Hazing: What Ohio High School Teachers, Coaches and Administrators Need to Know

Once thought to be primarily an issue of concern for university fraternities and sororities, hazing has emerged as a disturbing trend with an increase in the number of incidents involving high school student athletes. High school coaches, athletic administrators, and teachers must understand that initiation rites of sport teams can sometimes spiral out of control with grave legal and financial consequences for student athletes and school officials. The purposes of this article are to: Define hazing and review the history of anti-hazing legislation in the United States of America. Describe hazing laws in the State of Ohio. Review current research related to hazing specifically at the high school level. Discuss proactive strategies coaches, administrators, students, teachers, parents, and the community can use to prevent the harmful practices of hazing

General Conditions for Proximity-Induced Odd-Frequency Superconductivity in Two-Dimensional Electronic Systems

We obtain the general conditions for the emergence of odd-frequency superconducting pairing in a two-dimensional (2D) electronic system proximity coupled to a superconductor, making minimal assumptions about both the 2D system and the superconductor. Using our general results we show that a simple heterostructure formed by a monolayer of a group VI transition metal dichalcogenide, such as molybdenum disulfide, and an s-wave superconductor with Rashba spin-orbit coupling exhibits odd-frequency superconducting pairing. Our results allow the identification of a new class of systems among van der Waals heterostructures in which odd-frequency superconductivity should be present

High affinity immobilization of proteins using the CrAsH/TC tag

Protein microarrays represent important tools for biomedical analysis. We have recently described the use of the biarsenical-tetracysteine (TC) tag for the preparation of protein microarrays. The unique feature of this tag enables the site-specific immobilization of TC-containing proteins on biarsenical-modified surfaces, resulting in a fluorescence enhancement that allows the direct quantification of the immobilized proteins. Moreover, the reversibility of the binding upon incubation with large quantities of thiols permits the detachment of the proteins from the surface, thereby enabling recovery of the substrate to extend the life time of the slide. Herein, we describe our recent results that further extend the applicability of the CrAsH/TC tag to the fabrication of biochips. With this aim, the immobilization of proteins on surfaces has been investigated using two different spacers and two TC tags, the minimal TC sequence (CCPGCC) and an optimized motif (FLNCCPGCCMEP). While the minimal peptide motif enables a rapid recycling of the slide, the optimized TC sequence reveals an increased affinity due to its greater resistance to displacement by thiols. Moreover, the developed methodology was applied to the immobilization of proteins via on-chip ligation of recombinant protein thioesters