X.509 certificate error testing

X.509 Certificates are used by a wide range of technologies to verify identities, while the SSL protocol is used to provide a secure encrypted tunnel through which data can be sent over a public network. Combined both of these technologies provides the basis of the public key infrastructure (PKI). While the concept of PKI is a good idea, the different implementation of the technologies in different operating system and clients often lead to weaknesses. This paper proposes a methodology to automate the testing of SSL clients by generating both bogus and malformed certificates in order to evaluate the client’s response and identify potential threats to network infrastructures

The Semantics and Pragmatics of Right Dislocation: Odd thing, that.

The sentence "She's a smart one, that Diana" is a so-called right dislocation construction: the noun phrase "that Diana" occurs at the right edge of the sentence and the sentence itself only realizes a pronoun ("she") to refer to Diana. This construction is particularly common among British English speakers. Whereas prior research has focused on the structure and interpretation of the construction, my research explores the hypothesis that speakers use the construction when they expect their interlocutors to agree with them about the propositional content of the utterance (e.g., that Diana is a smart person, in the aforementioned example). In summer 2017 I ran an experiment with 38 native British English speakers, administering a survey in which each participant rated the acceptability of a target sentence in context on a 6-point Likert scale. Target sentences varied minimally between right dislocated and non-dislocated variants, and contexts were either such that the speaker would expect the listener to agree with the propositional content of the utterance, or such that the speaker would expect the listener to disagree. Each target sentence was judged within both contexts. While no significant difference was found between the agree and disagree contexts among the right dislocated target sentences as a whole, the variation in response patterns both between participants and between items reveal potential routes for further exploration of right dislocation constructions' social meaning in the future.Arts & Sciences Undergraduate Research ScholarshipArts & Sciences International Research GrantNo embargoAcademic Major: ChineseAcademic Major: Linguistic

Oscillations of the intertropical convergence zone and the genesis of easterly waves

We examine the eastern Pacific Ocean Intertropical Convergence Zone (ITCZ) both in its mean state and transient phases using a combined diagnostic, theoretical and numerical modeling approach. We note that the ITCZ is perpetually in a transient state with strong variability occurring on 4-8 day time scales. Transients, about half the amplitude of the mean ITCZ, propagate northwards from the near-equatorial southern hemisphere eventually increasing the convection in the vicinity of the mean ITCZ convection. It is argued that the mean ITCZ is continually inertially unstable with incursions of anticyclonic vorticity advected across the equator resulting in the creation of a divergence-convergence doublet. The low-level convergence generates convection and vortex tube stretching which generates cyclonic vorticity counteracting the northward advection of anticyclonic vorticity. During a cycle, the heating in the mid-troposphere near 10°N oscillated between 6 and 12 K/day at the inertial frequency of the latitude of the mean convection. The shallow meridional circulation, noted in the mean field in other studies, appears to be a result of the transient nature of the ITCZ. It is hypothesized that westward propagating equatorial waves result from the inertial oscillation of the ITCZ. To test that the waves are formed in situ in the eastern Pacific and not remnants of waves propagating from the Atlantic or promoted by the Central and South American orography, several numerical experiments are undertaken using a high-resolution regional model spanning the western Atlantic Ocean and the eastern Pacific. In the control case, the model is initialized at all boundaries with full high-frequency observations. In two additional experiments, these transients are filtered out, and a third experiment is run with the topography over a large part of Central and South America removed. In all experiments, westward propagating waves are formed in the region of high CEPG suggesting that the hypothesis of in situ development may be correct.Ph.D.Committee Chair: Peter J. Webster; Committee Member: Robert X. Black; Committee Member: John A. Knox; Committee Member: Judith A. Curry; Committee Member: Yi Den

Direct Detection of Leptophilic Dark Matter in a Model with Radiative Neutrino Masses

We consider an electro-weak scale model for Dark Matter (DM) and radiative neutrino mass generation. Despite the leptophilic nature of DM with no direct couplings to quarks and gluons, scattering with nuclei is induced at the 1-loop level through photon exchange. Effectively, there are charge-charge, dipole-charge and dipole-dipole interactions. We investigate the parameter space consistent with constraints from neutrino masses and mixing, charged lepton-flavour violation, perturbativity, and the thermal production of the correct DM abundance, and calculate the expected event rate in DM direct detection experiments. We show that current data from XENON100 start to constrain certain regions of the allowed parameter space, whereas future data from XENON1T has the potential to significantly probe the model.Comment: 24 pages, 8 figures, 2 tables, discussion of large theta13 added, version to appear in PR

Economic and environmental analysis of the introduction of legumes in livestock farming systems

Legumes in low input systems are becoming increasingly important. The socioeconomic implication of the adoption of novel legumes species has been assessed in sheep and dairy cattle grazing systems in Europe using a biological model which has been linked to linear programming models. In the economic sub-model, the mathematical programming models produce an economic evaluation of the legumes in a farming system context, emphasising the land allocation and the availability of nutrients during the different seasons of the production cycle. Then the paper evaluates the impact of adopting the legumes on the regional income and production. In the UK and Germany, the introduction of legumes results in sizeable gains for the farmers whereas in Italy and France the gains are smaller

An In-Depth Computational Study of Alkene Cyclopropanation Catalyzed by Fe(porphyrin)(OCH3) Complexes. The Environmental Effects on the Energy Barriers

Iron porphyrin methoxy complexes, of the general formula [Fe(porphyrin)(OCH3)], are able to catalyze the reaction of diazo compounds with alkenes to give cyclopropane products with very high efficiency and selectivity. The overall mechanism of these reactions was thoroughly investigated with the aid of a computational approach based on density functional theory calculations. The energy profile for the processes catalyzed by the oxidized [FeIII(Por)(OCH3)] (Por = porphine) as well as the reduced [FeII(Por)(OCH3)]- forms of the iron porphyrin was determined. The main reaction step is the same in both of the cases, that is, the one leading to the terminal-carbene intermediate [Fe(Por)(OCH3)(CHCO2Et)] with simultaneous dinitrogen loss; however, the reduced species performs much better than the oxidized one. Contrarily to the iron(III) profile in which the carbene intermediate is directly obtained from the starting reactant complex, the favored iron(II) process is more intricate. The initially formed reactant adduct between [FeII(Por)(OCH3)]- and ethyl diazoacetate (EDA) is converted into a closer reactant adduct, which is in turn converted into the terminal iron porphyrin carbene [Fe(Por)(OCH3)(CHCO2Et)]-. The two corresponding transition states are almost isoenergetic, thus raising the question of whether the rate-determining step corresponds to dinitrogen loss or to the previous structural and electronic rearrangement. The ethylene addition to the terminal carbene is a downhill process, which, on the open-shell singlet surface, presents a defined but probably short-living diradicaloid intermediate, though other spin-state surfaces do not show this intermediate allowing a direct access to the cyclopropane product. For the crucial stationary points, the more complex catalyst [Fe(2)(OCH3)], in which a sterically hindered chiral bulk is mounted onto the porphyrin, was investigated. The corresponding computational data disclose the very significant effect of the porphyrin skeleton on the reaction energy profile. Though the geometrical features around the reactive core of the system remain unchanged, the energy barriers become much lower, thus revealing the profound effects that can be exerted by the three-dimensional organic scaffold surrounding the reaction site.

Molecular and behavioral mechanisms mediating paclitaxel-induced changes in affect-like behavior in mice

The antineoplastic paclitaxel is associated with negative affective outcomes, such as depression, anxiety, and decreased quality of life during treatment and convalescence. With the Baby Boomer population approaching peak cancer age, it is dire that the mechanisms behind paclitaxel-induced changes in mood are uncovered. Cancer-free male and female C57BL/6J mice were treated with one set of four injections of vehicle or paclitaxel (32mg/kg cumulative), or two sets of four injections of vehicle or paclitaxel (64mg/kg cumulative), and periodically assessed for depression-like behaviors. Paclitaxel caused significant, time-dependent deficits in sucrose preference and operant responding for palatable food. Because there is growing evidence to support the role of kappa opioid receptors (KORs) in stress-mediated depression and reward dysfunction, we investigated KOR signaling as a putative mechanism of paclitaxel-induced depression-like behaviors. The selective KOR antagonist norbinaltorphimine (norBNI) reversed paclitaxel-induced attenuation of sucrose preference. At the molecular level, paclitaxel time-dependently induced an increase in the expression of Prodynorphin mRNA, the precursor for endogenous KOR agonists, in the nucleus accumbens (NAc). Using the [35S]GTPγS assay, we discovered that a history of paclitaxel time-dependently attenuated activation of dopamine D2 receptors (D2R) and KORs in the NAc but not caudate putamen. These data suggest that paclitaxel-induced changes in affect-like behavior may be due to time- and region-dependent dysregulation of KOR and D2R signaling. These observations help to establish the roles of KOR and D2R systems in paclitaxel-induced disruption of behavioral reward, thus revealing potential neurochemical targets for therapeutic intervention in cancer survivors with treatment-resistant depression.https://scholarscompass.vcu.edu/gradposters/1038/thumbnail.jp

Unstable GRB photospheres and electron-positron annihilation lines

We propose an emission mechanism of prompt gamma-ray bursts (GRBs) that can reproduce the observed non-thermal spectra with high radiative efficiencies, >50%. Internal dissipation below a photosphere can create a radiation-dominated thermal fireball. If electron-positron pairs outnumber protons, radiative acceleration of pairs drives the two-stream instabilities between pairs and protons, leading to the ``proton sedimentation'' in the accelerating pair frame. Pairs are continuously shock heated by proton clumps, scattering the thermal photons into the broken power-law shape, with the non-thermal energy that is comparable to the proton kinetic energy, consistent with observations. Pair photospheres become unstable around the radius of the progenitor star where strong thermalization occurs, if parameters satisfy the observed spectral (Yonetoku) relation. Pair annihilation lines are predicted above continua, which could be verified by GLAST.Comment: 4 pages, 2 figure

A case of acute aortic dissection type b associated with cushing's syndrome

We report a case of a 63-year-old man, with a previous history of hypertension and glucose intolerance associated troncular obesity that was emergently admitted to our Institution for evaluation of a severe, constant posterior chest pain which radiated anteriorly and dyspnoea with a suspected diagnosis of acute aortic dissection. A CT scan of thorax and abdomen demonstrated a dissection starting just below left succlavian artery and extending downward to the left renal artery, involving the celiac tripod and superior mesenteric artery. The dissection was classified as Stanford B, De Bakey III. Moreover, CT scan of abdomen revealed incidentally a left adrenal tumor of 25 mm of diameter. An emergent prosthetic graft was placed just below the origin of the left succlavian artery up-to the diaphragmatic hiatus. Furthermore, a diagnostic evaluation of the mass revealed an increase of cortisol production, and a diagnosis of Cushing's syndrome was done and the patient underwent an adrenalectomy via laparotomic approach. We report an association of acute aortic dissection of acute aortic dissection type B associated to Cushing's syndrome. Cushing's syndrome; Adrenocortical adenoma; Aortic dissection type B