Las humanidades digitales y la base de datos MeMoRam: para un enfoque sistemático hacia los motivos en los libros de caballerías

The article highlights the latest developments in the field of Digital Humanities. It provides an excursus of some IT tools for scholars of Spanish Golden Age literature. The different units of the Mapping Chivalry project (PRIN 2017) are presented with special remarks about the database that is being developed in the Università di Trento (MeMoRam), focused on literary motifs. According to the study of Spanish chivalric literature, some recently created Motif-Indexes are introduced in order to investigate their theoretical approach to the concept of literary motif.En el artículo se valoran los avances de las Humanidades en el ámbito digital mediante un excursus acerca de las principales herramientas informáticas que están a disposición de los estudiosos, con especial atención a la literatura castellana del Siglo de Oro. Se presentan las distintas unidades que integran el proyecto Mapping Chivalry (PRIN 2017) con énfasis en la base de datos de los motivos caballerescos (MeMoRam), en fase de elaboración por la Università di Trento. Al respecto se propone un repaso de algunos índices creados en años recientes para el estudio de la literatura caballeresca hispánica y se presta atención al concepto de motivo adoptado en la elaboración de dichas herramientas

Personajes divergentes y motivos caballerescos: el caso de Lidamor de Escocia (1534), Valerián de Hungría (1540), Philesbián de Candaria (1542) y Cirongilio de Tracia (1545)

Description of PhD thesisFicha de la tesis de doctorado (defendida)Ficha de la tesis de doctorado (defendida

Presentación

Presentazione del numero 11 (2023) della rivista Historias FingidasPresentation of Historias fingidas 11 (2023)Presentación del número 11 (2023) de la revista Historias Fingida

Pulsed Radiofrequency as a Standalone Treatment for Adhesive Capsulitis

Adhesive capsulitis is a pathology that affects the shoulder and can have a particularly long and disabling course. The usual therapies are treatment with non-steroidal anti-inflammatory drugs (NSAID) and painkillers, steroid injections, physiotherapy, and surgical treatment. This case report describes the effect of a single treatment with pulsed radiofrequency of the suprascapular nerve in a diabetic patient affected by this pathology, for whom steroid injections were contraindicated. Three weeks after the treatment, the reduction of pain and the improvement of ROM (range of movement) allowed the patient to start an adequate physiotherapy treatment, which was not feasible until that moment due to the severe pain despite NSAIDS therapy. The peculiarity of this work consists in the accurate measure of the impact of the analgesic treatment alone in improving the ROM and muscular activation in the patient. The patient was able to correctly perform physiotherapy only once the pain was reduced, after PRF (pulsed radio frequency) treatment. This study has two limitations: being a case report and not a prospective randomized study, and observing the kinematic and pain aspects for a limited period of time. Finally, the case report draws attention to the importance of cooperation between the various health figures involved in the treatment of patients suffering from adhesive capsules

LA TRANSIZIONE ENERGETICA NELLA MACROREGIONE ALPINA: DEFINIZIONE DELLA SITUAZIONE DI PARTENZA

Nowadays energy transition is a recurring topic, which describes the process of an energy system moving from fossil-based sources towards renewables. The transition can unfold at different levels, from the single initiative of a local com-munity to a complex cross-border agreement. The latter type is well represented by EUSALP, the European macro-regional strategy for the Alpine region. One of its aims is to transform its territory into a model region for energy efficiency and renewable energy. To support a well-informed decision making process, this study provides the first insight about the status quo of energy balances in EUSALP, at local as well as aggregated level. Moreover, it offers an overview on the various energy targets defined by the territorial units that constitute the EUSALP region. Data has been retrieved via a bottom-up quality-oriented process consisting of (i) a survey targeted at responsible person in local energy departments; and (ii) data control and harmonization. We found that the EUSALP region is actually a model region only in clean power production, whereas starting point as well as energy targets of territories are highly heterogeneous. We al-so identified the need of more harmonized data collection methodologies. We conclude that this bottom-up process can support and legitimate policy makers in cross-border cooperation activities under a smart macro-regional energy strategy, which pursues an increment in energy savings, renewable energy production and a broad engagement of relevant stakeholders. DOI: http://dx.medra.org/10.19254/LaborEst.16.1

LA TRANSIZIONE ENERGETICA NELLA MACROREGIONE ALPINA: DEFINIZIONE DELLA SITUAZIONE DI PARTENZA

Nowadays energy transition is a recurring topic, which describes the process of an energy system moving from fossil-based sources towards renewables. The transition can unfold at different levels, from the single initiative of a local com-munity to a complex cross-border agreement. The latter type is well represented by EUSALP, the European macro-regional strategy for the Alpine region. One of its aims is to transform its territory into a model region for energy efficiency and renewable energy. To support a well-informed decision making process, this study provides the first insight about the status quo of energy balances in EUSALP, at local as well as aggregated level. Moreover, it offers an overview on the various energy targets defined by the territorial units that constitute the EUSALP region. Data has been retrieved via a bottom-up quality-oriented process consisting of (i) a survey targeted at responsible person in local energy departments; and (ii) data control and harmonization. We found that the EUSALP region is actually a model region only in clean power production, whereas starting point as well as energy targets of territories are highly heterogeneous. We al-so identified the need of more harmonized data collection methodologies. We conclude that this bottom-up process can support and legitimate policy makers in cross-border cooperation activities under a smart macro-regional energy strategy, which pursues an increment in energy savings, renewable energy production and a broad engagement of relevant stakeholders

Gambling at the time of COVID-19: results from interviews in an Italian sample of gamblers

© 2022 The Author(s). Published by Elsevier Ltd on behalf of International Society for the Study of Emerging Drugs. https://creativecommons.org/licenses/by/4.0/The coronavirus pandemic affected the life of those suffering from addic- tive behaviors often confined to prolonged periods of self-isolation. To explore the variation of symptoms related to gambling, 46 outpatients of the mental health services in the Trento Province were invited to take part in a phone interview at the start of the national lockdown. Although only 2.17% increased gambling activity during this period, half of the sample (50.00%) experienced irritability, mood fluctuation (43.48%) and anxiety (39.13%). Follow-up studies should assess modifications in their behaviors that occurred after the reopening of gambling venues.Peer reviewedFinal Published versio

Home-based pulmonary rehabilitation in patients undergoing (chemo)radiation therapy for unresectable lung cancer: a prospective explorative study

Aims The prevention of pulmonary toxicity is an important goal for patient candidate to radiation therapy for lung cancer. There is a lack of evidence on the role of exercise training for patients with unresectable stage III lung cancer candidated to radical treatment. The aim of this study was to evaluate the feasibility of a home-based pulmonary rehabilitation (PR) program and to identify reliable tools in terms of respiratory function, exercise capacity and quality of life. Methods Patients' recruitment lasted from April 2020 till February 2022. The PR program was proposed concomitantly to radiation therapy to the first 20 patients (interventional group, IG), and the other 20 patients were identified as an observational group (OG). All patients were assessed at baseline (T0) and after 8 weeks (T2) with 6 minute walking test (6MWT), modified Borg Scale (mBORG), SF-36 questionnaire (SF-36) and pulmonary function test (PFT); after 4 weeks (T1), only SF-36 was administered. Results A decrease of 13.8 m in the walked-distance was registered in the OG between T0 and T2 (p = 0.083). Instead, an increase of 56.6 m in the distance walked was recorded in the IG between T0 and T2 (p <= 0.001). In the OG, the mBORG scores showed a negative trend. On the contrary, in the IG, these scores showed a slight improvement. In the OG, all the items of SF-36 scores decreased between T0 and T1. In the IG, an increased trend from T0 to T2 was observed for all the items of SF-36. No clinically significant variations were detected from baseline to T2 in both groups regarding PFT. Conclusion The 6MWT, mBORG and SF-36 resulted as useful tools to assess the role of a PR program. A significant gain in functional exercise capacity and a prevention of the physiological impairment of QoL during radio(chemo)therapy was registered

Phthalates and Bisphenol A: presence in blood serum and follicular fluid of italian women undergoing assisted reproduction techniques

Background: folliculogenesis is a strictly regulated process that may be affected by endocrine disrupting chemicals (EDCs) through sometimes not so clear molecular mechanisms. Methods: we conducted a multicentric observational study involving six fertility centers across Italy, prospectively recruiting 122 women attending a fertility treatment. Recruited women had age ≤42 years, and normal ovarian reserve. Blood and follicular fluid samples were taken for EDCs measurement using liquid chromatography tandem mass spectrometry and each woman completed an epidemiological questionnaire. Results: The main EDCs found were monobutyl phthalate (MBP) (median blood: 8.96 ng/mL, follicular fluid 6.43 ng/mL), monoethylhexyl phthalate (MEHP) (median blood: 9.16 ng/mL, follicular fluid 7.68 ng/mL) and bisphenol A (BPA) (median blood: 1.89 ng/mL, follicular fluid 1.86 ng/mL). We found that serum MBP concentration was significantly associated with the considered area (p &lt; 0.001, adj. mean: 7.61 ng/mL, 14.40 ng/mL, 13.56 ng/mL; Area 1: Milan–Turin, Area 2: Rome–Naples; Area 3: Catania–Bari, respectively) but negatively with home plastic food packaging (p = 0.004). Follicular MBP was associated with irregular cycles (p = 0.019). No association was detected between EDCs and eating habits and other clinical and epidemiological features. Conclusions: This study represents the first Italian biomonitoring of plastic EDCs in follicular fluid, laying the basis for future prospective evaluation on oocyte quality before assisted reproduction techniques (ART

Retinal microvascular alterations in patients with active rheumatoid arthritis without cardiovascular risk factors: the potential effects of T cell co-stimulation blockade

BackgroundThe evaluation of microvascular alterations might provide clinically useful information for patients with an increased cardiovascular (CV) risk, such as those with rheumatoid arthritis (RA), being the small artery remodeling the earliest form of target organ damage in primary CV diseases, such as arterial hypertension. The evaluation of retinal arterioles is a non-invasive technique aimed to identify an early microvascular damage, represented by the increase of the wall-to-lumen ratio (WLR) index. Abatacept (ABA), a T-cell co-stimulator blocker, is used to treat RA. A CV protective action was hypothesized for its peculiar mechanism of action in the modulation of T-cells, potentially involved in the pathogenesis of CV comorbidity. The study aimed to non-invasively investigate morphological characteristics of retinal arterioles in a cohort of RA patients treated with ABA.Materials and methodsSeventeen RA patients [median (25th-75thpercentile) age = 58 (48–64) years, baseline 28-joint Disease Activity Score DAS28-C-reactive protein (DAS28-CRP) = 4.4 (3.9–4.6), body mass index (BMI) = 24.2 (23.4–26) kg/m2, rheumatoid factor positive:52.9%, anti-citrullinated peptide autoantibodies positive:76.5%] without known CV risk factors (arterial hypertension, diabetes, hypercholesterolemia, previous CV events, smoking) were evaluated by the adaptive optics imaging system of retinal arterioles before and every 6 months of therapy with ABA (T0, T6 and T12). Office blood pressure evaluation, 24-h ambulatory blood pressure monitoring and tissue-doppler echocardiography were also performed.ResultsA progressive significant reduction of the WLR of retinal arterioles was observed [T0 = 0.28 (0.25–0.30), T6 = 0.27 (0.24–0.31), T12 = 0.23 (0.23–0.26); p T0 vs. T6 = 0.414; p T6 vs. T12 = 0.02; p T0 vs. T12 = 0.009], without significant variations in other parameters. The T0-T12 reduction of WLR was correlated with that of DAS28-CRP (r:0.789; p = 0.005). Moreover, a significant reduction of diastolic office blood pressure and a trend for reduction of daily pressure measured by ambulatory monitoring were observed.ConclusionIn a cohort of RA patients without known CV risk factors, a reduction of retinal microvascular alterations was demonstrated after treatment for 12 months with ABA, in parallel with the reduction of disease activity. These results might suggest the possibility of microvascular abnormalities regression induced by the immune system modulation