On the Linearization of the Painleve' III-VI Equations and Reductions of the Three-Wave Resonant System

We extend similarity reductions of the coupled (2+1)-dimensional three-wave resonant interaction system to its Lax pair. Thus we obtain new 3x3 matrix Fuchs--Garnier pairs for the third and fifth Painleve' equations, together with the previously known Fuchs--Garnier pair for the fourth and sixth Painleve' equations. These Fuchs--Garnier pairs have an important feature: they are linear with respect to the spectral parameter. Therefore we can apply the Laplace transform to study these pairs. In this way we found reductions of all pairs to the standard 2x2 matrix Fuchs--Garnier pairs obtained by M. Jimbo and T. Miwa. As an application of the 3x3 matrix pairs, we found an integral auto-transformation for the standard Fuchs--Garnier pair for the fifth Painleve' equation. It generates an Okamoto-like B\"acklund transformation for the fifth Painleve' equation. Another application is an integral transformation relating two different 2x2 matrix Fuchs--Garnier pairs for the third Painleve' equation.Comment: Typos are corrected, journal and DOI references are adde

Homenaje al doctor Bernardo A. Houssay 1887-1971

Reseña de la vida de Houssay en sus distintos aspectos, escrita por tres de sus discípulos. Contenido: "In memoriam" por Luis Leloir (p. 3-4).- "Bernardo Alberto Houssay (1887-1971)", por Virgilio G. Foglia (p.5- 40).- "Bernardo A. Houssay: el hombre, el investigador, el impulsor del desarrollo científico nacional", por Juan T. Lewis (p.42-47)Fil: Leloir, Luis Federico. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundacion Campomar; ArgentinaFil: Foglia, Virgilio G.. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Lewis, Juan Treharne. Universidad Nacional del Litoral; ArgentinapapelKofax Power v.3.1Fujitsu ScanSnap SV600Directivos BAHUnidad documental simpleBiblioteca Bernardo A. Houssay-0

Fisiología humana

El libro está dedicado a la memoria de Juan Sauberan y a la Fundación Sauberán por sus obras en favor de la investigación científica original. El prólogo escrito por Bernardo Houssay, indica que está destinado a los estudiantes de medicina y médicos para instruirse, en idioma castellano, en los principios fundamentales de la fisiología moderna. Comprende fisiología humana, general y comparada. Hace referencia a la importancia de la fisiología general, que se nutre de la medicina experimental. Los hallazgos de la fisiología clínica se asientan en el conocimiento de la fisiología. Se refiere a la enseñanza, a la necesidad de desarrollar el espíritu científico, complementando el estudio de contenidos con prácticas didácticas y rigurosas, generando interés en el estudiante. Explica la forma en que está organizada la obra, que se basa en información de todos los países e idiomas y de la propia Escuela de Houssay; en la medida de lo posible los temas van acompañados de demostraciones que obligan al análisis crítico, da importancia a la bibliografía y agrega bibliografía ampliatoria al final de cada tema.Cada sección fue escrita por un autor destacado: Braun Menéndez, E.: Digestión. Secreción urinaria. Ejercicio y trabajo; Foglia, V.G.: Audición. Fonación y palabra. Reflejos condicionales; Houssay, B. A. : Sangre. Metabolismo. Secreciones internas. Reproducción. Sueño. Electroencefalografía. Evolución e integración del organismo; Hug, E.: Respiración; Lewis, J. T. : Sistema nervioso y músculo; Orías, O. : Circulación. Visión. Herencia.La primera edición del libro es de 1945 y al agotarse, fue necesario hacer una reimpresión. En el año 1946 fue traducido al francés e inglés. Luego a otros idiomas como el italiano, alemán, portugués. Con las nuevas ediciones fueron actualizándose los contenidos e incorporándose nuevos co-autores como L. F. Leloir, J.C. Fasciolo, M.R.; Covián; Alberto B. Houssay; R. Caldeyro-Barcia; M. L. de Soldati, entre muchos otros.Fisiología Humana fue utilizado en las universidades durante mas de cincuenta años, con él se formaron generaciones de médicos argentinos y de otros países, por lo cual es considerado un libro clásico dentro de la enseñanza de la Medicina.derivadaFil: Houssay, Bernardo Alberto. Fundación de Instituto de Biología y Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina; ArgentinaFil: Lewis, Juan Treharne.Fil: Orías, Oscar.Fil: Hug, Enrique.Fil: Braun Menéndez, Eduardo. Fundación de Instituto de Biología y Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina; ArgentinaFil: Foglia, Virgilio G.. Fundación de Instituto de Biología y Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentinail. ; graf.; tablas; fotografías. Encuadernado cuerina.Parte de este libro fue digitalizado con fines exclusivos de estudio e investigación. Se incluyen las portadas, páginas preliminares, primeros capítulos e índices. Se ofrece un acercamiento a su contenido, a la organización y al tratamiento de los temas con la sección I. La Sección II y subsiguientes no forman parte de esta versión digital.papelKofax Power v.3.1: ScanTailor advancedFujitsu ScanSnap SV600FormaciónUnidad documental simpleBiblioteca Bernardo A. Houssay-0

‘We’ll be okay together’: navigating challenges as queer university students in Aotearoa New Zealand

Queer university students face multiple stressors which can contribute to mental health difficulties, including minority stressors unique to their queer identities. However, there is little literature exploring stressors faced by queer individuals in university settings. The aim of this study was to qualitatively explore the current challenges and strengths faced by queer university students in Aotearoa New Zealand, in order to contextualise their mental health experiences. Twenty-eight queer students participated across 12 focus groups or interviews. Two queer researchers thematically analysed the data. Three themes were interpreted from the data: ‘That’s not feminine enough’: the impact of societal ideologies on queer students; ‘There’s one rainbow person in the room’: Tokenism, social isolation, and then finding community; and ‘You know what it’s like to not be heard’: The transformation of challenges into strengths. The findings illustrate how queer university students make meaning of their challenges, and the strengths they develop to mitigate these. Educational institutions are highlighted as important sites of systemic change, to reduce minority stressors in students’ lives

The cystic fibrosis transmembrane recruiter the alter ego of CFTR as a multi-kinase anchor

This review focuses on a newly discovered interaction between protein kinases involved in cellular energetics, a process that may be disturbed in cystic fibrosis for unknown reasons. I propose a new model where kinase-mediated cellular transmission of energy provides mechanistic insight to a latent role of the cystic fibrosis transmembrane conductance regulator (CFTR). I suggest that CFTR acts as a multi-kinase recruiter to the apical epithelial membrane. My group finds that, in the cytosol, two protein kinases involved in cell energy homeostasis, nucleoside diphosphate kinase (NDPK) and AMP-activated kinase (AMPK), bind one another. Preliminary data suggest that both can also bind CFTR (function unclear). The disrupted role of this CFTR-kinase complex as ‘membrane transmitter to the cell’ is proposed as an alternative paradigm to the conventional ion transport mediated and CFTR/chloride-centric view of cystic fibrosis pathogenesis. Chloride remains important, but instead, chloride-induced control of the phosphohistidine content of one kinase component (NDPK, via a multi-kinase complex that also includes a third kinase, CK2; formerly casein kinase 2). I suggest that this complex provides the necessary near-equilibrium conditions needed for efficient transmission of phosphate energy to proteins controlling cellular energetics. Crucially, a new role for CFTR as a kinase controller is proposed with ionic concentration acting as a signal. The model posits a regulatory control relay for energy sensing involving a cascade of protein kinases bound to CFTR

Accelerated optimization of transparent, amorphous zinc-tin-oxide thin films for optoelectronic applications

In the last decade, transparent amorphous oxide semiconductors (TAOS) have become an essential component of many electronics, from ultra high resolution displays to solar cells. However, these disordered oxides typically rely on expensive component metals like indium to provide sufficient charge carrier conduction, and their optoelectronic properties are not as predictable and well-described as those of traditional, crystalline semiconductors. Herein we report on our comprehensive study of the amorphous zinc-tin-oxide (a-ZTO) system for use as an indium-free, n-type TAOS. Using a combination of high-throughput co-deposition growth, high resolution spectral mapping, and atomistic calculations, we explain the development of disorder-related subgap states in SnO2-like a-ZTO and optical bandgap reduction in ZnO-like a-ZTO. In addition, we report on a composition-induced electronic and structural transition in ZnO-like a-ZTO resulting in an exceptionally high figure of merit, comparable to that of amorphous indium-gallium-zinc-oxide. Our results accelerate the development of a-ZTO and similar systems as indium-free TAOS materials

Depression and anxiety in patients with rheumatoid arthritis: prevalence rates based on a comparison of the Depression, Anxiety and Stress Scale (DASS) and the hospital, Anxiety and Depression Scale (HADS)

<p>Abstract</p> <p>Background</p> <p>While it is recognised that depression is prevalent in Rheumatoid Arthritis (RA), recent studies have also highlighted significant levels of anxiety in RA patients. This study compared two commonly used scales, the Depression Anxiety and Stress Scale (DASS) and the Hospital Anxiety and Depression Scale (HADS), in relation to their measurement range and cut points to consider the relative prevalence of both constructs, and if prevalence rates may be due to scale-specific case definition.</p> <p>Methods</p> <p>Patients meeting the criteria for RA were recruited in Leeds, UK and Sydney, Australia and asked to complete a survey that included both scales. The data was analysed using the Rasch measurement model.</p> <p>Results</p> <p>A total of 169 RA patients were assessed, with a repeat subsample, resulting in 323 cases for analysis. Both scales met Rasch model expectations. Using the 'possible+probable' cut point from the HADS, 58.3% had neither anxiety nor depression; 13.5% had anxiety only; 6.4% depression only and 21.8% had both 'possible+probable' anxiety and depression. Cut points for depression were comparable across the two scales while a lower cut point for anxiety in the DASS was required to equate prevalence.</p> <p>Conclusions</p> <p>This study provides further support for high prevalence of depression and anxiety in RA. It also shows that while these two scales provide a good indication of possible depression and anxiety, the estimates of prevalence so derived could vary, particularly for anxiety. These findings are discussed in terms of comparisons across studies and selection of scales for clinical use.</p