Las percepciones de crianza materna podrían influenciar las conductas autolesivas en adolescentes con diagnóstico de trastornos de la conducta alimentaria.

Objective: To explore the perceived parental rearing behavior in adolescents diagnosed with an eating disorder, and to identify eventual differences with altered eating and self-injurious behaviors. Material and methods: A total of 45 adolescents diagnosed with some eating disorder (11 diagnosed with anorexia nervosa, 23 with bulimia nervosa and 11 with binge eating disorder), recruited from the outpatient and hospitalization areas of the Juan N Navarro Children’s Psychiatric Hospital, were included. Results: It was found that the greater the memories of favoritism (r = 0.41, p-value = 0.005) or rejection (r = 0.36, p-value = 0.016) by the father, the higher the scores on the Eating Attitude Scale. Differences were also found in the mother’s warmth dimension, between the adolescents who presented self-injuries (mean = 39.6, de = 11.3) and those who did not present them (mean = 47.4, de = 8.8) (t =-2.6, value p = 0.015). Conclusions: Adolescents with a diagnosis of eating disorders presented differences in their perception of parental rearing, a factor that may decisively influence the manifestation of other psychopathological behaviors.Objetivo: Explorar las percepciones de crianza parental en adolescentes diagnosticados con algún trastorno de la conducta alimentaria, e identificar posibles diferencias con alteraciones de la conducta alimentaria y conductas autolesivas. Material y métodos: Un total de 45 adolescentes con algún tipo de trastorno de la conducta alimentaria (TCA) (11 diagnosticados con anorexia nervosa, 23 con bulimia nervosa y 11 con trastorno “por atracón”), pacientes en áreas de consulta externa y hospitalización del Hospital Psiquiátrico Infantil Juan N. Navarro fueron sistemáticamente estudiados. Resultados: Se encontró que cuánto mayores las percepciones de favoritismo (r =0,41, valor p = 0,005) o rechazo (r = 0,36, valor p = 0,016) del padre, mayores fueron también los puntajes en la Escala de Actitudes Alimentarias. Se encontraron asimismo diferencias en la dimensión de calidez de la madre, entre los adolescentes que presentaron autolesiones (media = 39,6, d.e = 11,3) comparados con aquéllos que no las presentaron (media = 47,4, d.e = 8.8) (t = -2,6, valor p = 0,015). Conclusiones: Los adolescentes con diagnóstico de TCA presentaron diferencias en la percepción de crianza parental, factor que puede influenciar decisivamente la manifestación de otras conductas psicopatológicas

Comportamiento del flujo sanguíneo cerebral en pacientes pediátricos quemados durante la fase ebb ingresados en una unidad de quemados

Introduction: the preservation of Cerebral Blood Flow (CBF) is very important to preserve the normal functions of the brain. The regulation of cerebral blood flow is mainly given by the contractile capacity of the blood vessels. Objective: to describe the behavior of cerebral blood flow during the ebb phase of burns in pediatric patients. Methods: a prospective, descriptive, prolective and cross-sectional study was carried out in pediatric patients with burns in the ebb phase who were included in an ultrasonographic neuromonitoring protocol. Results: the most affected age group was school children (n=25), and the most affected gender was male (n=37). The most common cause of burns was scald burns (n=42). A statistically significant association was found between age group and cause of burns (p<0.001). The pulstatility index was higher in male with 0.58 and school age with 0.61, the resistance index was equal between genders with 0.47 and higher in adolescents with 0.50, the Lingegaard index was higher in female with 1.31 and school age with 1.51. Conclusions: a correlation with a significant positive trend was found between the percentage of body surface area burned and the resistance index (p=0.031, rho=0.273).Introducción: la conservación del Flujo Sanguíneo Cerebral (FSC) es muy importante para preservar las funciones normales del encéfalo. La regulación de este, esta mediada principalmente por la capacidad contráctil de los vasos sanguíneos. Objetivo: describir el comportamiento del flujo sanguíneo cerebral en la fase ebb de las quemaduras en pacientes pediátricos. Material y métodos: se realizó un estudio prospectivo, descriptivo, prolectivo y transversal en pacientes pediátricos, con quemaduras en la fase ebb a los que se les incluyó en un protocolo ultrasonográfico de neuromonitorización. Resultados: el grupo etario más afectado fue el de escolares (n=25) por género el masculino (n=37). La causa de quemaduras más común fue por escaldadura (n=42). Se encontró una asociación estadísticamente significativa entre el grupo etario y la causa de quemaduras (p<0.001). El índice de pulsatilidad fue mayor en el género masculino con 0.58 y en edad escolar con 0.61, el índice de resistencia fue igual entre géneros con 0.47 y mayor en adolescentes con 0.50, el índice de Lingegaard fue mayor en el género femenino con 1.31 y en edad escolar con 1.51. Conclusiones: se encontró una correlación con tendencia positiva significativa entre el porcentaje de superficie corporal quemada y el índice de resistencia (p=0.031, rho=0.273)

Genes, the serotonergic system and suicidal behavior

The study of suicidal behavior has gained relevance given that recently about 50% of the population between 14 and 19 years old exhibit suicidal ideation and, in the population in general, there has been a rise of up to 150% in suicidal behavior. The outcomes of these studies of genetic epidemiology show that several genes may be associated with suicidal behavior. In particular, one of the hypotheses propounds that genes of proteins that participate in the serotonergic pathway could be responsible for the development of this behavior. There is neurochemical evidence showing alterations at different levels along this pathway. In this work, a review is made of several of the genes participating in the serotonergic pathway and their possible participation in suicidal behavior

Los Genes, el sistema serotoninergico y la conducta suicida

The study of suicidal behavior has gained relevance given that recently about 50% of the population between 14 and 19 years old exhibit suicidal ideation and, in the population in general, there has been a rise of up to 150% in suicidal behavior. The outcomes of these studies of genetic epidemiology show that several genes may be associated with suicidal behavior. In particular, one of the hypotheses propounds that genes of proteins that participate in the serotonergic pathway could be responsible for the development of this behavior. There is neurochemical evidence showing alterations at different levels along this pathway. In this work, a review is made of several of the genes participating in the serotonergic pathway and their possible participation in suicidal behavior.La conducta suicida es un problema de salud mental en el mundo. El estudio de la conducta suicida toma interés dado que en los años recientes, cerca del 50% de la población entre 14 y 19 años de edad presentan ideación suicida y en la población general se observa un aumento hasta del 150% en la conducta suicida. Estudios de epidemiología genética muestran que los genes pueden estar asociados a la conducta suicida. Recientemente se ha propuesto que los genes involucrados en la llamada vía serotoninérgica están participando, ya que evidencia neuroquímica demuestran alteraciones a diferentes niveles. Sin embargo, en población latina son pocos los estudios que evalúen el papel de los genes para generar estas condiciones. En este trabajo, se presenta una revisión de los principales genes que participan en la vía serotoninérgica y presenta evidencia de la participación de esos en la conducta suicida

Los Genes, el sistema serotoninergico y la conducta suicida

The study of suicidal behavior has gained relevance given that recently about 50% of the population between 14 and 19 years old exhibit suicidal ideation and, in the population in general, there has been a rise of up to 150% in suicidal behavior. The outcomes of these studies of genetic epidemiology show that several genes may be associated with suicidal behavior. In particular, one of the hypotheses propounds that genes of proteins that participate in the serotonergic pathway could be responsible for the development of this behavior. There is neurochemical evidence showing alterations at different levels along this pathway. In this work, a review is made of several of the genes participating in the serotonergic pathway and their possible participation in suicidal behavior.La conducta suicida es un problema de salud mental en el mundo. El estudio de la conducta suicida toma interés dado que en los años recientes, cerca del 50% de la población entre 14 y 19 años de edad presentan ideación suicida y en la población general se observa un aumento hasta del 150% en la conducta suicida. Estudios de epidemiología genética muestran que los genes pueden estar asociados a la conducta suicida. Recientemente se ha propuesto que los genes involucrados en la llamada vía serotoninérgica están participando, ya que evidencia neuroquímica demuestran alteraciones a diferentes niveles. Sin embargo, en población latina son pocos los estudios que evalúen el papel de los genes para generar estas condiciones. En este trabajo, se presenta una revisión de los principales genes que participan en la vía serotoninérgica y presenta evidencia de la participación de esos en la conducta suicid

Association between SARS-CoV-2 Infection and Neuropsychiatric Manifestations

Coronaviruses are neurotropic viruses capable of entering the brain through various mechanisms and generating an important inflammatory response that is capable of triggering neuropsychiatric manifestations. Several reports describe the appearance of different conditions, such as sleep problems, anxiety and depression disorders, acute psychotic disorders, encephalitis, and delirium, among others, associated with COVID-19 infection. We performed a literature review in PubMed, Springer, Nature, MDPI, and other scientific journals on the relationship between COVID-19 infection with the development and aggravation of neuropsychiatric manifestations explained by molecular changes secondary to SARS-CoV-2 where it was found that there is a relationship between the virus and the development of these manifestations. Prospective neuropsychiatric follow-up of people exposed to SARS-CoV-2 at different points in their lives, as well as their neuroimmunological status, is necessary to fully understand the long-term impact of COVID-19 on mental health. It is required to identify the risk of developing neuropsychiatric problems due to COVID-19 infection to provide better medical care from a multidisciplinary team and improve the prognosis of these patients as well as the treatment of long-term sequelae