Oropharyngeal colonization by nontypeable Haemophilus influenzae among healthy children attending day care centers

Haemophilus influenzae colonizes the upper respiratory tract and can spread causing otitis and sinusitis. This work aimed to study the oropharyngeal carriage rate in healthy <5-year-old children attending day care centers in Oviedo, Spain in two consecutive years (January to March 2004-2005). The carriage rate was 42% (400/960) and highly variable among centers (range, 12% to 83%). Isolates were mainly identified as nontypeable H. influenzae (NTHi, 99%). Epidemiologically, 127 different genotypes were identified by PFGE with a minimum of two genotypes per center. One hundred fourteen children (12%) were included in both studies and none of them harbored the same strain over a period of time. The isolates only showed resistance to cotrimoxazol and ampicillin, presenting a shift in the level of ampicillin reduced susceptibility, showing a predominance of PBP3 mutations in 2004 and a predominance of β-lactamase production in 2005. This study proved the great genetic variability of NTHi isolates that present similar genotypic patterns in both years with no long-term carriage of the same strain

Predictors of Response to Exclusive Enteral Nutrition in Newly Diagnosed Crohn´s Disease in Children: PRESENCE Study from SEGHNP

Exclusive enteral nutrition (EEN) has been shown to be more effective than corticosteroids in achieving mucosal healing in children with Crohn´s disease (CD) without the adverse effects of these drugs. The aims of this study were to determine the efficacy of EEN in terms of inducing clinical remission in children newly diagnosed with CD, to describe the predictive factors of response to EEN and the need for treatment with biological agents during the first 12 months of the disease. We conducted an observational retrospective multicentre study that included paediatric patients newly diagnosed with CD between 2014–2016 who underwent EEN. Two hundred and twenty-two patients (140 males) from 35 paediatric centres were included, with a mean age at diagnosis of 11.6 ± 2.5 years. The median EEN duration was 8 weeks (IQR 6.6–8.5), and 184 of the patients (83%) achieved clinical remission (weighted paediatric Crohn’s Disease activity index [wPCDAI] 15 mg/L and ileal involvement tended to respond better to EEN. EEN administered for 6–8 weeks is effective for inducing clinical remission. Due to the high response rate in our series, EEN should be used as the first-line therapy in luminal paediatric Crohn’s disease regardless of the location of disease and disease activityS

Revista galega do ensino

Resumen basado en el de la publicaciónEl estilo de vida actual favorece cambios en los hábitos dietéticos de los niños y el consumo de alimentos altamente energéticos, desplazando a otros hábitos más saludables. El modelo de estructura familiar, la influencia de la televisión, la incorporación temprana a la escuela y la disponibilidad para comprar alimentos manufacturados que consumen sin control favorecen un ambiente obesogénico. Por tanto, se hace necesario establecer tempranamente en el niño hábitos dietéticos saludables con repercusiones positivas sobre el estado de bienestar y que favorezcan la reducción del riesgo de enfermedad.GaliciaBiblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín, 5 - 3 Planta; 28014 Madrid; Tel. +34917748000; [email protected]

Revista galega do ensino

Resumen basado en el de la publicaciónLa obesidad es una de las enfermedades crónicas más prevalentes lo que ocasiona una alta tasa de morbimortalidad y un alto coste sanitario y social. La obesidad se asocia desde la niñez a procesos y enfermedades que afectan a la mayoría de órganos y sistemas. Por ello es necesaria una actuación temprana en la prevención del desarrollo de factores de riesgo. Asimismo, la prevención debe dirigirse a mejorar las estrategias conductuales y realizarse en el marco de la familia y la escuela y para ello se presentan una serie de líneas de acción.GaliciaBiblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín, 5 - 3 Planta; 28014 Madrid; Tel. +34917748000; [email protected]