Assessment of the requisites of microbiology based infectious disease training under the pressure of consultation needs

<p>Abstract</p> <p>Background</p> <p>Training of infectious disease (ID) specialists is structured on classical clinical microbiology training in Turkey and ID specialists work as clinical microbiologists at the same time. Hence, this study aimed to determine the clinical skills and knowledge required by clinical microbiologists.</p> <p>Methods</p> <p>A cross-sectional study was carried out between June 1, 2010 and September 15, 2010 in 32 ID departments in Turkey. Only patients hospitalized and followed up in the ID departments between January-June 2010 who required consultation with other disciplines were included.</p> <p>Results</p> <p>A total of 605 patients undergoing 1343 consultations were included, with pulmonology, neurology, cardiology, gastroenterology, nephrology, dermatology, haematology, and endocrinology being the most frequent consultation specialties. The consultation patterns were quite similar and were not affected by either the nature of infections or the critical clinical status of ID patients.</p> <p>Conclusions</p> <p>The results of our study show that certain internal medicine subdisciplines such as pulmonology, neurology and dermatology appear to be the principal clinical requisites in the training of ID specialists, rather than internal medicine as a whole.</p

Pediatric tracheotomy: Results of a single center study on 46 patients

In this study, we aimed to present our tracheotomy experiences in pediatric patients in our hospital. We reviewed the data by analyzing pediatric tracheotomy retrospectively in terms of indications, follow-up and complications. Forty-six pediatric patients who underwent tracheotomy between 2014 and 2021 were included. The indications were examined under five headings according to the diagnoses that led to the tracheotomy of the patients. These were prolonged intubation, upper airway obstruction, craniofacial anomalies, neuromuscular disorders, and postoperative-traumatic sequelae. Twenty-three (50%) of these patients were girls, and 23 (50%) were boys. The mean age of the patients was 53.8±62.9 months. The youngest patient was a 1-day-old newborn, while the oldest patient was 15 years old. Pediatric tracheotomy was performed in 14 patients for prolonged intubation, 12 patients for craniofacial anomalies, 7 patients for upper airway obstruction, 7 patients for postoperative-traumatic sequelae and 6 patients for neuromuscular disorders. Preoperative or postoperative complications were seen in 10 of the patients. The intubation time of the patients who underwent elective tracheotomy was calculated as 25.7±17.1 days. Of these patients, the shortest duration of intubation was 6 days, and the longest duration was 90 days. The smallest diameter of the tracheostomy cannula inserted in the patients was 2.5 mm, while the largest was 7 mm, and the mean was 4.5 mm. In the follow-ups, it was observed that only 6 of the patients were decannulated, 11 of them died, and the remaining 29 continued their lives with tracheostomy. As a result, although pediatric tracheotomy is rare, it is a life-saving surgical procedure for the appropriate indications and can be successfully performed with manageable complications, contrary to expectations, with the appropriate surgical technique and adequate postoperative care. [Med-Science 2022; 11(1.000): 382-6

Inflammatory Myofibroblastic Tumor: A Rare Tumor in the Tongue

Inflammatory myofibroblastic tumor is composed of myofibroblast and inflammatory cell infiltration of the tissue. Malign transformation and recurrence rate of this tumor is rare and accepted as benign fibroinflammatory disease. The main etiology is unclear, but infection, trauma, and immunologic event are accused. In this study, we presented a 75-year-old man with a mass on his tongue, which was diagnosed as “inflammatory myofibroblastic tumor.” This type of tumor is rarely seen in the tongue and might be difficult to diagnose. Complete mass excision was provided for an adaquete treatment

The relationship between childhood trauma and the course of disease in female patients with bipolar disorder

Purpose This study aimed to determine the history of childhood trauma and the relationship between childhood trauma and the course of the disease in female patients with bipolar disorder

Assessment of mucosal changes associated with nasal splint in a rabbit model

INTRODUCTION: There is no consensus on duration of the nasal splint after nasal septum surgeries. The pressure of nasal splint on the mucosa may cause tissue necrosis and nasal septum perforation.OBJECTIVES: To investigate the histopathological changes of the nasal mucosa caused by nasal splints in a rabbit model.METHODS: No splint was used in group A. Bilateral silicone nasal splints were placed for five, ten, and 15 days in groups B, C, and D, respectively. Biopsy of the nasal mucosa was performed after removal of splint. Histopathologic evaluations were performed. The severity and depth of the inflammation were scored.RESULTS: Group A had a normal histological appearance. Comparison of the results of groups B, C, and D with group A demonstrated statistically significant differences with regards to the severity of histopathological findings. There was no statistically significant difference between groups B and C. There were statistically significant differences between the groups B and D, and also between groups C and D.CONCLUSIONS: Longer duration of nasal splint had a higher risk for septal perforation. Therefore, removal of the splint as soon as possible may be helpful for preventing potential perforations

Prevalence of the Helicobacter pylori in the tonsils and adenoids

INTRODUCTION: There is an ongoing debate about the existence and effects of Helicobacter pylori (Hp) in adenotonsillar tissue. OBJECTIVE: A clinical study was conducted to assess the existence of Hp in the adenoid and/or adenotonsillar tissues, which were surgically excised due to chronic adenotonsillitis. METHODS: Phosphoglucosamine mutase gene for the detection of Hp and cytotoxin-associated gene as virulence gene were examined in 84 adenotonsillar tissues obtained from 64 patients and patients' serum by using polymerase chain reaction. RESULTS: Hp IgG was detected in 57 (89%) patients' serum. A total of seven tissue samples from 64 patients (10.9%) were found positive for Hp DNA, of which five were adenoids and two were tonsil tissues. All polymerase chain reaction positive samples were also positive for the cytotoxin-associated gene, which is a virulence determinant for the organism. CONCLUSION: This study suggests that children are exposed to Hp at an early age of their life in this province. Hp may have a role in the pathogenesis of chronic adenotonsillitis, especially in endemic areas

Occult hepatitis B infection in Turkish HIV-infected patients: A multicentre, retrospective, cross-sectional study, Schindler study

Objective Occult hepatitis B infection (OHBI) appears to have a higher prevalence in populations at high risk for hepatitis B virus (HBV) infection with concomitant liver disease. The aim was to assess the prevalence of OHBI in a sample of human immunodeficiency virus -1 positive and HBV surface antigen-negative (HIV-1+/HBsAg-) Turkish patients

Real-life Data for Tenofovir Alafenamide Fumarate Treatment of Hepatitis B: the Pythagoras Cohort

Background: Chronic hepatitis B (CHB) is a viral infection that can result in life-threatening conditions, such as hepatocellular carcinoma and cirrhosis. Tenofovir, which is used for the treatment of CHB, is a nucleotide analog that inhibits HBV-DNApolymerase and has two formulations: disoproxil and alafenamide. In contrast to tenofovir disoproxil fumarate (TDF), tenofovir alafenamide fumarate (TAF) penetrates the whole hepatocyte without being eliminated due to its longer plasma half-life and greater plasma stability. As a result, side effects such as proximal renal tubulopathy and loss of bone density are less common in the treatment of TAF and have similar efficacy to TDF