726 research outputs found

    Constitutional Law - Fifth and Fourteenth Amendments - Privilege Against Self-Incrimination - Procedure in State Criminal Trials - Jury Instructions

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    The Supreme Court of the United States has held that a state criminal trial judge has a constitutional obligation, on a defendant\u27s request, to instruct a jury that no inference of guilt may be drawn from a defendant\u27s failure to testify. Carter v. Kentucky, 101 S. Ct. 1112 (1981)

    Wind-tunnel tests on a 3-dimensional fixed-geometry scramjet inlet at M = 2.30 to 4.60

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    Wind-tunnel tests were conducted on a baseline scramjet inlet model having fixed geometry and swept leading edges at M = 2.30, 2.96, 3.95, and 4.60 in the Langley unitary plan wind tunnel. The unit Reynolds number of the tests was held constant at 6.56 million per meter (2 million per foot). The objectives of the tests were to establish inlet performance and starting characteristics in the lower Mach number range of operation (less than M = 5). Surface pressures obtained on the inlet components are presented, along with the results of the internal flow surveys made at the throat and capture stations of the inlet. Contour plots of the inlet-flow-field parameters such as Mach numbers, pressure recovery, flow capture, local static and total pressure ratios at the survey stations are shown for the test Mach numbers

    Microwave radiometric studies and ground truth measurements of the NASA/USGS Southern California test site

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    The field measurement program conducted at the NASA/USGS Southern California Test Site is discussed. Ground truth data and multifrequency microwave brightness data were acquired by a mobile field laboratory operating in conjunction with airborne instruments. The ground based investigations were performed at a number of locales representing a variety of terrains including open desert, cultivated fields, barren fields, portions of the San Andreas Fault Zone, and the Salton Sea. The measurements acquired ground truth data and microwave brightness data at wavelengths of 0.8 cm, 2.2 cm, and 21 cm

    Lunar navigation study, volume 2 Final report, Jan. - Dec. 1966

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    Performance data utilization in mission phase, lunar exploration phase, and navigational phase of lunar roving vehicle mission

    LANDSAT-1 data as it has been applied for land use and water quality data by the Virginia State Water Control Board. 1: The state project. 2: Monitoring water quality from LANDSAT

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    LANDSAT-1 imagery has been used for water quality and land use monitoring in and around the Swift Creek and Lake Chesdin Reservoirs in Virginia. This has proved useful by (1) helping determine valid reservoir sampling stations, (2) monitoring areas not accessible by land or water, (3) giving the State a viable means of measuring Secchi depth readings in these inaccessible areas, (4) giving an overview of trends in changing sedimentation loadings over a given time period and classifying these waters into various categories, (5) enabling the State to inventory all major lakes and reservoirs and computing their acreage, (6) monitoring land use changes in any specific area, (7) evaluating possible long-term environmental effects of nearby developments, and (8) monitoring and predicting population shifts with possible impact on water quality problems. The main problems in the long-term use of such imagery appear to be cost and lack of consistency due to cloud cover limitations

    A Case Study Analysis about the Use of a Digital Transition Portfolio for Secondary Students with Mild to Moderate Disabilities in an Urban Inclusive High School Classroom

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    This qualitative single case study examined how one teacher used a digital portfolio in an inclusive urban high school career research and development (CRD) class over one semester. Specifically, this research described a) the teacherā€™s perceptions of the use of a digital portfolio for secondary transition; b) how the digital portfolio was used in conjunction with a curriculum for secondary transition; c) the relation between a digital portfolio and curricular content; and d) how the relationships among the digital portfolio, curricular content, and instruction varied for students with disabilities. Data were collected using semi-structured interviews, participant and passive observation, document analysis/physical artifacts, and field notes. Coding was used in the final analyses. The results revealed the digital portfolio was defined by the purpose, creation, selection of activities, and ongoing development. Overall, digital portfolio development benefited the teacher and his students. Studentsā€™ portfolio content helped the teacher identify conceptual understandings, and errors. The digital portfolio was a useful tool for use in a high school transition class. Themes that emerged in the analysis were related to time commitment, availability of digitized materials, and insuring that materials/activities were both appropriate for the digital portfolio and supported student learning goals. Results indicated how the strategic use of technology can facilitate the transition experience for young adults with disabilities. Barriers related to using the digital portfolio were teacher time, computer accessibility, digitalization, and situational factors. Implications for practice, contributions to the research base, and future research are discussed

    Single-channel SCAM Identifies Pore-lining Residues in the First Extracellular Loop and First Transmembrane Domains of Cx46 Hemichannels

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    Gap junction (GJ) channels provide an important pathway for direct intercellular transmission of signaling molecules. Previously we showed that fixed negative charges in the first extracellular loop domain (E1) strongly influence charge selectivity, conductance, and rectification of channels and hemichannels formed of Cx46. Here, using excised patches containing Cx46 hemichannels, we applied the substituted cysteine accessibility method (SCAM) at the single channel level to residues in E1 to determine if they are pore-lining. We demonstrate residues D51, G46, and E43 at the amino end of E1 are accessible to modification in open hemichannels to positively and negatively charged methanethiosulfonate (MTS) reagents added to cytoplasmic or extracellular sides. Positional effects of modification along the length of the pore and opposing effects of oppositely charged modifying reagents on hemichannel conductance and rectification are consistent with placement in the channel pore and indicate a dominant electrostatic influence of the side chains of accessible residues on ion fluxes. Hemichannels modified by MTS-EA+, MTS-ET+, or MTS-ESāˆ’ were refractory to further modification and effects of substitutions with positively charged residues that electrostatically mimicked those caused by modification with the positively charged MTS reagents were similar, indicating all six subunits were likely modified. The large reductions in conductance caused by MTS-ET+ were visible as stepwise reductions in single-channel current, indicative of reactions occurring at individual subunits. Extension of single-channel SCAM using MTS-ET+ into the first transmembrane domain, TM1, revealed continued accessibility at the extracellular end at A39 and L35. The topologically complementary region in TM3 showed no evidence of reactivity. Structural models show GJ channels in the extracellular gap to have continuous inner and outer walls of protein. If representative of open channels and hemichannels, these data indicate E1 as constituting a significant portion of this inner, pore-forming wall, and TM1 contributing as pore-lining in the extracellular portion of transmembrane span
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