7 research outputs found

    Nonlinearity parameter B/A of biological tissue ultrasound imaging in echo mode

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    International audienceThe nonlinearity B/A parameter influences the distortion of ultrasound waves during their propagation in tissue. Normal and pathological media have different B/A values and this parameter may be used to characterize them. In this paper the multitaper coherent plane wave compounding (MCPWC) is combined with the extended comparative method (ECM) to estimate the B/A parameter in simulation and acquisition. Using plane wave transmission and orthogonal apodization during beam forming improves the B/A estimation and delineation

    Critical behavior and magnetic entropy change in Nd0.7Sr0.1Ba0.1Ca0.1MnO3−δ perovskite manganite

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    The aim of our study was to investigate the critical exponents of Nd0.7Sr0.1Ba0.1Ca0.1MnO3−δ material around its paramagnetic to ferromagnetic phase transition. Reliable critical exponents i.e. β=0.355, γ=1.329, and δ=4.867 at the critical temperature TC=117 K were refined using modified Arrott plot and Kouvel–Fisher methods. The critical exponent δ=4.760±0.129 was further separately determined from the isothermal magnetization data. Finally these critical exponents fulfill the Widom scaling relation δ=1+γ/β. Based on these analysis, the magnetization–field–temperature (M–H–T) data around TC collapses into two independent curves obeying the single scaling equation M(H,ε)=|ε|βf±(H/|ε|β+γ), with ε=(T−TC)/TC is the reduced temperature. Once again, the critical exponents are confirmed by the field dependence of the magnetic entropy change relation ∆SM|T=TC ∞Hn with n=1+(β−1)/(β+1). The obtained critical exponents for Nd0.7Sr0.1Ba0.1Ca0.1MnO3−δ manganite are in accordance with the prediction of the 3D-Heisenberg model with short-range magnetic interactions. The temperature dependence of specific heat and magnetic entropy change ΔSM further supports second order PM–FM phase transition and shed light the A-site-disordered perovskite effect on the magnetocaloric properties

    GENESIS: a French national resource to study the missing heritability of breast cancer

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    International audienceBackground: Less than 20 % of familial breast cancer patients who undergo genetic testing for BRCA1 and BRCA2 carry a pathogenic mutation in one of these two genes. The GENESIS (GENE SISter) study was designed to identify new breast cancer susceptibility genes in women attending cancer genetics clinics and with no BRCA1/2 mutation. Methods: The study involved the French national network of family cancer clinics. It was based on enrichment in genetic factors of the recruited population through case selection relying on familial criteria, but also on the consideration of environmental factors and endophenotypes like mammary density or tumor characteristics to assess potential genetic heterogeneity. One of the initial aims of GENESIS was to recruit affected sibpairs. Siblings were eligible when index cases and at least one affected sister were diagnosed with infiltrating mammary or ductal adenocarcinoma, with no BRCA1/2 mutation. In addition, unrelated controls and unaffected sisters were recruited. The enrolment of patients, their relatives and their controls, the collection of the clinical, epidemiological, familial and biological data were centralized by a coordinating center
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