A Computational Investigation into the Authorship of Sister Peg

Peer reviewe

The effect of investment constraints on hedge fund investor returns

This paper examines the effect of investor-level real-world investment constraints, including several which had not been studied before, on hedge fund performance and its persistence. Using a large consolidated database, we demonstrate that hedge fund performance persistence is significantly reduced when rebalancing rules reflect fund size restrictions and liquidity constraints, but remains statistically significant at higher rebalancing frequencies. Hypothetical investor portfolios that incorporate additional minimum diversification constraints and minimum investment requirements suggest that the performance and its persistence documented in earlier studies of hedge funds is not easily exploitable, especially by large investors

Examining the Early Modern Canon : The English Short Title Catalogue and Large-Scale Patterns of Cultural Production

Peer reviewe

Reconstructing intellectual networks : From the ESTC’s bibliographic metadata to historical material

Peer reviewe

Using multiple imputation and intervention-based scenarios to project the mobility of older adults

Background: Projections of the development of mobility limitations of older adults are needed for evidence-based policy making. The aim of this study was to generate projections of mobility limitations among older people in the United States, England, and Finland. Methods: We applied multiple imputation modelling with bootstrapping to generate projections of stair climbing and walking limitations until 2026. A physical activity intervention producing a beneficial effect on self-reported activities of daily living measures was identified in a comprehensive literature search and incorporated in the scenarios used in the projections. We utilised the harmonised longitudinal survey data from the Ageing Trajectories of Health – Longitudinal Opportunities and Synergies (ATHLOS) project (N = 24,982). Results: Based on the scenarios from 2012 to 2026, the prevalence of walking limitations will decrease from 9.4 to 6.4%. A physical activity intervention would decrease the prevalence of stair climbing limitations compared with no intervention from 28.9 to 18.9% between 2012 and 2026. Conclusions: A physical activity intervention implemented on older population seems to have a positive effect on maintaining mobility in the future. Our method provides an interesting option for generating projections by incorporating intervention-based scenarios

Trends in mental health diagnosis and use of resources in Europe during the COVID-19 pandemic

Background: The European Population Health Information Research Infraestructure (PHIRI) conducted research through use cases of applicability for public health policies during the COVID-19 pandemic. The aim of this study is to present changes in diagnosis of depression or anxiety and the use of health services before and during the COVID-19 crisis. Methods: Aggregated datasets with the total number of diagnosis of depression or anxiety (ICD10: F30-F39 and F40-F48 codes) and the number of visits to primary care, hospital or emergency department were generated were generated. Diagnoses were obtained from electronic health records in Austria, Estonia, Finland, Croatia, Latvia, Romania and Aragon (Spain), using the PHIRI federated research infra structure. Incident trends were depicted by month and year of visit (2017 and 2020). Results: Overall, 1,514,311 diagnoses of depression or anxiety were reported in 2017 vs. 1,102,468 diagnoses in 2020. By countries, monthly mean diagnosis of depression or anxiety ranged 2.7/10000 population (standard deviation, SD:0.2) to 148.4(20.0) for 2017; after lockdown in 2020 incidence decreased in most countries. Visits to primary, specialized care and emergency related to anxiety and depression diagnoses dropped after lockdown but they increased in general in all countries during 2021. Conclusions: Despite differences in the European health systems, a slight impact on COVID-19 on mental health diagnoses could be detected. This study highlights the potential use of harmonized data for providing evidence for future pandemic preparedness. Key messages: The use of a federated research infrastructure has allowed assessing the impact of COVID-19 in mental health across European countries in a harmonized way. Slight changes in mental health diagnoses and use of resources could be detected in several European countries due to COVID-19 pandemic.S