548 research outputs found

    On Brand: Communication Center Tutors as Social Media Content Creators

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    Because social media is a significant factor in how students and faculty in higher education engage with the world, it is important for communication centers to consider this medium as a method to meet those audiences where they are. While there are challenges to creating a social media presence, this article argues that engaging your tutors in both developing your communication center’s branding strategy and as content creators will help you address those challenges. Building your communication center’s social media presence offers you not just an avenue to communicate the core values of your center to your institution, it is also an opportunity to develop your tutoring staff’s intellectual engagement and enhance their professionalization.

    Mortgages--The Doctrine of Future Advances

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    Torts--The Fall of the Charitable Immunity Doctrine

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    Molecular patterning mechanism underlying metamorphosis of the thoracic leg in Manduca sexta

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    AbstractThe tobacco hornworm Manduca sexta, like many holometabolous insects, makes two versions of its thoracic legs. The simple legs of the larva are formed during embryogenesis, but then are transformed into the more complex adult legs at metamorphosis. To elucidate the molecular patterning mechanism underlying this biphasic development, we examined the expression patterns of five genes known to be involved in patterning the proximal–distal axis in insect legs. In the developing larval leg of Manduca, the early patterning genes Distal-less and Extradenticle are already expressed in patterns comparable to the adult legs of other insects. In contrast, Bric-a-brac and dachshund are expressed in patterns similar to transient patterns observed during early stages of leg development in Drosophila. During metamorphosis of the leg, the two genes finally develop mature expression patterns. Our results are consistent with the hypothesis that the larval leg morphology is produced by a transient arrest in the conserved adult leg patterning process in insects. In addition, we find that, during the adult leg development, some cells in the leg express the patterning genes de novo suggesting that the remodeling of the leg involves changes in the patterning gene regulation

    Nitric Oxide and Cyclic GMP Regulate Retinal Patterning in the Optic Lobe of Drosophila

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    AbstractThe photoreceptors of Drosophila express a nitric oxide–sensitive guanylate cyclase during the first half of metamorphosis, when postsynaptic elements in the optic lobe are being selected. Throughout this period, the optic lobes show NADPH-diaphorase activity and stain with an antibody to nitric oxide synthase (NOS). The NOS inhibitor L-NAME, the NO scavenger PTIO, the sGC inhibitor ODQ, and methylene blue, which inhibits NOS and guanylate cyclase, each caused the disorganization of retinal projections and extension of photoreceptor axons beyond their normal synaptic layers in vitro. The disruptive effects of L-NAME were prevented with the addition of 8-bromo-cGMP. These results suggest NO and cGMP act to stabilize retinal growth cones at the start of synaptic assembly

    Hopf-Galois Module Structure Of Some Tamely Ramified Extensions

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    We study the Hopf-Galois module structure of algebraic integers in some finite extensions of p p -adic fields and number fields which are at most tamely ramified. We show that if L/K L/K is a finite unramified extension of p p -adic fields which is Hopf-Galois for some Hopf algebra H H then the ring of algebraic integers \OL is a free module of rank one over the associated order \AH . If H H is a commutative Hopf algebra, we show that this conclusion remains valid in finite ramified extensions of p p -adic fields if p p does not divide the degree of the extension. We prove analogous results for finite abelian Galois extensions of number fields, in particular showing that if L/K L/K is a finite abelian domestic extension which is Hopf-Galois for some commutative Hopf algebra H H then \OL is locally free over \AH . We study in greater detail tamely ramified Galois extensions of number fields with Galois group isomorphic to Cp×Cp C_{p} \times C_{p} , where p p is a prime number. Byott has enumerated and described all the Hopf-Galois structures admitted by such an extension. We apply the results above to show that \OL is locally free over \AH in all of the Hopf-Galois structures, and derive necessary and sufficient conditions for \OL to be globally free over \AH in each of the Hopf-Galois structures. In the case p=2 p = 2 we consider the implications of taking K = \Q . In the case that p p is an odd prime we compare the structure of \OL as a module over \AH in the various Hopf-Galois structures.Engineering And Physical Sciences Research Counci
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