all thoughts contained in all the chapters. Bibliography presents whole list of sources. It containes not only legal acts, literature or court judgments but also tables and charts made by author
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