プロダクト プランニング ニ オケル デフレーム ロジック ノ センリャクテキ ソクメン

多様化した消費者ニーズに呼応してプロダクトの差異化が進展している。しかし、競合プロダクトの台頭に伴いコモディティ化が進んで同質的になり、差異化による比較優位性の訴求が難しくなる。このため、顧客価値の送達がプロダクト・プランニングにおいて課題として検討されており、QFDの手法を織り込んだデフレームのコンセプトをベースとしている。分析の結果、代替品の性能向上で市場が縮小する場合でも、デジタルカメラ市場では差異化戦略が有効で、プロダクトの特性が訴求できるカテゴリーの形成や上方へのカテゴリー・シフトが起きている事態が明らかになった。Products have been differentiated according to consumer needs. However, it has been difficult to appeal to comparative advantage by differentiation, caused by being homogenous through the development of commoditization with the rise of competitive products. For this reason, reviewing the delivery of customer value in product planning as a task in progress is based on the concept of de-frame, incorporating the technique of QFD. As a result of this analysis, differentiation strategy is effective in the case of a shrinking market accompanied by the improvement of substitutes such as in the digital camera market. In addition, it became obvious that the matter of the formation of category and category-shift upward can make a product feature more appealing

ターゲット マーケティング ノ カテゴライズド アドレサビリティ ノ カクダイ

マーケティング戦略の基底をなすターゲット・マーケティングのスタイルは、組織のミッションやドメイン、競争環境に応じて変わる。製品・サービスの差異に着目し、差異に呼応、適応した戦略的行動が競争優位につながることは現代マーケティングの前提である。新規技術の導入や競争環境の激化を反映したターゲット・マーケティングの新たな局面は製品の主要なベネフィットに基づくプラットフォーム・セグメンテーションであり、日用品などのケースに代表されるように、包括的なターゲット・マーケティングをカテゴライズ(類別)することで抽出されるアドレサビリティ(対処力、対応能力)の広がりを論じていく。Styles of target marketing used as basis of marketing strategies are different depending on mission of organization, domain, and competitive environment. Strategic behaviors which pay attention to differences and adapt to differences lead to competitive advantages is premises on modern marketing. The new phases of target marketing which introduce new technology and reflect cut-throat competition is platform segmentation which based on primary benefit, and discuss the expansion of addressability extracted by categorization of the comprehensive target marketing, represented by the cases of daily care goods and so on

ツーリズム マーケティング ニ オケル サイカ セイサク ノ フクゴウ コウゾウ

ツーリズム・マーケティングは、ツーリズムの活性化のためにマーケティングのコンセプトや政策、戦略を援用するものである。ツーリズムの目的地は、地域の歴史的背景、自然環境等に依拠する個性を保持しており、個性をツーリスティック・リソーシズとして活用している。他方で、わが国ではリスク分散を企図して、差異化とは反対に、総合的な施設の配置や総合的なパッケージを通じたツーリズムの標準化、画一化が進行してきた。パッケージ・ツアー、デスティネーションにブランドを付与して、ニュー・ツーリズムを導入しながら業容拡大を図るツーリズム産業の差異化政策の構造の複合性に着目する。そのうえで、ツーリズム産業の現在の課題と克服を通じた活性化のための差異化の態様を論じていく。Tourism marketing intends to invoke the concepts, policies and strategies of marketing, for the activation of tourism. Subject of tourism holds the individualities relying on the historical background of the region, natural environment, and etc. And we are utilizing the individualities as touristic resources. On the other hand, in our country, for diversification of risk, the standardization and the uniformity have progressing, in opposition to the differentiation through the allocation of all-round touristic institutions and comprehensive package tour. We focus on the complex structure of the differentiation policy in the tourism industry introducing the new tourism in order to expand the business, branding the package tour and destination. And we discuss the differentiation mode for the activation through the problems and its solutions at present in the tourism industry

ターゲット マーケティング ニ オケル コキャク イジ センリャク ノ カイソウセイ

防衛戦略は、競争回避の消極的戦略とみなされてきた。しかし、防衛戦略は顧客維持戦略とほぼ同義であり、顧客を明確化するターゲット・マーケティングにおいては、大きな意義を有している。そこで、防衛戦略の基本的な定式を整理し、顧客維持戦略とリレーションシップ・マーケティングの戦略的枠組みを分析する。企業成長に不可欠な防衛戦略、顧客維持戦略は、顧客満足やロイヤルティを生みだすCRM(Customer Relationship Management)のコンセプトを通じて、顧客のカテゴリー化、差異的待遇によって補強される。almost synonym of customer retention strategy and has great significance in target marketing which identifies customers. So, I put together existing basic formulas of defensive strategy and analyze the customer retention strategy and the strategic framework of relationship marketing. Defensive strategy and customer retention strategy which are both indispensable to the growth of the corporation are reinforced by categorization of customer and differential treatment through the concept of CRM(Customer Relationship Management)which creates customer satisfaction and loyalty

A Longitudinal SPECT Study of Different Patterns of Regional Cerebral Blood Flow in Alzheimer's Disease with or without Diabetes

Aims: To determine the effect of diabetes mellitus (DM) on regional cerebral blood flow (rCBF) patterns in patients with Alzheimer’s disease (AD). Methods: We investigated the initial rCBF of 71 AD patients (36 without DM and 35 with DM) and the final rCBF of 23 AD patients (12 without DM and 11 with DM) after an average of 32 months. Single-photon emission computed tomography (SPECT) data were analyzed by statistical brain imaging. Results: The initial SPECT showed that AD patients without DM had lower rCBF in the left and right inferior temporal gyri than AD patients with DM. A follow-up SPECT demonstrated that rCBF decreased in more widespread regions, including the parietal, temporal, frontal, and limbic lobes, in AD patients without than with DM. Conclusion: This study suggests that functional brain abnormalities in AD differ depending on the DM status at baseline and during follow-up, reflecting neuropathologic differences

Irinotecan Hydrochloride (CPT-11) in Dialysis Patients with Gastrointestinal Cancer

We investigated changes in drug disposition and toxicities with CPT-11 in 15 dialysis patients with gastrointestinal cancers to clarify whether CPT-11 could be administered safely in such patients. For comparison, the same parameters were also investigated in 10 cancer patients not undergoing dialysis. Items investigated included (1) plasma concentrations of SN-38, SN-38G and CPT-11 at 0, 1, 12, 24, 36, 48 and 72h after administration, together with a comparison of mean AUC values for 3 dose levels of CPT-11 (50, 60 and 70mg/m2) in dialysis patients and controls;and (2) occurrence of adverse events. Several findings emerged from this study:(1) No significant difference was observed in the AUC for SN-38 or CPT-11 between the dialysis and control groups;(2) The AUC for SN-38G at each dose was significantly higher in dialysis patients;and (3) Grade 1-4 leucopenia was observed in 11 of the dialysis patients. One patient developed grade 4 leucopenia and died due to sepsis. Anorexia, diarrhea, nausea, alopecia and interstitial pneumonia occurred in 6 dialysis patients. We found changes in drug dispositions of CPT-11, SN-38 and SN-38G in dialysis patients, suggesting that hepatic excretion, especially that of SN-38G, was increased. No significant difference in occurrence of adverse events was observed between the 2 groups. This indicates that CPT-11 can be administered safely in patients on dialysis.</p

Intimal sarcoma from the iliac artery

We present a rare case of intimal sarcoma arising from the common iliac artery in an 82-year-old man who presented with intermittent claudication. He had undergone endovascular therapy with self-expanding stents to both iliac arteries that had occluded soon after placement. After salvage bypass grafting, a diagnosis of intimal sarcoma with angiosarcoma phenotype from the iliac artery was made. Further bypass graft surgery relieved symptoms temporarily. However, the tumor progressed and the left limb became ischemic. The chemotherapy of eribulin did not prevent tumor progression. The patient died of the disease 20 months after the first surgery