22 research outputs found
Single Center and Surgeon's Long-Term (15-19 Years) Patient Satisfaction and Revision Rate of Round Textured Eurosilicone Breast Implants
BACKGROUND: Breast augmentation is one of the most commonly performed aesthetic plastic surgical procedures, with over 250 thousand procedures in the United States in 2020 alone. However, the safety of breast implants should be closely researched and monitored, especially on the long-term. OBJECTIVES: This study was undertaken to evaluate the long-term results of round micro-textured Eurosilicone (Eurosilicone S.A.S, Apt Cedex, France) Cristalline Paragel breast implants from a single centre, single surgeon experience, regarding both patient-reported outcome measures as well as revisions. METHODS: A retrospective cohort study was undertaken of 84 patients who underwent primary breast augmentation with round micro-textured Eurosilicone Cristalline Paragel breast implants, either submuscular (dual-plane) or subglandular placed, in the period between 2001 and 2004. All patients were contacted for informed consent and after approval, the validated BREAST-Q questionnaire was sent and used to analyze patient satisfaction. In addition, objective data regarding revisions, including capsular contracture, rupture rate, pain and/or aesthetic causes needing revision surgery, were analyzed. RESULTS: High BREAST-Q scores (67-100% for 0-100 scale variables and 66.0-77.3% of the patients scored "very satisfied" on categorical variables) were found without clinically significant differences between patients with dual-plane placed implants and subglandular placed implants. The overall revision rate was 29.8%, also with no significant differences between both groups (p=0.317). CONCLUSIONS: This study showed high patient satisfaction and relatively low revision rates after 15-19 years follow-up of round micro-textured Eurosilicone Cristalline Paragel breast implants. No clinically relevant significant differences were found between dual-plane and subglandular placement of the implants
Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors
Peer reviewedPublisher PD
Nine Human Epidemiological Studies on Synthetic Amorphous Silica and Respiratory Health
The respiratory health effects of Synthetic Amorphous Silica (SAS) have been studied in human epidemiological research. This article presents a historical overview and review of nine occupational worker studies that have been conducted so far on this topic. The combined study population of all of these studies included 1,172 employees, and exposure concentrations ranged from <1mg/m to 100mg/m . In two studies with a total of 293 workers, the incidence of silicosis was investigated after long-term exposure to precipitated SAS, and no cases of silicosis were found (Plunkett and Dewitt, 1962; Volk, 1960). In another study, the spirometry results of 40 workers were normal (Vitums et al., 1977). In a study of 28 workers, 4 cases of silicosis were identified, but it is possible that contamination with cristobalite occurred and detailed information about the amorphous silica origin was not provided (Mohrmann and Kahn, 1985). Ferch et al. (1987) found that lung impairment was associated with confounding factors (smoking) but not with exposure to precipitated SAS in a study of 143 workers. Choudat et al. (1990) reported a reduction in forced expiratory flow in a group exposed to precipitated SAS compared to a control group. Still, they found no correlation between the extent of exposure and pulmonary function was found in a study of 131 workers. Wilson et al. (1979) also failed to show a significant association between the degree of exposure to precipitated SAS and annual changes in lung function in a study of 165 workers. In the most recent and most extensive study (Taeger et al., 2016; Yong et al., 2022) in Germany, involving 462 factory workers, no association between inhalable or respirable SAS dust exposure and respiratory health was reported. Based on the available data, there is no evidence-base to support a relationship between SAS and respiratory health in humans
Correction: Psychological Distress in the Hospital Setting: A Comparison between Native Dutch and Immigrant Patients.
[This corrects the article DOI: 10.1371/journal.pone.0130961.]
Correction: Psychological Distress in the Hospital Setting: A Comparison between Native Dutch and Immigrant Patients
Ethnic Minorities with Diabetes Differ in Depressive and Anxiety Symptoms and Diabetes-Distress
Objective. To determine the association between ethnicity, diabetes-distress, and depressive and anxiety symptoms in adult outpatients with diabetes. Research Design and Methods. Diabetes-distress (Problem Areas in Diabetes Scale, PAID5), depressive and anxiety symptoms (Extended Kessler-10, EK10), and quality of life (Short-Form 12, SF12) were assessed in an ethnic diverse diabetes outpatient population of a teaching hospital in Amsterdam. Descent of one's parents and self-classified ethnicity were obtained to define ethnicity. HbA1c, clinical data, and socioeconomic status were derived from the medical charts. Based on established cut-offs for PAID5- and EK10-scores, emotional distress was dichotomized for the purpose of logistic regression analyses. Results. Of 1007 consecutive patients approached, 575 participated. Forty-nine percent were of non-Dutch ethnicity and 24.7% had type 1 diabetes. Diabetes-distress was reported by 12.5% of the native Dutch patients and by 22.0%, 34.5%, and 42.6% of the Surinamese, Turkish, and Moroccan patients, respectively. Prevalence of depressive symptoms was 9.4% in native Dutch patients and 20.4%, 34.5%, and 27.3% in the other groups mentioned. Diabetes-distress and Moroccan origin were significantly associated (OR = 3.60, p<.01) as well as depressive symptoms and Turkish origin (OR = 4.23, p=.04). Conclusions. Different ethnic minorities with diabetes vary in their vulnerability for emotional distress, warranting clinical attention. Future research should elucidate explanatory factors and opportunities for tailored interventions
Outcomes of primary versus conversional Roux-En-Y gastric bypass after laparoscopic sleeve gastrectomy: a retrospective propensity score–matched cohort study
Abstract Background Conversional surgery is common after laparoscopic sleeve gastrectomy (LSG) because of suboptimal weight loss (SWL) or poor responders and gastroesophageal reflux disease (GERD). Roux-en-Y gastric bypass (RYGB) is the most common conversional procedure after LSG. Methods A retrospective cohort study analyzed patients who underwent primary RYGB (PRYGB) or conversional RYGB (CRYGB) at three specialized bariatric centers between 2008 and 2019 and tested for weight loss, resolution of GERD, food tolerance (FT), early and late complications, and the resolution of associated medical problems. This was analyzed by propensity score matching (PSM). Results In total, 558 (PRYGB) and 155 (CRYGB) completed at least 2 years of follow-up. After PSM, both cohorts significantly decreased BMI from baseline (p < 0.001). The CRYGB group had an initially more significant mean BMI decrease of 6.095 kg/m2 at 6 months of follow-up (p < 0.001), while the PRYGB group had a more significant mean BMI decrease of 5.890 kg/m2 and 8.626 kg/m2 at 1 and 2 years, respectively (p < 0.001). Food tolerance (FT) improved significantly in the CRYGB group (p < 0.001), while CRYGB had better FT than PRYGB at 2 years (p < 0.001). A GERD resolution rate of 92.6% was recorded in the CRYGB (p < 0.001). Both cohorts had comparable rates of early complications (p = 0.584), late complications (p = 0.495), and reoperations (p = 0.398). Associated medical problems at 2 years significantly improved in both cohorts (p < 0.001). Conclusions CRYGB is a safe and efficient option in non- or poor responders after LSG, with significant weight loss and improvement in GERD. Moreover, PRYGB and CRYGB had comparable complications, reoperations, and associated medical problem resolution rates
Baseline characteristics of the native and immigrant patients.
<p><sup>1</sup>Patient born in the Netherlands and both parents born in the Netherlands</p><p><sup>2</sup> One or both parents born abroad</p><p>* Unpaired sample T-test</p><p>** Chi square test</p><p>*** Mann-Whitney U-test</p><p>Baseline characteristics of the native and immigrant patients.</p
Association of presence of absence of psychological distress with age, gender, ethnicity, immigrant status, quality of life, setting and specialism.
<p>* T-Test</p><p>** Chi square test</p><p>Association of presence of absence of psychological distress with age, gender, ethnicity, immigrant status, quality of life, setting and specialism.</p
Odds ratios for presence of psychological distress for immigrant patients versus native patients and first generation immigrant patients versus second generation immigrant patients.
<p>Odds ratios for presence of psychological distress for immigrant patients versus native patients and first generation immigrant patients versus second generation immigrant patients.</p