91 research outputs found

    Processo de fabricação de HBT em camadas de InGaP/GaAs

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    Orientador : Jacobus Willibrordus SwartTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Eletrica e de ComputaçãoDoutorad

    Consecutive assessment of FA and ADC values of normal lumbar nerve roots from the junction of the dura mater

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    Background: Diffusion weighted imaging (DWI) and diffusion tensor imaging (DTI) are widely used in the evaluation of the central nervous system and recently have been reported as a potential tool for diagnosis of the peripheral nerve or the lumbar nerve entrapment. The purpose of this study was to evaluate consecutive changes in apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values of normal lumbar nerve roots from the junction of the dura mater. Methods: The lumbar spinal nerves were examined in 6 male healthy volunteers (mean age, 35 years) with no experiences of sciatica, with a 3.0-T MR unit using a five-element phased-array surface coil. DTI was performed with the following imaging parameters: 11084.6/73.7 ms for TR/TE; b-value, 800 s/mm2; MPG, 33 directions; slice thickness, 1.5 mm; and total scan time, 7 min 35 s. ADC and FA values at all consecutive points along the L4, L5 and S1 nerves were quantified on every 1.5 mm slice from the junction of the dura mater using short fiber tracking. Results: ADC values of all L4, 5, and S1 nerve roots decreased linearly up to 15 mm from the dura junction and was constant distally afterward. ADC values in the proximal portion demonstrated S1 > L5 > L4 (p L5 > S1 (p < 0.05). Conclusion: Our study demonstrated that ADC and FA values of each L4, 5, and S1 at the proximal portion from the junction of the dura matter changed linearly. It would be useful to know the normal profile of DTI values by location of each nerve root so that we can detect subtle abnormalities in each nerve root

    A bimodal catalytic membrane having a hydrogen-permselective silica layer on a bimodal catalytic support: Preparation and application to the steam reforming of methane

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    The steam reforming of methane for hydrogen production was experimentally investigated using catalytic membrane reactors, consisting of a microporous silica top layer, for the selective permeation of hydrogen, and an α-alumina support layer, for catalytic reaction of the steam reforming of methane. An α-alumina support layer with a bimodal structure, which was proposed for the enhanced dispersion of Ni catalysts, was prepared by impregnating γ-Al2O3 inside α-Al2O3 microfiltration membranes (1 μm in pore diameter), and then immersing the membranes in a nickel nitrate solution, resulting in a bimodal catalytic support. The bimodal catalytic support showed a large conversion of methane at a high space velocity compared with a conventional catalytic membrane with a monomodal structure. The enhanced activity of Ni-catalysts in bimodal catalytic supports was confirmed by hydrogen adsorption measurements. A bimodal catalytic membrane, i. e., a silica membrane coated on a bimodal catalytic support, showing an approximate selectivity of hydrogen over nitrogen of 100 with a hydrogen permeance of 0.5-1x10-5 m3 m-2 s-1 kPa-1 was examined for the steam reforming of methane. The reaction was carried out at 500 °C, and the feed and permeate pressures were maintained at 100 and 20 kPa, respectively. Methane conversion could be increased up to approximately 0.7 beyond the equilibrium conversion of 0.44 by extracting hydrogen from the reaction stream to the permeate stream

    A photocatalytic membrane reactor for VOC decomposition using Pt-modified titanium oxide porous membranes

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    Porous titanium oxide membranes with pore sizes in the range of 2.5-22 nm were prepared by a sol-gel procedure, and were applied for decomposition of methanol and ethanol as model volatile organic compounds (VOCs) in a photocatalytic membrane reactor, where oxidation reaction occurs both on the surface and inside the porous TiO2 membrane while reactants are permeating via one-pass flow. Methanol was completely photo-oxidized by black-light irradiation to CO2 when methanol at a concentration of 100 ppm was used at a feed flow rate of 500 × 10-6 m3/min, but the conversion decreased when the MeOH concentration in the feed was increased. Pt-modification was carried out by photo-deposition, and led to a decrease in pore diameter. Using Pt-modified membranes, a nearly complete oxidation of methanol up to 10,000 ppm at a feed flow rate of 500 × 10-6 m3/min was observed. Thus, such membranes would be effective for purifying a permeate stream after one-pass permeation through the TiO2 membranes. The decomposition of ethanol is also discussed

    Diffusion-Weighted Imaging and Diffusion Tensor Imaging of Asymptomatic Lumbar Disc Herniation

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    Diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) were performed on a healthy 31-year-old man with asymptomatic lumbar disc herniation. Although the left S1 nerve root was obviously entrapped by a herniated mass, neither DWI nor DTI showed any significant findings for the nerve root. Decreased apparent diffusion coefficient (ADC) values and increased fractional anisotropy (FA) values were found. These results are contrary to those in previously published studies of symptomatic patients, in which a combination of increased ADC and decreased FA seem to have a relationship with nerve injury and subsequent symptoms, such as leg pain or palsy. Our results seen in an asymptomatic subject suggest that the compressed nerve with no injury, such as edema, demyelination, or persistent axonal injury, may be indicated by a combination of decreased ADC and increased FA. ADC and FA could therefore be potential tools to elucidate the pathomechanism of radiculopathy

    Osseous erosion by herniated nucleus pulposus mimicking intraspinal tumor: a case report

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    Erosion of spinal osseous structure, so-called scalloping, has been rarely reported associated with herniated nucleus pulposus (HNP). We report a rare case of HNP causing erosion of the spinal osseous structure (including lamina). The patient was an 81-year-old woman with 3-year history of low-back pain and left leg radiating pain. Muscle weakness of the left leg was also apparent. Computed tomography following myelography showed severe compression of the dural sac at the level of L3–L4; furthermore, erosion of the lamina, pedicle, and vertebral body was noted, indicating that the space-occupying mass was most probably a tumorous lesion. The mass also showed calcification inside. During the surgery, the mass was confirmed to be an HNP with calcification. Following resection, the pain disappeared. Surgeons should be aware of the possibility of scalloping of the vertebrae caused by HNP mimicking a tumorous lesion

    Indication and benefit of upfront hematopoietic stem cell transplantation for T-cell lymphoblastic lymphoma in the era of ALL-type induction therapies

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    Since the introduction of leukemia-type induction therapies for T-cell lymphoblastic lymphoma (T-LBL), improvements in the long-term outcomes of T-LBL have been reported. However, indications for and the appropriate timing of hematopoietic stem cell transplantation (HSCT) have not yet been established. Therefore, we performed a multicenter retrospective cohort study of patients with T-LBL treated using leukemia-type initial therapies to compare the outcomes after HSCT at different disease stages. We enrolled 21 patients with T-LBL from a total of 11 centers, and all patients received hyper-CVAD as a leukemia-type initial regimen. HSCT was performed during the CR1/PR1 (standard disease) stage in 11 patients, while it was completed at a later or non-remission (advanced disease) stage in 10 patients. Following HSCT, the overall survival rate was significantly greater in standard disease than in advanced-disease patients (79.5% vs. 30.0% at 5 years; hazard ratio (HR) 5.97; p = 0.03), with trend to the lower incidence of relapse in the former group (27.3% vs. 60.0% at 5 years; HR 2.29; p = 0.19). A prognostic difference was not detected between cases treated with allogeneic and autologous HSCTs. Our study suggests that frontline HSCT may be a feasible treatment option for T-LBL, even in the era of leukemia-type initial therapy
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