9 research outputs found
ΠΠΏΠ»ΠΈΠ² L-ΠΊΠ°ΡΠ½ΡΡΠΈΠ½Ρ Π½Π° ΠΏΠΎΠΊΠ°Π·Π½ΠΈΠΊΠΈ Π΅Π½Π΄ΠΎΡΠ΅Π»ΡΠ°Π»ΡΠ½ΠΎΡ Π΄ΠΈΡΡΡΠ½ΠΊΡΡΡ Ρ ΡΠ°ΠΊΡΠΎΡΠΈ Π·Π°ΠΏΠ°Π»Π΅Π½Π½Ρ Π² ΠΏΠ°ΡΡΡΠ½ΡΡΠ² ΡΠ· Π³ΠΎΡΡΡΠΈΠΌ ΡΠ½ΡΠ°ΡΠΊΡΠΎΠΌ ΠΌΡΠΎΠΊΠ°ΡΠ΄Π° Π±Π΅Π· Π·ΡΠ±ΡΡ Q
Aim: To evaluate the influence of L-carnitine on inflammatory markers and indicators of endothelial function in patientsΒ with acute myocardial infarction without the Q wave.Materials and Methods: 40 patients with verified diagnosis of AMI without Q-wave. All the patients were matchedΒ by sex, age, weight and duration of the underlying disease. The patients were randomized into 2 groups. The first group ofpatients were on a standard basic therapy and additionally administered L- carnitine at a dose 5g/day, II- group consisted ofΒ patients who did not receive drugs with metabolic action. In dynamics (on the 1st and 10th day of the treatment) the parametersΒ of endothelium vasodilation and markers of inflammation were evaluated.Results: On the background of the basic therapy in both groups an improvement in endothelial function resulting in an increase of brachial artery diameter was observed. However, the L- carnitine vasodilator effect was more pronounced and persistent as compared to group II. In the dynamics, CRP levels and plasma fibrinogen were more pronounced in the Ist group.Π‘ ΡΠ΅Π»ΡΡ ΠΎΡΠ΅Π½ΠΊΠΈ Π²Π»ΠΈΡΠ½ΠΈΡ L-ΠΊΠ°ΡΠ½ΠΈΡΠΈΠ½Π° Π½Π°Β ΠΌΠ°ΡΠΊΠ΅ΡΡ Π²ΠΎΡΠΏΠ°Π»Π΅Π½ΠΈΡ ΠΈ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ ΡΠ½Π΄ΠΎΡΠ΅Π»ΠΈΠ°Π»ΡΠ½ΠΎΠΉ ΡΡΠ½ΠΊΡΠΈΠΈ Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΠΎΡΡΡΡΠΌ ΠΈΠ½ΡΠ°ΡΠΊΡΠΎΠΌΒ ΠΌΠΈΠΎΠΊΠ°ΡΠ΄Π°(ΠΠΠ) Π±Π΅Π· Π·ΡΠ±ΡΠ° Q ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΎ 40 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΡΡΡΠΈΠΌ Π΄ΠΈΠ°Π³Π½ΠΎΠ·ΠΎΠΌ. ΠΡΡΠ²Π»Π΅Π½ Π±ΠΎΠ»Π΅Π΅ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΡΠΉ Π²Π°Π·ΠΎΠ΄ΠΈΠ»Π°ΡΠΈΡΡΡΡΠΈΠΉ ΡΡΡΠ΅ΠΊΡ Π² Π³ΡΡΠΏΠΏΠ΅ L-ΠΊΠ°ΡΠ½ΠΈΡΠΈΠ½Π° Ρ ΠΏΠ°ΡΠ°Π»Π»Π΅Π»ΡΠ½ΡΠΌ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΠ΅ΠΌ ΡΡΠΎΠ²Π½Ρ ΠΌΠ°ΡΠΊΠ΅ΡΠΎΠ² ΡΠΈΡΡΠ΅ΠΌΠ½ΠΎΠ³ΠΎ Π²ΠΎΡΠΏΠ°Π»Π΅Π½ΠΈΡ.Β Π ΠΌΠ΅ΡΠΎΡ ΠΎΡΡΠ½ΠΊΠΈ Π²ΠΏΠ»ΠΈΠ²Ρ L-ΠΊΠ°ΡΠ½ΡΡΠΈΠ½Ρ Π½Π° ΠΌΠ°ΡΠΊΠ΅ΡΠΈ Π·Π°ΠΏΠ°Π»Π΅Π½Π½Ρ ΡΠ° ΠΏΠΎΠΊΠ°Π·Π½ΠΈΠΊΠΈ Π΅Π½Π΄ΠΎΡΠ΅Π»ΡΠ°Π»ΡΠ½ΠΎΡ ΡΡΠ½ΠΊΡΡΡ Π² ΠΏΠ°ΡΡΡΠ½ΡΡΠ² ΡΠ· Π³ΠΎΡΡΡΠΈΠΌ ΡΠ½ΡΠ°ΡΠΊΡΠΎΠΌ ΠΌΡΠΎΠΊΠ°ΡΠ΄Π°(ΠΠΠ) Π±Π΅Π· Π·ΡΠ±ΡΡ Q ΠΎΠ±ΡΡΠ΅ΠΆΠ΅Π½ΠΎ 40 ΠΏΠ°ΡΡΡΠ½ΡΡΠ² Π· Π²ΡΠ΄ΠΏΠΎΠ²ΡΠ΄Π½ΠΈΠΌ Π΄ΡΠ°Π³Π½ΠΎΠ·ΠΎΠΌ. ΠΠΈΡΠ²Π»Π΅Π½ΠΈΠΉ Π±ΡΠ»ΡΡ Π²ΠΈΡΠ°ΠΆΠ΅Π½ΠΈΠΉ Π²Π°Π·ΠΎΠ΄ΠΈΠ»Π°ΡΡΡΡΠΈΠΉ Π΅ΡΠ΅ΠΊΡ Ρ Π³ΡΡΠΏΡ L-ΠΊΠ°ΡΠ½ΡΡΠΈΠ½Ρ Π· ΠΏΠ°ΡΠ°Π»Π΅Π»ΡΠ½ΠΈΠΌ Π·Π½ΠΈΠΆΠ΅Π½Π½ΡΠΌ ΡΡΠ²Π½Ρ ΠΌΠ°ΡΠΊΠ΅ΡΡΠ² ΡΠΈΡΡΠ΅ΠΌΠ½ΠΎΠ³ΠΎ Π·Π°ΠΏΠ°Π»Π΅Π½Π½Ρ
Micro-fabrication of ceramics : additive manufacturing and conventional technologies
Peer reviewedPublisher PD