40 research outputs found

    On the effect of projections on convergence peak counts and Minkowski functionals

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    The act of projecting data sampled on the surface of the celestial sphere onto a regular grid on the plane can introduce error and a loss of information. This paper evaluates the effects of different planar projections on non-Gaussian statistics of weak lensing convergence maps. In particular we investigate the effect of projection on peak counts and Minkowski Functionals (MFs) derived from convergence maps and the suitability of a number of projections at matching the peak counts and MFs obtained from a sphere. We find that the peak counts derived from planar projections consistently overestimate the counts at low SNR thresholds and underestimate at high SNR thresholds across the projections evaluated, although the difference is reduced when smoothing of the maps is increased. In the case of the Minkowski Functionals, V0 is minimally affected by projection used, while projected V1 and V2 are consistently overestimated with respect to the spherical case

    A filament of dark matter between two clusters of galaxies

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    It is a firm prediction of the concordance Cold Dark Matter (CDM) cosmological model that galaxy clusters live at the intersection of large-scale structure filaments. The thread-like structure of this "cosmic web" has been traced by galaxy redshift surveys for decades. More recently the Warm-Hot Intergalactic Medium (WHIM) residing in low redshift filaments has been observed in emission and absorption. However, a reliable direct detection of the underlying Dark Matter skeleton, which should contain more than half of all matter, remained elusive, as earlier candidates for such detections were either falsified or suffered from low signal-to-noise ratios and unphysical misalignements of dark and luminous matter. Here we report the detection of a dark matter filament connecting the two main components of the Abell 222/223 supercluster system from its weak gravitational lensing signal, both in a non-parametric mass reconstruction and in parametric model fits. This filament is coincident with an overdensity of galaxies and diffuse, soft X-ray emission and contributes mass comparable to that of an additional galaxy cluster to the total mass of the supercluster. Combined with X-ray observations, we place an upper limit of 0.09 on the hot gas fraction, the mass of X-ray emitting gas divided by the total mass, in the filament.Comment: Nature, in pres

    Characterization of morbilliviruses isolated from dolphins and porpoises in Europe.

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    A previously unidentified morbillivirus was isolated from two harbour porpoises (Phocoena phocoena) that had died in the Dutch Waddensea (North Sea) in 1990. This porpoise morbillivirus (PMV) and a dolphin morbillivirus (DMV), which had recently caused a heavy mortality in Mediterranean striped dolphins (Stenella coeruleoalba), were compared antigenically with other members of the genus Morbillivirus, including the newly recognized phocine distemper virus type 1. DMV and PMV proved to be similar but distinct morbilliviruses, closely related to rinderpest virus and peste-des-petits-ruminants virus. Cell cultures of cetacean, pinniped, ruminant and canine origin showed a different pattern of susceptibility to DMV and PMV infection. Ruminants and dogs proved to be susceptible to experimental infection with DMV and PMV, which both caused a transient leukopenia most pronounced in the ruminants. Pre-exposure of dogs to DMV and PMV protected them from developing CDV viraemia and clinical signs upon challenge infection with virulent CDV. A serological survey among stranded animals of different cetacean species in Europe indicated that infections with DMV- and PMV-like morbilliviruses are not uncommon among these aquatic mammals

    Deletions in VANGL1 are a risk factor for antibody-mediated kidney disease

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    We identify an intronic deletion in VANGL1 that predisposes to renal injury in high risk populations through a kidney-intrinsic process. Half of all SLE patients develop nephritis, yet the predisposing mechanisms to kidney damage remain poorly understood. There is limited evidence of genetic contribution to specific organ involvement in SLE.(1,2) We identify a large deletion in intron 7 of Van Gogh Like 1 (VANGL1), which associates with nephritis in SLE patients. The same deletion occurs at increased frequency in an indigenous population (Tiwi Islanders) with 10-fold higher rates of kidney disease compared with non-indigenous populations. Vangl1 hemizygosity in mice results in spontaneous IgA and IgG deposition within the glomerular mesangium in the absence of autoimmune nephritis. Serum transfer into B cell-deficient Vangl1(+/-) mice results in mesangial IgG deposition indicating that Ig deposits occur in a kidney-intrinsic fashion in the absence of Vangl1. These results suggest that Vangl1 acts in the kidney to prevent Ig deposits and its deficiency may trigger nephritis in individuals with SLE

    Mission-level performance verification approach for the Euclid space mission

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    ESA's Dark Energy Mission Euclid will map the 3D matter distribution in our Universe using two Dark Energy probes: Weak Lensing (WL) and Galaxy Clustering (GC). The extreme accuracy required for both probes can only be achieved by observing from space in order to limit all observational biases in the measurements of the tracer galaxies. Weak Lensing requires an extremely high precision measurement of galaxy shapes realised with the Visual Imager (VIS) as well as photometric redshift measurements using near-infrared photometry provided by the Near Infrared Spectrometer Photometer (NISP). Galaxy Clustering requires accurate redshifts (∆z/(z+1)<0.1%) of galaxies to be obtained by the NISP Spectrometer. Performance requirements on spacecraft, telescope assembly, scientific instruments and the ground data-processing have been carefully budgeted to meet the demanding top level science requirements. As part of the mission development, the verification of scientific performances needs mission-level end-to-end analyses in which the Euclid systems are modeled from as-designed to final as-built flight configurations. We present the plan to carry out end-to-end analysis coordinated by the ESA project team with the collaboration of the Euclid Consortium. The plan includes the definition of key performance parameters and their process of verification, the input and output identification and the management of applicable mission configurations in the parameter database

    The relationship between sensory processing sensitivity and attention deficit hyperactivity disorder traits : a spectrum approach

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    The aim of the present study was to examine the relationship between sensory processing sensitivity (SPS) and symptoms of Attention Deficit Hyperactivity Disorder (ADHD) in adults. The Highly Sensitive Person Scale (HSPS) scale and the Adult ADHD Self-Report Scale (ASRS) were administered to a non-clinical group of 274 participants recruited from a university volunteers list. We found a highly significant positive correlation between number of self-reported ADHD traits and sensory sensitivity. Furthermore, ADHD traits and age were predictors of SPS and exploratory factor analysis revealed a factor that combined ADHD traits and items from the HSPS. The psychometric properties of the HSPS were also examined supporting the unidimensional nature of the concept. To our knowledge, this is the first study to identify a positive relationship between HSPS and ADHD traits in the general population. Our results further support recent findings suggesting abnormal sensory processing in ADHD

    Sulfur-Directed Olefin Oxidations: Observation of Divergent Reaction Mechanisms in the Palladium-Mediated Acetoxylation of Unsaturated Thioacetals

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    The Pd-mediated oxidation of unsaturated thioacetals gives either allyl or vinyl esters, depending on the substrate structure. We report the characterization of a range of sulfur-stabilized palladium intermediates via a combined computational and experimental NMR approach, demonstrating that the oxidation proceeds via two divergent reaction mechanisms. We were also able to synthesize an unusual sigma-bound Pd complex, via acetoxypalladation of an unsaturated dithiane, which was characterized by X-ray crystallography
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