Mapping carcass and meat quality QTL on Sus Scrofa chromosome 2 in commercial finishing pigs

Quantitative trait loci (QTL) affecting carcass and meat quality located on SSC2 were identified using variance component methods. A large number of traits involved in meat and carcass quality was detected in a commercial crossbred population: 1855 pigs sired by 17 boars from a synthetic line, which where homozygous (A/A) for IGF2. Using combined linkage and linkage disequilibrium mapping (LDLA), several QTL significantly affecting loin muscle mass, ham weight and ham muscles (outer ham and knuckle ham) and meat quality traits, such as Minolta-L* and -b*, ultimate pH and Japanese colour score were detected. These results agreed well with previous QTL-studies involving SSC2. Since our study is carried out on crossbreds, different QTL may be segregating in the parental lines. To address this question, we compared models with a single QTL-variance component with models allowing for separate sire and dam QTL-variance components. The same QTL were identified using a single QTL variance component model compared to a model allowing for separate variances with minor differences with respect to QTL location. However, the variance component method made it possible to detect QTL segregating in the paternal line (e.g. HAMB), the maternal lines (e.g. Ham) or in both (e.g. pHu). Combining association and linkage information among haplotypes improved slightly the significance of the QTL compared to an analysis using linkage information only

Atacama Large Aperture Submillimeter Telescope (AtLAST) Science: Solar and stellar observations

Observations at (sub-)millimeter wavelengths offer a complementary perspective on our Sun and other stars, offering significant insights into both the thermal and magnetic composition of their chromospheres. Despite the fundamental progress in (sub-)millimeter observations of the Sun, some important aspects require diagnostic capabilities that are not offered by existing observatories. In particular, simultaneously observations of the radiation continuum across an extended frequency range would facilitate the mapping of different layers and thus ultimately the 3D structure of the solar atmosphere. Mapping large regions on the Sun or even the whole solar disk at a very high temporal cadence would be crucial for systematically detecting and following the temporal evolution of flares, while synoptic observations, i.e., daily maps, over periods of years would provide an unprecedented view of the solar activity cycle in this wavelength regime. As our Sun is a fundamental reference for studying the atmospheres of active main sequence stars, observing the Sun and other stars with the same instrument would unlock the enormous diagnostic potential for understanding stellar activity and its impact on exoplanets. The Atacama Large Aperture Submillimeter Telescope (AtLAST), a single-dish telescope with 50\,m aperture proposed to be built in the Atacama desert in Chile, would be able to provide these observational capabilities. Equipped with a large number of detector elements for probing the radiation continuum across a wide frequency range, AtLAST would address a wide range of scientific topics including the thermal structure and heating of the solar chromosphere, flares and prominences, and the solar activity cycle. In this white paper, the key science cases and their technical requirements for AtLAST are discussed.Comment: 14 pages, 4 figures, submitted to Open Research Europe as part of a collection on the Atacama Large Aperture Submillimeter Telescope (AtLAST

The key science drivers for the Atacama Large Aperture Submillimeter Telescope (AtLAST)

International audienceSub-mm and mm wavelengths provide a unique view of the Universe, from the gas and dust that fills and surrounds galaxies to the chromosphere of our own Sun. Current single-dish facilities have presented a tantalising view of the brightest (sub-)mm sources, and interferometers have provided the exquisite resolution necessary to analyse the details in small fields, but there are still many open questions that cannot be answered with current facilities: Where are all the baryons? How do structures interact with their environments? What does the time-varying (sub-)mm sky look like? In order to make major advances on these questions and others, what is needed now is a facility capable of rapidly mapping the sky spatially, spectrally, and temporally, which can only be done by a high throughput, single-dish observatory. An extensive design study for this new facility is currently being undertaken. In this paper, we focus on the key science drivers and the requirements they place on the observatory. As a 50m single dish telescope with a 1-2{\deg} field of view, the strength of the Atacama Large Aperture Submillimeter Telescope (AtLAST) is in science where a large field of view, highly multiplexed instrumentation and sensitivity to faint large-scale structure is important. AtLAST aims to be a sustainable, upgradeable, multipurpose facility that will deliver orders of magnitude increases in sensitivity and mapping speeds over current and planned telescopes

Atacama Large Aperture Submillimeter Telescope (AtLAST) Science: Resolving the Hot and Ionized Universe through the Sunyaev-Zeldovich effect

International audienceAn omnipresent feature of the multi-phase ``cosmic web'' is that warm/hot (>$10^5$ K) ionized gas pervades it. This gas constitutes a relevant contribution to the overall universal matter budget across multiple scales, from the several tens of Mpc-scale IGM filaments, to the Mpc ICM, all the way down to the CGM surrounding individual galaxies, on scales from ~1 kpc up to their respective virial radii (~100 kpc). The study of the hot baryonic component of cosmic matter density represents a powerful means for constraining the intertwined evolution of galactic populations and large-scale cosmological structures, for tracing the matter assembly in the Universe and its thermal history. To this end, the SZ effect provides the ideal observational tool for measurements out to the beginnings of structure formation. The SZ effect is caused by the scattering of the photons from the cosmic microwave background off the hot electrons embedded within cosmic structures, and provides a redshift-independent perspective on the thermal and kinematic properties of the warm/hot gas. Still, current and future (sub)mm facilities have been providing only a partial view of the SZ Universe due to any combination of: limited angular resolution, spectral coverage, field of view, spatial dynamic range, sensitivity. In this paper, we motivate the development of a wide-field, broad-band, multi-chroic continuum instrument for the Atacama Large Aperture Submillimeter Telescope (AtLAST) by identifying the scientific drivers that will deepen our understanding of the complex thermal evolution of cosmic structures. On a technical side, this will necessarily require efficient multi-wavelength mapping of the SZ signal with an unprecedented spatial dynamic range (from arcsecond to degree scales) and we employ theoretical forecasts to determine the key instrumental constraints for achieving our goals. [abridged

Atacama Large Aperture Submillimeter Telescope \mbox{(AtLAST)} Science: Probing the Transient and Time-variable Sky

International audienceThe study of transient and variable events, including novae, active galactic nuclei, and black hole binaries, has historically been a fruitful path for elucidating the evolutionary mechanisms of our universe. The study of such events in the millimeter and submillimeter is, however, still in its infancy. Submillimeter observations probe a variety of materials, such as optically thick dust, which are hard to study in other wavelengths. Submillimeter observations are sensitive to a number of emission mechanisms, from the aforementioned cold dust, to hot free-free emission, and synchrotron emission from energetic particles. Study of these phenomena has been hampered by a lack of prompt, high sensitivity submillimeter follow-up, as well as by a lack of high-sky-coverage submillimeter surveys. In this paper, we describe how the proposed Atacama Large Aperture Submillimeter Telescope (AtLAST) could fill in these gaps in our understanding of the transient universe. We discuss a number of science cases that would benefit from AtLAST observations, and detail how AtLAST is uniquely suited to contributing to them. In particular, AtLAST's large field of view will enable serendipitous detections of transient events, while its anticipated ability to get on source quickly and observe simultaneously in multiple bands make it also ideally suited for transient follow-up. We make theoretical predictions for the instrumental and observatory properties required to significantly contribute to these science cases, and compare them to the projected AtLAST capabilities. Finally, we consider the unique ways in which transient science cases constrain the observational strategies of AtLAST, and make prescriptions for how AtLAST should observe in order to maximize its transient science output without impinging on other science cases

Atacama Large Aperture Submillimeter Telescope (AtLAST) Science: Surveying the distant Universe

International audienceDuring the most active period of star formation in galaxies, which occurs in the redshift range 1<z<3, strong bursts of star formation result in significant quantities of dust, which obscures new stars being formed as their UV/optical light is absorbed and then re-emitted in the infrared, which redshifts into the mm/sub-mm bands for these early times. To get a complete picture of the high-z galaxy population, we need to survey a large patch of the sky in the sub-mm with sufficient angular resolution to resolve all galaxies, but we also need the depth to fully sample their cosmic evolution, and therefore obtain their redshifts using direct mm spectroscopy with a very wide frequency coverage. This requires a large single-dish sub-mm telescope with fast mapping speeds at high sensitivity and angular resolution, a large bandwidth with good spectral resolution and multiplex spectroscopic capabilities. The proposed 50-m Atacama Large Aperture Submillimeter Telescope (AtLAST) will deliver these specifications. We discuss how AtLAST allows us to study the whole population of high-z galaxies, including the dusty star-forming ones which can only be detected and studied in the sub-mm, and obtain a wealth of information for each of these up to z~7: gas content, cooling budget, star formation rate, dust mass, and dust temperature. We present worked examples of surveys that AtLAST can perform, both deep and wide, and also focused on galaxies in proto-clusters. In addition we show how such surveys with AtLAST can measure the growth rate and the Hubble constant with high accuracy, and demonstrate the power of the line-intensity mapping method in the mm/sub-mm wavebands to constrain the cosmic expansion history at high redshifts, as good examples of what can uniquely be done by AtLAST in this research field

Atacama Large Aperture Submillimeter Telescope (AtLAST) Science: Surveying the distant Universe

International audienceDuring the most active period of star formation in galaxies, which occurs in the redshift range 1<z<3, strong bursts of star formation result in significant quantities of dust, which obscures new stars being formed as their UV/optical light is absorbed and then re-emitted in the infrared, which redshifts into the mm/sub-mm bands for these early times. To get a complete picture of the high-z galaxy population, we need to survey a large patch of the sky in the sub-mm with sufficient angular resolution to resolve all galaxies, but we also need the depth to fully sample their cosmic evolution, and therefore obtain their redshifts using direct mm spectroscopy with a very wide frequency coverage. This requires a large single-dish sub-mm telescope with fast mapping speeds at high sensitivity and angular resolution, a large bandwidth with good spectral resolution and multiplex spectroscopic capabilities. The proposed 50-m Atacama Large Aperture Submillimeter Telescope (AtLAST) will deliver these specifications. We discuss how AtLAST allows us to study the whole population of high-z galaxies, including the dusty star-forming ones which can only be detected and studied in the sub-mm, and obtain a wealth of information for each of these up to z~7: gas content, cooling budget, star formation rate, dust mass, and dust temperature. We present worked examples of surveys that AtLAST can perform, both deep and wide, and also focused on galaxies in proto-clusters. In addition we show how such surveys with AtLAST can measure the growth rate and the Hubble constant with high accuracy, and demonstrate the power of the line-intensity mapping method in the mm/sub-mm wavebands to constrain the cosmic expansion history at high redshifts, as good examples of what can uniquely be done by AtLAST in this research field

Atacama Large Aperture Submillimeter Telescope (AtLAST) Science: Surveying the distant Universe

International audienceDuring the most active period of star formation in galaxies, which occurs in the redshift range 1<z<3, strong bursts of star formation result in significant quantities of dust, which obscures new stars being formed as their UV/optical light is absorbed and then re-emitted in the infrared, which redshifts into the mm/sub-mm bands for these early times. To get a complete picture of the high-z galaxy population, we need to survey a large patch of the sky in the sub-mm with sufficient angular resolution to resolve all galaxies, but we also need the depth to fully sample their cosmic evolution, and therefore obtain their redshifts using direct mm spectroscopy with a very wide frequency coverage. This requires a large single-dish sub-mm telescope with fast mapping speeds at high sensitivity and angular resolution, a large bandwidth with good spectral resolution and multiplex spectroscopic capabilities. The proposed 50-m Atacama Large Aperture Submillimeter Telescope (AtLAST) will deliver these specifications. We discuss how AtLAST allows us to study the whole population of high-z galaxies, including the dusty star-forming ones which can only be detected and studied in the sub-mm, and obtain a wealth of information for each of these up to z~7: gas content, cooling budget, star formation rate, dust mass, and dust temperature. We present worked examples of surveys that AtLAST can perform, both deep and wide, and also focused on galaxies in proto-clusters. In addition we show how such surveys with AtLAST can measure the growth rate and the Hubble constant with high accuracy, and demonstrate the power of the line-intensity mapping method in the mm/sub-mm wavebands to constrain the cosmic expansion history at high redshifts, as good examples of what can uniquely be done by AtLAST in this research field

Science development study for the Atacama Large Aperture Submillimeter Telescope (AtLAST):Solar and stellar observations

Observations at (sub-)millimeter wavelengths offer a complementary perspective on our Sun and other stars, offering significant insights into both the thermal and magnetic composition of their chromospheres. Despite the fundamental progress in (sub-)millimeter observations of the Sun, some important aspects require diagnostic capabilities that are not offered by existing observatories. In particular, simultaneously observations of the radiation continuum across an extended frequency range would facilitate the mapping of different layers and thus ultimately the 3D structure of the solar atmosphere. Mapping large regions on the Sun or even the whole solar disk at a very high temporal cadence would be crucial for systematically detecting and following the temporal evolution of flares, while synoptic observations, i.e., daily maps, over periods of years would provide an unprecedented view of the solar activity cycle in this wavelength regime. As our Sun is a fundamental reference for studying the atmospheres of active main sequence stars, observing the Sun and other stars with the same instrument would unlock the enormous diagnostic potential for understanding stellar activity and its impact on exoplanets. The Atacama Large Aperture Submillimeter Telescope (AtLAST), a single-dish telescope with 50m aperture proposed to be built in the Atacama desert in Chile, would be able to provide these observational capabilities. Equipped with a large number of detector elements for probing the radiation continuum across a wide frequency range, AtLAST would address a wide range of scientific topics including the thermal structure and heating of the solar chromosphere, flares and prominences, and the solar activity cycle. In this white paper, the key science cases and their technical requirements for AtLAST are discussed.</p