Educar los conceptos del factor de retención de una empresa con el caso del aumento del nivel de compromiso de los empleados

The current socio-economic situation creates similar conditions and rules for companies in various industries around the world.in this vein, the study and educate the retention factors of the company are of a great importance.  The task of staff productivity increase and the overall effectiveness of its activities is relevant. The most important role in addressing the issue of employee productivity and performance increasing, as well as his retention is played by employee engagement. The researchers studying engagement at work recognize that this phenomenon is multifaceted and define it as an employee's physical, cognitive and emotional state, causing excessive performance of his functional duties. Involvement is interconnected with the motivational potential of work, therefore, the conditions for the engagement development are the following ones: work significance and diversity, the comparison of work with its result. The authors of the article conducted the study of engagement at work in the enterprises of fishing and fish processing industries. We determined the problems that impede the growth of staff engagement. The authors of the article implemented the program of corrective actions aimed to improve the factors affecting the engagement at work and retention of staff. We determined the interdependence of involvement level and the coefficient of staff turnover, as well as the return of employees to some holding.La situación socioeconómica actual crea condiciones y reglas similares para las empresas de diversas industrias en todo el mundo. En este sentido, el estudio y la educación de los factores de retención de la empresa son de gran importancia. La tarea de aumentar la productividad del personal y la efectividad general de sus actividades es relevante. El papel más importante para abordar el problema del aumento de la productividad y el rendimiento de los empleados, así como su retención, lo desempeña el compromiso de los empleados. Los investigadores que estudian el compromiso en el trabajo reconocen que este fenómeno es multifacético y lo definen como el estado físico, cognitivo y emocional de un empleado, lo que provoca un desempeño excesivo de sus deberes funcionales. La participación está interconectada con el potencial motivador del trabajo, por lo tanto, las condiciones para el desarrollo del compromiso son las siguientes: importancia y diversidad del trabajo, la comparación del trabajo con su resultado. Los autores del artículo realizaron el estudio de la participación en el trabajo en las empresas de lasindustrias pesqueras y de procesamiento de pescado. Determinamos los problemas que impiden el crecimiento de la participación del personal. Los autores del artículo implementaron el programa de acciones correctivas destinadas a mejorar los factores que afectan el compromiso en el trabajo y la retención del personal. Determinamos la interdependencia del nivel de participación y el coeficiente de rotación del personal, así como el retorno de los empleados a alguna explotación

Educating the Concepts of Retention Factor of a Company with the Case of Employee Engagement Level Increase

The current socio-economic situation creates similar conditions and rules for companies in various industries around the world.in this vein, the study and educate the retention factors of the company are of a great importance.  The task of staff productivity increase and the overall effectiveness of its activities is relevant. The most important role in addressing the issue of employee productivity and performance increasing, as well as his retention is played by employee engagement. The researchers studying engagement at work recognize that this phenomenon is multifaceted and define it as an employee's physical, cognitive and emotional state, causing excessive performance of his functional duties. Involvement is interconnected with the motivational potential of work, therefore, the conditions for the engagement development are the following ones: work significance and diversity, the comparison of work with its result. The authors of the article conducted the study of engagement at work in the enterprises of fishing and fish processing industries. We determined the problems that impede the growth of staff engagement. The authors of the article implemented the program of corrective actions aimed to improve the factors affecting the engagement at work and retention of staff. We determined the interdependence of involvement level and the coefficient of staff turnover, as well as the return of employees to some holding

Self-realization of students in work of small innovative enterprises as factor of strengthening their psychological well-being and health

The circumstances and conditions for improving the psychological health of students through their participation in the activity of small innovative enterprises established on university base are considered. The authors reveal essence of students’ self-realization in work of these enterprises, and also the main trends of students’ psychological well-being, such as: a personal involvement into entrepreneurship activity, realization of internal capacities and potential, social cooperation into scientific and innovation project

Механизмы развития легочной гипертензии при COVID-19

The novel coronavirus infection caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome-relate CoronaVirus 2) is a serious disease often associated with cardiovascular complications. The combination of acute respiratory distress syndrome, invasive ventilation, thromboembolic complications, and direct myocardial injury creates conditions that increase likelihood of right ventricular (RV) dysfunction due to pulmonary hypertension (PH). The aim of the work was to search for literature sources in the PubMed, Google Scholar and eLibrary databases and analyze these sources to elucidate the main pathophysiological mechanisms that underly the onset and progression of PH in COVID-19 (COronaVIrus Disease 2019). Viral damage to the myocardium and pulmonary vascular endothelium in hospitalized patients with COVID-19 may contribute to the development of PH, which is associated with signs of a more severe course of the disease and the development of RV failure in the future. Results. It was concluded that the routine echocardiography protocol should be expanded with additional indicators of the right ventricular function, since these data can be used can be used to predict course of the disease. Conclusion. Based on the literature data, COVID-19 can lead to the development of clinically significant PH in some cases.Новая коронавирусная инфекция (НКИ), вызванная SARS-CoV-2 (Severe Acute Respiratory Syndrome-relate CoronaVirus 2), представляет собой серьезное заболевание, часто связанное с сердечно-сосудистыми осложнениями. Сочетание острого респираторного дистресс-синдрома, инвазивной вентиляции легких, тромбоэмболических осложнений, а также прямого повреждения миокарда создает условия, при которых вероятно развитие дисфункции правого желудочка (ПЖ) вследствие легочной гипертензии (ЛГ). Целью работы явился поиск литературных источников в базах данных PubMed, Google Scholar и eLibrary и последующий их анализ для выяснения основных патофизиологических механизмов, которые играют роль в возникновении и прогрессировании ЛГ при COVID-19 (COronaVIrus Disease 2019). Повреждение вирусом миокарда, а также эндотелия легочных сосудов у госпитализированных пациентов с COVID-19 может способствовать развитию ЛГ, связанной с признаками более тяжелого течения заболевания и развитием недостаточности ПЖ в дальнейшем. Результаты. Установлено, что рутинный протокол эхокардиографического исследования следует расширить дополнительными показателями, которые свидетельствовали бы о функции ПЖ, поскольку эти данные могут применяться в качестве прогностического фактора риска. Заключение. По результатам анализа данных литературы показано, что НКИ в ряде случаев может приводить к развитию клинически значимой ЛГ

Influence of single amino acid substitutions in the hemagglutinin on the antigenic and receptor-binding properties of influenza virus B/Florida/04/2006 of Yamagata-like evolutionary lineage

Influenza A and B viruses use sialylated oligosaccharide chains expressed on the surface of a host cell as the cell entry receptors. The type of the bond between sialic acid (SA) and the neighboring galactose residue (Gal) is one of the main characteristics that define the type of receptor. Influenza viruses recognize SAα2-3Gal- or SAα2-6Gal-structures on the surface of the cells. Influenza A viruses of avian origin bind α2-3-sialylated glycans, while the human strains bind preferentially α2-6-sialylated ones. However, the receptor-binding specificity of influenza B viruses has not been characterized sufficiently so far. In this study, we selected the escape mutants of influenza B/Florida/04/2006 strain (Yamagata-like lineage) using monoclonal antibodies (mAb) to hemagglutinin (HA). The analysis of the amino acid sequences of mAb-induced escape mutants revealed the single amino acid substitutions 40Tyr→His, 85His→Tyr, 202Asn→Lys and 242Ser→Arg in 10F4-, 8Н11-, 8Н3- and 9А3-induced HA variants, correspondingly. It was shown that the single amino acid substitutions 202Asn→Lys and 242Ser→Arg alter the receptor-binding specificity of the influenza B virus. These findings are important for the understanding of the influence of individual amino acid residues in HA on the receptor-binding properties of influenza B Yamagata-like lineage viruses and allow us to predict the possible ways of their evolution.Influenza A and B viruses use sialylated oligosaccharide chains expressed on the surface of a host cell as the cell entry receptors. The type of the bond between sialic acid (SA) and the neighboring galactose residue (Gal) is one of the main characteristics that define the type of receptor. Influenza viruses recognize SAα2-3Gal- or SAα2-6Gal-structures on the surface of the cells. Influenza A viruses of avian origin bind α2-3-sialylated glycans, while the human strains bind preferentially α2-6-sialylated ones. However, the receptor-binding specificity of influenza B viruses has not been characterized sufficiently so far. In this study, we selected the escape mutants of influenza B/Florida/04/2006 strain (Yamagata-like lineage) using monoclonal antibodies (mAb) to hemagglutinin (HA). The analysis of the amino acid sequences of mAb-induced escape mutants revealed the single amino acid substitutions 40Tyr→His, 85His→Tyr, 202Asn→Lys and 242Ser→Arg in 10F4-, 8Н11-, 8Н3- and 9А3-induced HA variants, correspondingly. It was shown that the single amino acid substitutions 202Asn→Lys and 242Ser→Arg alter the receptor-binding specificity of the influenza B virus. These findings are important for the understanding of the influence of individual amino acid residues in HA on the receptor-binding properties of influenza B Yamagata-like lineage viruses and allow us to predict the possible ways of their evolution

The activated charcoal adsorption of phenol

The problems of treatment of the waste water were considered in this work. The main method of the activated charcoal adsorption of phenol was investigated. The adsorption properties of the adsorbent were also considered. Along with it Langmuir's and Friendlich's adsorption isotherm has been studied and analyzed

Development of the cell-ELISA test for the subtype identification of circulating influenza A(H1) and A(H3) viruses

The sensitive version of cell-ELISA was developed for the subtype-specific differentiation of current influenza A(H1N1)pdm09 and A(H3N2) viruses that are circulating in the human population. This method is based on the estimation of virus reproduction in infected MDCK cells. The detection step of this method is an interaction of the subtype-specific monoclonal antibodies (mAbs) with the viral hemagglutinin (НА) molecule. The influenza A virus strains, isolated in the 2014 epidemic season, were used to validate this method.It was shown that when using mAbs # 1/ # 2 or # 4 at a concentration of 10-15 µg/ml, the developed variant of cell-ELISA was able to detect НА protein synthesized in the infected cells of influenza A(H3N2) and A(H1N1)pdm09 viruses, respectively.The developed method can be used for the identification of modern influenza A viruses with low hemagglutination activity, which is not possible by the conventional hemagglutination inhibition test.The sensitive version of cell-ELISA was developed for the subtype-specific differentiation of current influenza A(H1N1)pdm09 and A(H3N2) viruses that are circulating in the human population. This method is based on the estimation of virus reproduction in infected MDCK cells. The detection step of this method is an interaction of the subtype-specific monoclonal antibodies (mAbs) with the viral hemagglutinin (НА) molecule. The influenza A virus strains, isolated in the 2014 epidemic season, were used to validate this method. It was shown that when using mAbs # 1/ # 2 or # 4 at a concentration of 10-15 µg/ml, the developed variant of cell-ELISA was able to detect НА protein synthesized in the infected cells of influenza A(H3N2) and A(H1N1)pdm09 viruses, respectively. The developed method can be used for the identification of modern influenza A viruses with low hemagglutination activity, which is not possible by the conventional hemagglutination inhibition test