523 research outputs found
THE PARTICULARITIES OF PRODUCT COST CALCULATION AT THE ENTERPRISES WITH SEASONAL ACTIVITY
This article comprehends the problems of cost calculation at theenterprises with seasonal activity. The practical recommendations are based onorganizational and technological features corresponding to peculiarities of theseasonal production. Here we can mention: the creation and the accounting ofprovisions for certain types of costs for raw materials, for reparation of assets;calculation of depreciation of productive assets by the method of production using therecalculation of planned volume to factual volume of production; the reciprocalmethod using the proceeding of proper factual unit cost of the service department etc.cost, calculation of cost, correlation coefficient, services of interdependentsections, distribution basis, and method of cost calculation.
Modeling, Verification and Testing of P Systems Using Rodin and ProB
In this paper we present an approach to modelling, verification and testing
for cell-like P-systems based on Event-B and the Rodin platform. We present a general
framework for modelling P systems using Event-B, which we then use to implement two
P-system models in the Rodin platform. For each of the two models, we use the associated
Pro-B model checker to verify properties and we present some of the results obtaine
Consumul de pește în rândul populației Republicii Moldova
Organizația pentru Agricultură și Alimentație a Națiunilor Unite, Agenția Națională pentru Sănătate Publică, Chișinău, Republica Moldova, Catedra de igienă generală, USMF „Nicolae Testemiţanu”, Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova, Ziua internațională a științei pentru pace și dezvoltareBackground. At present, very little is known about the consumption of different fish species at national
level. The elucidation of this topic would be useful both for assessing the risk of exposure of the
population to various chemical contaminants and for assessing the associated benefits. Objective of the
study. The purpose of this study was to identify which fish species are consumed by the population of
the Republic of Moldova. Material and Methods. FishStatJ v4.00.9 software was used to estimate fish
species consumed nationally. The data extracted, per species, (annual series) for the period 2005-2017,
in tons per year were converted into grams per day per capita. To exclude the inedible component
conversion factors were applied. Results. The application of conversion factors decreased the average
consumption by 34.7%. In the period 2005-2017 there was an increasing trend (y=0.4016x+16.88;
R²=0.4036x) from 17.8g/day (2005) to 23.6g/day (2017), on average per capita was consumed
19.68g/day. 97.3% of the average consumption are: herring/sardines - 6.46g/day (32.8%), carp -
4.14g/day (21.0%), unspecified species - 3.09g/day (15.7%), mackerel - 1.61g/day (8.17% ), hake -
1.10g/day (5.6%), blue whiting - 0.953g/day (4.84%), salmon - 0.824g/day (4.19%), cod - 0.745g/day
(3.78%), polak - 0.22g/day (1.14%), tuna - 0.09g/day (0.47%). During the analyzed period, 26 species
of fish were consumed. Conclusion. The population consumes 26 different species of fish.
Herring/sardines and carp are the most consumed species with a share of 32.8% and 21.0% respectively.
Another 15.7% of average consumption remains uncertain because the species could not be identified.
Introducere. La momentul actual, se cunoaște foarte puțin despre consumul diferitor specii de pești la
nivel național. Elucidarea acestui subiect ar fi utilă atât pentru evaluarea riscului expunerii populației la
diferiți contaminanți chimici, cât și pentru aprecierea beneficiilor asociate. Scopul lucrării. Scopul
acestui studiu a fost de a identifica care sunt speciile de pești consumate de către populația din Republica
Moldova. Material și Metode. Pentru estimarea speciilor de pești consumate la nivel național s-a
utilizat softul FishStatJ v4.00.9. Datele extrase per specie (serii anuale) pentru perioada 2005-2017, în
tone pe an s-au transformat în grame pe zi per capita. Pentru a exclude componenta necomestibilă s-au
aplicat factori de conversie. Rezultate. Aplicarea factorilor de conversie a micșorat consumul în mediu
cu 34.7%. În perioada 2005-2017 s-a înregistrat o tendință de creștere (y=0.4016x+16.88; R²=0.4036x)
de la 17.8g/zi (2005) la 23.6g/zi (2017), în mediu per capita s-a consumat 19.68g/zi. 97.3% din consumul
mediu constituie: hering/sardine - 6.46g/zi (32.8%), crap - 4.14g/zi (21.0%), specii nespecificate –
3.09g/zi (15.7%), macrou – 1.61g/zi (8.17%), merluciu – 1.10g/zi (5.6%), putasu – 0.953g/zi (4.84%),
somon – 0.824g/zi (4.19%), batog – 0.745g/zi (3.78%), polac - 0.22g/zi (1.14%), ton – 0.09g/zi (0.47%).
În perioada analizată s-au consumat 26 specii de pești. Concluzii. Populația consumă 26 specii diferite
de pești. Hering/ sardinele și crapul sunt cele mai consumate specii cu o pondere de 32.8% și 21.0%,
respectiv. Alte 15.7% din consumul mediu rămân a fi incerte deoarece nu s-a putut identifica speciile
Valorisation des granulats recyclés dans les bétons soumis au gel/dégel sans saturation (classes d’exposition F et R)
Cette étude consiste à analyser les propriétés du béton destiné aux applications résidentielles dans lesquelles une partie des granulats naturels (GN) sont remplacés par des granulats recyclés (GR). On analyse les impacts sur la résistance, la durabilité et la microstructure du béton en fonction du taux de remplacement. Trois différents types des GR sont étudiés. Les essais de caractérisation des granulats recyclés, tels que la densité, l’absorption, la granulométrie, la teneur en impuretés, en matières organiques et en ions chlorure sont effectués. Les essais réalisés sur les bétons se résument essentiellement aux essais de la résistance à la compression, du retrait de séchage, de la résistance aux cycles de gels-dégels, de la perméabilité aux ions chlorure et de la résistivité électrique. Dans le but d’identifier l’effet des granulats fins recyclés sur le comportement des bétons, les analyses thermogravimétriques (ATG) et le pH des mortiers à base des granulats recyclés sont également déterminés.
Les bétons évalués dans le cadre de cette étude de classes d’exposition « F-2 » et « R » sont destinés pour la construction résidentielle et des petits bâtiments. Compte tenu de critère de résistance plus sévère, le béton choisi pour les essais est de classe F-2 selon la classification de la norme CSA A23.1-14 (annexe 1 et 40). La norme prévoit que le béton soit soumis aux cycles de gels-dégels dans des conditions non saturées, mais ne soit pas exposé aux ions chlorure. À titre d’exemples, on peut nommer les murs et les poteaux extérieurs. La norme CSA établit les propriétés minimales pour un béton de classe F-2 (annexe 2). Ainsi, la formulation vise un rapport eau/liant (E/L) de 0.55 et une teneur en air de 4 à 6% selon le diamètre maximal du gros granulat utilisé (annexe 3).
Les formules des bétons sont déterminées par la méthode des volumes absolus (CAN-A23.1-94 et ACI 211.1-74). Dans cette étude, le liant utilisé est le ciment de type GU, le ciment binaire à base de laitier et les ciments ternaires à base de laitier et fumée de silice ou à base de cendres volantes et fumée de silice.
Les GR sont composés de gros granulats et de granulats fins. Le remplacement du GN par le granulat recyclé est effectué de la manière suivante : une proportion des granulats fins recyclés remplace le sable et une partie des gros granulats recyclés remplace les gros granulats naturels. Les proportions massiques des granulats naturels dans le mélange sont effectuées suite à une optimisation granulaire des matériaux par rapport à la courbe visée de Fuller et Thompson (Gagné et Aïtcin, 2014).
Bien que certaines propriétés des bétons aux GR et ciment GU soient plus faibles, comparativement aux propriétées des bétons aux granulats naturels, il est possible d’obtenir la résistance à la compression minimale de 25 MPa à 28 jours, recommandée par la norme CSA A23.1-14 (bétons de classe F2), en optimisant le taux de remplacement des granulats recyclés de 15% pour un béton formulé avec du ciment GU et de 45% pour un béton formulé avec du ciment binaire au laitier.
Mots-clés : Béton résidentiel, ciment binaire, ciment de type GU, ciment ternaire, durabilité, granulats recyclés, méthode des volumes absolus, optimisation des granulats, résistance
The psyhofarmacologic management of suicidal risk in patients with schizophrenia
Emergency Department, Hospital of Psychiatry, Chisinau, the Republic of MoldovaBackground: Managing the risk of suicide of patients with schizophrenia presents numerous challenges for clinicians. Compared with the general population,
these patients have a risk of 8.5 percent more then others to commit a suicide. The literature that discusses the risk management of suicidal patients with
schizophrenia is unanimous in the view that the problem statement requires only an integrated approach through psychosocial and pharmacological
measures. The priority belongs to the antipsychotic drugs that can protect against suicidal risk. The second important target of medicine is removing
the depressive symptoms in patients with schizophrenia. It is necessary to find out new methods, more effective treatments for suicidal behaviour and
ideas of patients with schizophrenia.
Conclusions: The treatment of patients with schizophrenia, that are at risk of suicide, involves a careful assessment of the risk factors and the development
of a broad security plan that includes pharmaceutical and psycho-social interventions, which, if persevered for a long time, can minimize the risk of
suicide. Carefully and judiciously selected antipsychotic medication may protect against suicidal risk, in this case, first-generation antipsychotics can be
effective if regularly administered in adequate doses and invariably combined with antidepressants. Material accumulated evidence argues in favor of
the second generation antipsychotics such as clozapine, which, according to some approved estimations, managed to decrease the suicide rate by 88%.
Treatment of depressive symptoms in patients with schizophrenia is a task of first value, being well-known that the presence and especially the severity
of the depressive status in these patients present a major risk for suicide. Selective receptor inhibitors (SSRI) and serotonin receptors are operators in
relieving symptoms in patients with depressive schizophrenia as they can decrease the suicidal ideas
Evaluation of nonsteroidal anti-inflammatory drugs use in the elderly
Department of Social Pharmacy Vasile
Procopisin,
Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of MoldovaIntroduction. According to National Bureau of statistics of the Republic of Moldova, 15,7% of
chronic diseases in the geriatric population represent conditions of osteoarticular system.
NSAIDs play a major role in the management of acute and chronic pain syndromes, they
effectively relieve pain, but also these drugs are known to produce serious side-effects and can
potentiate, increase or decrease the effect of many prescription and non-prescription drugs that
elderly population takes. Tools and tips to monitor NSAIDs use provided by pharmacists can
enhance understanding the benefits and the potential risks of pain relief medicines, help elderly
patients be able to indentify typical side-effects and cautions, avoid complications and be aware
of use them correctly.
Aim of the study. The purpose of this study is to underscore how pharmacists appreciate
NSAID drugs use in the elderly and to present tips for pharmacists that will help elderly patients
to be aware of potential risks of NSAIDs inappropriate use.
Materials and methods. It is a longitudinal study in which all the variables were collected from
December to March 2018. A standardized questionnaire, with 8 closed-ended and 2 open-ended
questions, was applied. Participants, drugs consumers, were visitors of community pharmacy. A
descriptive analysis was performed; descriptive statistics such as mean, frequencies and
percentages were used to describe and summarize the data. All analyses were performed using
SPSS for Windows version 22.0.
Results. Data suggest that current patient perception on NSAIDs is poor. In pharmacist’s point
of view, elderly patients practice self-medication with NSAIDs (71%) and only 11% of
pharmacists reported that the knowledge of elderly about NSAIDs are sufficient; additionally, in
75% of cases elderly didn’t reporte side effects caused by NSAIDs. The NSAIDs drugs
requested by elderly are diclofenac and ibuprofen (80 responses), followed by paracetamol (34),
nimesulid (29), desketoprofen (26), aspirin (22) and less than 20 responses – indomethacin,
meloxicam, naproxen, metamizol and ketorolac. 66% of elderly patient return in particular
pharmacy for counseling and select the NSAID drug according to pharmacist’s recommendation
(82,7%). The majority of pharmacists listed such abilities as empathy, patience, amiability,
simple language, and professionalism necessary to enhance communication with elderly.
Conclusions. Before taking NSAIDs medication, elderly patients should be aware of the risks
involved through detailed discussion with healthcare providers, including pharmacists. The
community pharmacist can play an essential role in ensuring safe use of NSAID through
regularly review pain relief medicines taken by older people, such as diclofenac, ibuprofen and
paracetamol etc
Particularities of accounting for construction contracts
SUSTAINABLE ECONOMIC DEVELOPMENT: INTERNATIONAL AND NATIONAL ASPECTS (Novopolotsk, 25 - 26 October 2012) V.1 Turcanu L.Секция 1. АКТУАЛЬНЫЕ ПРОБЛЕМЫ УЧЕТА, АНАЛИЗА И КОНТРОЛЯ В КОНТЕКСТЕ УСТОЙЧИВОГО РАЗВИТИЯ: МЕЖДУНАРОДНЫЕ И НАЦИОНАЛЬНЫЕ АСПЕКТ
Risk behavior of pupils from rural areas in correlation with living in the house adults
State University of Medicine and Pharmacy
Nicolae Testemitanu
National Center of Public Health, Chisinau, Republic of Moldova
The 6th International Medical Congress for Students and Young DoctorsYoung generation’s behavior can be influenced by adults who live in the same
house
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