Parsing Speech: A Neural Approach to Integrating Lexical and Acoustic-Prosodic Information

In conversational speech, the acoustic signal provides cues that help listeners disambiguate difficult parses. For automatically parsing spoken utterances, we introduce a model that integrates transcribed text and acoustic-prosodic features using a convolutional neural network over energy and pitch trajectories coupled with an attention-based recurrent neural network that accepts text and prosodic features. We find that different types of acoustic-prosodic features are individually helpful, and together give statistically significant improvements in parse and disfluency detection F1 scores over a strong text-only baseline. For this study with known sentence boundaries, error analyses show that the main benefit of acoustic-prosodic features is in sentences with disfluencies, attachment decisions are most improved, and transcription errors obscure gains from prosody.Comment: Accepted in NAACL HLT 201

Urinary Phthalate Metabolites and Biomarkers of Oxidative Stress in a Mexican-American Cohort: Variability in Early and Late Pregnancy.

People are exposed to phthalates through their wide use as plasticizers and in personal care products. Many phthalates are endocrine disruptors and have been associated with adverse health outcomes. However, knowledge gaps exist in understanding the molecular mechanisms associated with the effects of exposure in early and late pregnancy. In this study, we examined the relationship of eleven urinary phthalate metabolites with isoprostane, an established marker of oxidative stress, among pregnant Mexican-American women from an agricultural cohort. Isoprostane levels were on average 20% higher at 26 weeks than at 13 weeks of pregnancy. Urinary phthalate metabolite concentrations suggested relatively consistent phthalate exposures over pregnancy. The relationship between phthalate metabolite concentrations and isoprostane levels was significant for the sum of di-2-ethylhexyl phthalate and the sum of high molecular weight metabolites with the exception of monobenzyl phthalate, which was not associated with oxidative stress at either time point. In contrast, low molecular weight metabolite concentrations were not associated with isoprostane at 13 weeks, but this relationship became stronger later in pregnancy (p-value = 0.009 for the sum of low molecular weight metabolites). Our findings suggest that prenatal exposure to phthalates may influence oxidative stress, which is consistent with their relationship with obesity and other adverse health outcomes

Primary Lung Carcinoid Metastatic to the Breast

Lung carcinoid tumors account for approximately 2% of lung cancers, with 10% of the tumors represented by the atypical type. While atypical carcinoids are metastatic to intrathoracic lymph nodes in approximately half of the cases on the initial presentation, distant metastases are seen in only 20% of the patients and are found most frequently in bones, liver, adrenal glands, and brain. We present a case of an unusual metastatic disease to the breast in 51-year-old female who developed a new breast mass 2 years after left lower lobectomy due to atypical carcinoid tumor. Atypical pulmonary carcinoid metastases to the breast are exceptionally uncommon, yet they are important considerations for appropriate management, especially with an anamnesis of this neoplasm

Integrating certifications into the cybersecurity college curriculum: The efficacy of education with certifications to increase the cybersecurity workforce

One only needs to listen to the news reports to recognize that the gap between securing the enterprise and cybersecurity threats, breaches, and vulnerabilities appears to be widening at an alarming rate. An un-tapped resource to combat these attacks lies in the students of the secondary educational system. Necessary in the cybersecurity education is a 3-tiered approach to quickly escalate the student into a workplace-ready graduate. The analogy used is a three-legged-stool, where curriculum content, hands-on skills, and certifications are equal instruments in the edification of the cybersecurity student. This paper endeavors to delve into the 3rd leg of the stool by developing the concept of vendor-specific and vendor-neutral certifications to educate the cybersecurity student and test their capability of protecting the workplace. The research data was drawn from companies in the Atlanta, Georgia area, who employ and hire cybersecurity recruits. The data from the research proves certifications are necessary as an addition to the cybersecurity curriculum in the secondary education arena. The paper reviews the need for cybersecurity graduates, the balance between cybersecurity theory and applied skillsets, the difference between a certificate and a certification, benefits to the community, classifications of certifications, relevancy of a college degree in today’s workforce, and recommendations for further study

Electronic Payment Systems – Payment Gateways and Data Security Standards

The use of mobile applications has allowed electronic transactions to be made anytime, anywhere, and by anyone. The Internet has made it possible for businesses to expand their reach across the globe. As a guiding agent for purchasing decisions, social media’s proliferation has expanded businesses’ ability to generate revenue [1]. In short, e-commerce has become a mainstay in the way consumers shop. The findings related to this study are three-fold. First, a systematic and rigorous approach is applied to research the importance of Payment Gateways and the Payment Card Industry Data Security Standards in today’s electronic marketplace. Next, a quantitative survey was administered to college-level students to validate the need to expand the course curriculum. Lastly, suggestions for future studies are provided to help bridge the gap between academia and the corporate world. When combined, this information will equip students with the needed knowledge to succeed when they enter the e-commerce workforce. Keywords: Payment Gateways, Data Security Standards, Electronic Payment Systems DOI: 10.7176/JEP/12-3-21 Publication date: January 31st 2021

Bleeding Stomal Varices in Portal Hypertension

We report a case of a 50-year-old man with a history of liver cirrhosis and colon cancer post end colostomy presenting to the emergency department with stomal bleeding and passage of clots into the colostomy bag. The patient was treated with transjugular intrahepatic portosystemic shunt (TIPS) and concomitant embolization of the stomal varices via the TIPS shunt using N-butyl cyanoacrylate mixed with ethiodol. Although stomal variceal bleeding is uncommon, this entity can have up to 40% mortality upon initial presentation, given the challenges in diagnosis and management. Currently, there are no established standard treatments for stomal variceal bleeding. In addition, to the best of our knowledge, there are no cases in the current literature in which treatment of this entity is performed with a combination of TIPS shunt placement and N-butyl cyanoacrylate variceal embolization

Renal Granulomatosis Post Intravesical Bacillus Calmette-Guerin Therapy for Non-Muscle-Invasive Bladder Cancer

Intravesical Bacillus Calmette–Guerin (BCG) immunotherapy is a proven, effective treatment for intermediate- and high-risk non-muscle-invasive bladder cancer. Minor side effects are common and expected but systemic effects can occur in \u3c 5% of treated patients. We present a rare case of a 49-year-old male that presented with fever and chills after 3 weeks of intravesical BCG therapy post transurethral resection of bladder tumor. New renal lesions were present on contrast-enhanced computed tomography scan which was histologically proven to be necrotizing renal granulomatosis

Preventing postnatal maternal mental health problems using a psychoeducational intervention : the cost-effectiveness of What Were We Thinking

OBJECTIVES: Postnatal maternal mental health problems, including depression and anxiety, entail a significant burden globally, and finding cost-effective preventive solutions is a public policy priority. This paper presents a cost-effectiveness analysis of the intervention, What Were We Thinking (WWWT), for the prevention of postnatal maternal mental health problems. DESIGN: The economic evaluation, including cost-effectiveness and cost-utility analyses, was conducted alongside a cluster-randomised trial. SETTING: 48 Maternal and Child Health Centres in Victoria, Australia. PARTICIPANTS: Participants were English-speaking first-time mothers attending participating Maternal and Child Health Centres. Full data were collected for 175 participants in the control arm and 184 in the intervention arm. INTERVENTION: WWWT is a psychoeducational intervention targeted at the partner relationship, management of infant behaviour and parental fatigue. OUTCOME MEASURES: The evaluation considered public sector plus participant out-of-pocket costs, while outcomes were expressed in the 30-day prevalence of depression, anxiety and adjustment disorders, and quality-adjusted life years (QALYs). Incremental costs and outcomes were estimated using regression analyses to account for relevant sociodemographic, prognostic and clinical characteristics. RESULTS: The intervention was estimated to cost $A118.16 per participant. The analysis showed no statistically significant difference between the intervention and control groups in costs or outcomes. The incremental cost-effectiveness ratios were$A36 451 per QALY gained and $A152 per percentage-point reduction in 30-day prevalence of depression, anxiety and adjustment disorders. The estimate lies under the unofficial cost-effectiveness threshold of$A55 000 per QALY; however, there was considerable uncertainty surrounding the results, with a 55% probability that WWWT would be considered cost-effective at that threshold. CONCLUSIONS: The results suggest that, although WWWT shows promise as a preventive intervention for postnatal maternal mental health problems, further research is required to reduce the uncertainty over its cost-effectiveness as there were no statistically significant differences in costs or outcomes. TRIAL REGISTRATION NUMBER: ACTRN12613000506796; results

Aerosol Generating Procedures and Risk of Transmission of Acute Respiratory Infections to Healthcare Workers: A Systematic Review

Aerosol generating procedures (AGPs) may expose health care workers (HCWs) to pathogens causing acute respiratory infections (ARIs), but the risk of transmission of ARIs from AGPs is not fully known. We sought to determine the clinical evidence for the risk of transmission of ARIs to HCWs caring for patients undergoing AGPs compared with the risk of transmission to HCWs caring for patients not undergoing AGPs. We searched PubMed, EMBASE, MEDLINE, CINAHL, the Cochrane Library, University of York CRD databases, EuroScan, LILACS, Indian Medlars, Index Medicus for SE Asia, international health technology agencies and the Internet in all languages for articles from 01/01/1990 to 22/10/2010. Independent reviewers screened abstracts using pre-defined criteria, obtained full-text articles, selected relevant studies, and abstracted data. Disagreements were resolved by consensus. The outcome of interest was risk of ARI transmission. The quality of evidence was rated using the GRADE system. We identified 5 case-control and 5 retrospective cohort studies which evaluated transmission of SARS to HCWs. Procedures reported to present an increased risk of transmission included [n; pooled OR(95%CI)] tracheal intubation [n = 4 cohort; 6.6 (2.3, 18.9), and n = 4 case-control; 6.6 (4.1, 10.6)], non-invasive ventilation [n = 2 cohort; OR 3.1(1.4, 6.8)], tracheotomy [n = 1 case-control; 4.2 (1.5, 11.5)] and manual ventilation before intubation [n = 1 cohort; OR 2.8 (1.3, 6.4)]. Other intubation associated procedures, endotracheal aspiration, suction of body fluids, bronchoscopy, nebulizer treatment, administration of O2, high flow O2, manipulation of O2 mask or BiPAP mask, defibrillation, chest compressions, insertion of nasogastric tube, and collection of sputum were not significant. Our findings suggest that some procedures potentially capable of generating aerosols have been associated with increased risk of SARS transmission to HCWs or were a risk factor for transmission, with the most consistent association across multiple studies identified with tracheal intubation