Search for Supersymmetrie using Multileptonic Signatures in Proton-Proton Collisions with the CMS Detector at the LHC

A search for mutlileptonic signatures with three or more isolated leptons in pp collisions at sqrt(s)=7 TeV is presented in this Thesis. The data, recorded with the CMS experiment at the LHC in 2011 , corresponds to an integrated luminosity of 4.7 fb^-1. The observed multilepton events are categorized into exclusive search channels based on the identity and kinematics of the objects and the events. The search results are interpreted in the context of R-parity conserving supersymmetric models

Quantum-limited measurements of optical signals from a geostationary satellite

The measurement of quantum signals that traveled through long distances is of fundamental and technological interest. We present quantum-limited coherent measurements of optical signals, sent from a satellite in geostationary Earth orbit to an optical ground station. We bound the excess noise that the quantum states could have acquired after having propagated 38600 km through Earth's gravitational potential as well as its turbulent atmosphere. Our results indicate that quantum communication is feasible in principle in such a scenario, highlighting the possibility of a global quantum key distribution network for secure communication.Comment: 8 pages (4 pages main article, 4 pages supplementary material), 9 figures (4 figures main article, 5 figures supplementary material), Kevin G\"unthner and Imran Khan contributed equally to this wor

The TDP-1 Mission Control Center and ist current operational experience

TDP-1 is a quasi-operational technology demonstration payload, designed to prove the concept of data transfer between low-orbit observation satellites and earth via a geostationary relay satellite in between the communication chain. This detour allows to significantly increase transferable data volume at reduced latency time, and is performed with the help of Laser Communication Terminals (LCTs) on board the low-orbit as well as the geostationary satellite, from which the data is immediately downlinked via Ka-Band. In this framework, TDP-1 is the successful precursor mission for the forthcoming European Data Relay Satellite System (EDRS). A dedicated operational concept has been developed by DLR GSOC as TDP1 Mission Control Center. The concept is based on heritage programs TerraSAR-X and NFIRE and includes all necessary tasks and steps like calculation of feasible link slots based on satellite orbit and availability data, scheduling of customer link requests, and generation of operational products for the involved spacecrafts to execute the links. This paper gives an overview of the current Mission Control Center System Design of the TDP-1 program and its operational experiences

De novo methylation in male germ cells of the common marmoset monkey occurs during postnatal development and is maintained in vitro

The timing of de novo DNA methylation in male germ cells during human testicular development is yet unsolved. Apart from that, the stability of established imprinting patterns in vitro is controversially discussed. This study aimed at determining the timing of DNA de novo methylation and at assessing the stability of the methylation status in vitro. We employed the marmoset monkey (Callithrix jacchus) as it is considered the best non-human primate model for human testicular development. We selected neonatal, pre-pubertal, pubertal, and adult animals (n = 3, each) and assessed germ cell global DNA methylation levels by 5-methyl cytosine staining, and Alu elements and gene-specific methylation (H19, LIT1, SNRPN, MEST, OCT4, MAGE-A4, and DDX-4) by pyrosequencing. De novo methylation is progressively established during postnatal primate development and continues until adulthood, a process that is different in most other species. Importantly, once established, methylation patterns remained stable, as demonstrated using in vitro cultures. Thus, the marmoset monkey is a unique model for the study of postnatal DNA methylation mechanisms in germ cells and for the identification of epimutations and their causes

<i>De novo</i> methylation in male germ cells of the common marmoset monkey occurs during postnatal development and is maintained <i>in vitro</i>

<p>The timing of <i>de novo</i> DNA methylation in male germ cells during human testicular development is yet unsolved. Apart from that, the stability of established imprinting patterns <i>in vitro</i> is controversially discussed. This study aimed at determining the timing of DNA <i>de novo</i> methylation and at assessing the stability of the methylation status <i>in vitro</i>. We employed the marmoset monkey (<i>Callithrix jacchus</i>) as it is considered the best non-human primate model for human testicular development. We selected neonatal, pre-pubertal, pubertal, and adult animals (n = 3, each) and assessed germ cell global DNA methylation levels by 5-methyl cytosine staining, and <i>Alu</i> elements and gene-specific methylation (<i>H19, LIT1, SNRPN, MEST, OCT4, MAGE-A4</i>, and <i>DDX-4)</i> by pyrosequencing. <i>De novo</i> methylation is progressively established during postnatal primate development and continues until adulthood, a process that is different in most other species. Importantly, once established, methylation patterns remained stable, as demonstrated using <i>in vitro</i> cultures. Thus, the marmoset monkey is a unique model for the study of postnatal DNA methylation mechanisms in germ cells and for the identification of epimutations and their causes.</p

Supplement 1: Quantum-limited measurements of optical signals from a geostationary satellite

Supplementary Material Originally published in Optica on 20 June 2017 (optica-4-6-611