2,605 research outputs found

    Professional learning for school principals: development in Scotland

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    This paper discusses the recent origins and development of professional learning and especially preparation programmes for Scottish school principals. Scotland has adopted a 'standards' based approach to continuing professional development and a Framework if Standards has emerged since 1998. A synthesis of the official reports and some of the research available is offered with a view to highlighting the further developments now being advocated and consulted upon under the aegis if a teacher-focused national Continuous Professional Development Advisory Group and its sub-group on leadership

    Domain discovery method for topological profile searches in protein structures

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    We describe a method for automated domain discovery for topological profile searches in protein structures. The method is used in a system TOPStructure for fast prediction of CATH classification for protein structures (given as PDB files). It is important for profile searches in multi-domain proteins, for which the profile method by itself tends to perform poorly. We also present an O(C(n)k +nk2) time algorithm for this problem, compared to the O(C(n)k +(nk)2) time used by a trivial algorithm (where n is the length of the structure, k is the number of profiles and C(n) is the time needed to check for a presence of a given motif in a structure of length n). This method has been developed and is currently used for TOPS representations of protein structures and prediction of CATH classification, but may be applied to other graph-based representations of protein or RNA structures and/or other prediction problems. A protein structure prediction system incorporating the domain discovery method is available at http://bioinf.mii.lu.lv/tops/

    The influence of hydrilla infestation and drawdown on the food habits and growth of age-0 largemouth bass in the Atchafalaya River Basin, Louisiana

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    I compared diets and growth rates of age-0 largemouth bass in the Atchafalaya River Basin (Basin), Louisiana, to determine how hydrilla Hydrilla verticillata densities and drawdown influence bass food habits and growth. To assess hydrilla density effects on diet, I compared food habits of age-0 bass collected in high, intermediate, and low hydrilla densities, as well as in Henderson Lake, a semi-isolated portion of the Basin subject to drawdowns in 2001 and 2002 to reduce hydrilla densities. I also compared diets of age-0 bass from sites sampled in 2001 and 2002 that were also sampled in the mid-1970s before hydrilla had colonized the Basin. Frequency of occurrence and percentage of the diet by weight composed of fish prey consistently decreased as hydrilla coverage increased. Bass switched to a more fish-dominated diet sooner in Lake Henderson after the 2001 drawdown, but the importance of fishes in the diet decreased quickly as hydrilla beds became re-established. Effects of the 2002 drawdown in Lake Henderson lasted much longer, and age-0 bass switched to a piscivorous diet sooner and maintained a more fish-dominated diet throughout the spring and summer relative to bass collected from hydrilla-infested areas of the Basin. Length frequencies and mean length in August revealed smaller bass in areas affected by high hydrilla densities, however, there was no evidence that drawdown resulted in a growth advantage for age-0 largemouth bass. Mean length and weight of age-0 largemouth bass was significantly lower in areas supporting high hydrilla densities compared to habitats with intermediate and low hydrilla abundance. Results indicate high hydrilla coverage has major effects on the diet of age-0 largemouth bass, and those effects are reflected in reduced growth of individuals inhabiting high-density hydrilla beds

    The Thermal Degradation of Copolymers of Methyl Methacrylate and Methyl Acrylate and Some Related Topics

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    Abstract Not Provided

    Theory of Magnetic Short--Range Order for High-T_c Superconductors

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    A theory of magnetic short--range order for high--TcT_c cuprates is presented on the basis of the one--band tt--tt^{\prime}--Hubbard model combining the four--field slave--boson functional integral technique with the Bethe cluster method. The ground--state phase diagram evaluated self--consistently at the saddle--point and pair--approximation levels shows the experimentally observed suppression of magnetic long--range order in the favour of a paraphase with antiferromagnetic short--range order. In this phase the uniform static spin susceptibility consists of interrelated itinerant and local parts and increases upon doping up to the transition to the Pauli paraphase. Using realistic values of the Hubbard interaction we obtain the cusp position and the doping dependence of the zero--temperature susceptibility in reasonable agreement with experiments on La2δSrδCuO4\rm La_{2-\delta}Sr_{\delta}CuO_4.Comment: 3 pages, 2 Postscript figure, Proc. Int. Conf. SCES Zuerich Switzerland Aug. 96, to appear in Physica

    Elastic-Tether Suits for Artificial Gravity and Exercise

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    Body suits harnessed to systems of elastic tethers have been proposed as means of approximating the effects of normal Earth gravitation on crewmembers of spacecraft in flight to help preserve the crewmembers physical fitness. The suits could also be used on Earth to increase effective gravitational loads for purposes of athletic training. The suit according to the proposal would include numerous small tether-attachment fixtures distributed over its outer surface so as to distribute the artificial gravitational force as nearly evenly as possible over the wearer s body. Elastic tethers would be connected between these fixtures and a single attachment fixture on a main elastic tether that would be anchored to a fixture on or under a floor. This fixture might include multiple pulleys to make the effective length of the main tether great enough that normal motions of the wearer cause no more than acceptably small variations in the total artificial gravitational force. Among the problems in designing the suit would be equalizing the load in the shoulder area and keeping tethers out of the way below the knees to prevent tripping. The solution would likely include running tethers through rings on the sides. Body suits with a weight or water ballast system are also proposed for very slight spinning space-station scenarios, in which cases the proposed body suits will easily be able to provide the equivalency of a 1-G or even greater load

    Jet heat transfer in the vicinity of a rotating grinding wheel

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    Abstract: Impinging jets are known as a method of achieving high convective heat transfer coefficients. One potential application of impinging jet heat transfer is the air jet cooling of a grinding process. A grinding process generates heat that must be dissipated to avoid thermal damage. To date, this has been achieved using flood cooling with a traditional coolant such as an oil and water mixture; however, using a jet of air in its place has obvious environmental and economic benefits. For a range of grinding test configurations, results are presented of the convective heat transfer from the workpiece, along the notional plane of cut, and of the air flow velocity in a two-dimensional plane perpendicular to the workpiece. It has been shown that a boundary layer that develops around the rotating grinding wheel has the effect of displacing a peak in the distribution of the local heat transfer coefficient from the notional arc of cut. To effectively cool the grinding zone, therefore, it is necessary to penetrate this boundary layer and this can only be achieved when the jet velocity is substantially greater than the tangential velocity of the wheel

    ArrayWiki: an enabling technology for sharing public microarray data repositories and meta-analyses

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    © 2008 Stokes et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.DOI: 10.1186/1471-2105-9-S6-S18Background. A survey of microarray databases reveals that most of the repository contents and data models are heterogeneous (i.e., data obtained from different chip manufacturers), and that the repositories provide only basic biological keywords linking to PubMed. As a result, it is difficult to find datasets using research context or analysis parameters information beyond a few keywords. For example, to reduce the "curse-of-dimension" problem in microarray analysis, the number of samples is often increased by merging array data from different datasets. Knowing chip data parameters such as pre-processing steps (e.g., normalization, artefact removal, etc), and knowing any previous biological validation of the dataset is essential due to the heterogeneity of the data. However, most of the microarray repositories do not have meta-data information in the first place, and do not have a a mechanism to add or insert this information. Thus, there is a critical need to create "intelligent" microarray repositories that (1) enable update of meta-data with the raw array data, and (2) provide standardized archiving protocols to minimize bias from the raw data sources. Results. To address the problems discussed, we have developed a community maintained system called ArrayWiki that unites disparate meta-data of microarray meta-experiments from multiple primary sources with four key features. First, ArrayWiki provides a user-friendly knowledge management interface in addition to a programmable interface using standards developed by Wikipedia. Second, ArrayWiki includes automated quality control processes (caCORRECT) and novel visualization methods (BioPNG, Gel Plots), which provide extra information about data quality unavailable in other microarray repositories. Third, it provides a user-curation capability through the familiar Wiki interface. Fourth, ArrayWiki provides users with simple text-based searches across all experiment meta-data, and exposes data to search engine crawlers (Semantic Agents) such as Google to further enhance data discovery. Conclusions. Microarray data and meta information in ArrayWiki are distributed and visualized using a novel and compact data storage format, BioPNG. Also, they are open to the research community for curation, modification, and contribution. By making a small investment of time to learn the syntax and structure common to all sites running MediaWiki software, domain scientists and practioners can all contribute to make better use of microarray technologies in research and medical practices. ArrayWiki is available at http://www.bio-miblab.org/arraywiki

    Assessing with e-Ase

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    The Educational Development Unit have produced a guide to assist academic staff in transforming assessment practices underpinned by technology. 'Assessing with e-Ase' highlights how technology combined with sound pedagogy has the potential to enhance the student experience of learning, teaching and assessment. Drawing on the experiences, knowledge and understanding of the e-assessment project at Middlesex University, it offers a consideration of contextual, procedural and logistical factors that may impact when using e-assessment practices. Key issues for consideration when developing and implementing e-assessment are included along with the part played by policy and strategy. Examples of departmental case studies, an outline of the support available to staff and links to resources that may provide useful additional information are also included

    Formality and informality in the summative assessment of motor vehicle apprentices: a case study

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    This article explores the interaction of formal and informal attributes of competence‐based assessment. Specifically, it presents evidence from a small qualitative case study of summative assessment practices for competence‐based qualifications within apprenticeships in the motor industry in England. The data are analysed through applying an adaptation of a framework for exploring the interplay of formality and informality in learning. This analysis reveals informal mentoring as a significant element which influences not only the process of assessment, but also its outcomes. We offer different possible interpretations of the data and their analysis, and conclude that, whichever interpretation is adopted, there appears to be a need for greater capacity‐building for assessors at a local level. This could acknowledge a more holistic role for assessors; recognise the importance of assessors’ informal practices in the formal retention and achievement of apprentices; and enhance awareness of inequalities that may be reinforced by both informal and formal attributes of assessment practices
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