1,332 research outputs found

    Experiments to Establish Current-carrying Capacity of Thermionic-emitting Cathodes Final Report, 11 Jan. 1966 - 30 Jan. 1967

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    Current carrying capabilities of thermionic cathodes in nitrogen at pressure levels above one atmospher

    Substratum-Associated Microbiota

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    Ethical challenges in researching and telling the stories of recently deceased people

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    This paper explores ethical challenges encountered when conducting research about, and telling, the stories of individuals who had died before the research began. Cases were explored where individuals who lived alone had died alone at home and where their bodies had been undiscovered for an extended period. The ethical review process had not had anything significant to say about the deceased ‘participants’. As social researchers we considered whether it was ethical to involve deceased people in research when they had no opportunity to decline, and we were concerned about how to report such research. The idea that the dead can be harmed did not help our decision-making processes, but the notion of the dead having limited human rights conferred upon them was useful and aided us in clarifying how to conduct our research and disseminate our findings.Peer reviewe

    Lenalidomide before and after Autologous Hematopoietic Stem Cell Transplantation in Multiple Myeloma

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    Although multiple myeloma remains incurable outside of allogeneic hematopoietic stem cell transplantation, novel agents made available only in the last few decades have nonetheless tremendously improved the landscape of myeloma treatment. Lenalidomide, of the immunomodulatory class of drugs, is one of those novel agents. In the non-transplant and relapsed/refractory settings, lenalidomide clearly benefits patients in terms of virtually all meaningful outcomes including overall survival. Data supporting the usage of lenalidomide as part of treatment approaches incorporating high-dose chemotherapy with autologous stem cell support (ASCT) are less mature as pertains to such long-term outcomes and toxicity, and lenalidomide is not currently approved by regulatory agencies for use in the context of ASCT in either the United States or Europe. That said, relatively preliminary efficacy data describing lenalidomide as a component of ASCT-based treatment approaches to MM are indeed promising, and consequently lenalidomide's role in ASCT-based treatment strategies is growing. In this review we summarize existing data that pertains to lenalidomide in the specific context of ASCT, and we share our thoughts on how our own group applies these data to approach this complex issue clinically

    Physical activity in US Blacks: a systematic review and critical examination of self-report instruments

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    <p>Abstract</p> <p>Background</p> <p>Physical activity self-report instruments in the US have largely been developed for and validated in White samples. Despite calls to validate existing instruments in more diverse samples, relatively few instruments have been validated in US Blacks. Emerging evidence suggests that these instruments may have differential validity in Black populations.</p> <p>Purpose</p> <p>This report reviews and evaluates the validity and reliability of self-reported measures of physical activity in Blacks and makes recommendations for future directions.</p> <p>Methods</p> <p>A systematic literature review was conducted to identify published reports with construct or criterion validity evaluated in samples that included Blacks. Studies that reported results separately for Blacks were examined.</p> <p>Results</p> <p>The review identified 10 instruments validated in nine manuscripts. Criterion validity correlations tended to be low to moderate. No study has compared the validity of multiple instruments in a single sample of Blacks.</p> <p>Conclusion</p> <p>There is a need for efforts validating self-report physical activity instruments in Blacks, particularly those evaluating the relative validity of instruments in a single sample.</p

    Up and Out: Journalism, Social Media, and Historical Sensibility

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    Much of the modern theorizing about journalism and communication attained its robustness due to a powerful convergence of distinct middle-range scholarly findings that emerged primarily in the 1970s and 1980s. In the present day, when we turn our analytical gaze to the relationship between journalism and social media, we thus need to strike a delicate balance between conducting new qualitative research, re-conceptualizing and re-interrogating the classic conclusions of political communication scholarship, and linking these two aspects of research together. However, we might also wish to extend our analytical gaze “out,” interrogating the movement of journalistic technology across history, as well as “up,” looking at how journalism fits within larger structural explanations regarding the shape of political life

    Transitionless quantum drivings for the harmonic oscillator

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    Two methods to change a quantum harmonic oscillator frequency without transitions in a finite time are described and compared. The first method, a transitionless-tracking algorithm, makes use of a generalized harmonic oscillator and a non-local potential. The second method, based on engineering an invariant of motion, only modifies the harmonic frequency in time, keeping the potential local at all times.Comment: 11 pages, 1 figure. Submitted for publicatio

    Twitter and non-elites. Interpreting power dynamics in the life story of the (#)BRCA Twitter stream

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    In May 2013 and March 2015, actress Angelina Jolie wrote in the New York Times about her choice to undergo preventive surgery. In her two op-eds she explained that - as a carrier of the BRCA1 gene mutation - preventive surgery was the best way to lower her heightened risk of developing breast and ovarian cancer. By applying a digital methods approach to BRCA-related tweets from 2013 and 2015, before, during and after the exposure of Jolie’s story, this study maps and interprets Twitter discursive dynamics at two time points of the BRCA Twitter stream. Findings show an evolution in curation and framing dynamics occurring between 2013 and 2015, with individual patient advocates replacing advocacy organisations as top curators of BRCA content and coming to prominence as providers of specialist illness narratives. These results suggest that between 2013 and 2015, Twitter went from functioning primarily as an organisation-centred news reporting mechanism, to working as a crowdsourced specialist awareness system. This paper advances a twofold contribution. First, it points at Twitter’s fluid functionality for an issue public and suggests that by looking at the life story – rather than at a single time point – of an issue-based Twitter stream we can track the evolution of power roles underlying discursive practices and better interpret the emergence of non-elite actors in the public arena. Second, the study provides evidence of the rise of activist cultures that rely on fluid, non-elite, collective and individual social media engagement

    Localization and Anomalous Transport in a 1-D Soft Boson Optical Lattice

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    We study the dynamics of Bose-Einstein condensed atoms in a 1-D optical lattice potential in a regime where the collective (Josephson) tunneling energy is comparable with the on-site interaction energy, and the number of particles per lattice site is mesoscopically large. By directly imaging the motion of atoms in the lattice, we observe an abrupt suppression of atom transport through the array for a critical ratio of these energies, consistent with quantum fluctuation induced localization. Directly below the onset of localization, the frequency of the observed superfluid transport can be explained by a phonon excitation but deviates substantially from that predicted by the hydrodynamic/Gross-Pitaevskii equations.Comment: 14 pages, 5 figure

    ‘I’d be proud to spend the sacred foreign aid budget on our poor pensioners’: Representations of macro aid resourcing in the Irish, UK and US print-media during the economic crisis, 2008–2011

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    The news-media has been identified as an influence on donor nations’ overseas aid allocations, acting as a site where decisions are justified to ‘domestic constituencies’ and through which resistance is mobilised. Mediated pressures on aid allocations amplified between 2008 and 2011 in three donor countries experiencing domestic economic difficulties: Ireland, the UK and the US. This study suggests that each country’s print-media positioned the macro resourcing of aid primarily as an inward concern, neglected recipient country needs, and made weak connections to international policy frameworks to benchmark, contextualise and rationalise aid allocations. The research suggests that the explanatory limitations of the countries’ news-models in communicating the processes and rationales underpinning macro aid resourcing may be a factor in sustaining a knowledge and legitimacy deficit among domestic publics for international aid agreements
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