Parental Mentalizing during Middle Childhood: How Is the Adoption of a Reflective Stance Associated with Child’s Psychological Outcomes?

This exploratory cross-sectional study attempts to understand the mechanisms underlying the role of parental mentalizing in a child’s psychological functioning during middle childhood by using Parental Reflective Functioning (PRF) and Parental Insightfulness (PI) constructs. The main aims are to examine the role of PI and PRF as processes capable of influencing a child’s psychological functioning in terms of emotional–behavioral difficulties and social–emotional competencies. Eighty-six community parents (48 mothers, 38 fathers) and their 50 children in middle childhood (Mage = 10.10, SD = 1.13) participated in this study, recruited through a non-probabilistic sampling. The following measures were used to assess the aims of this study: Insightfulness Assessment, Parental Reflective Functioning Questionnaire, Child Behavior Check-list (CBCL) and Devereux Student Strengths Assessment (DESSA) questionnaires. Results showed that parental mentalizing was found to be significantly associated with both child’s internalizing and externalizing symptoms and social–emotional competencies as reported by parents through the CBCL and DESSA questionnaires. This study may offer a contribution to the study of parental mentalizing during middle childhood, supporting the hypothesis that both parents’ ability to understand their child’s mental states could affect the child’s psychological functioning. Clinical and theoretical implications are geared toward a family-based view with a specific focus on the importance of fostering in both parents a positive attitude toward mentalizing processes

Unravelling the role of sphingolipids in cystic fibrosis lung disease.

Abstract Cystic fibrosis (CF), one of the most common lethal hereditary diseases of white European populations, is caused by loss-of-function mutations in the CF Transmembrane conductance Regulator (CFTR) gene. One of the main causes of mortality is the onset of CF lung disease, which is characterized by chronic infection and inflammation resulting in the progressive remodelling, irreversible damage and fibrosis of the airways. An increasing number of studies indicate that sphingolipids are crucial players in pulmonary manifestations of CF, even if their direct involvement in CF lung disease is still unclear. In this review, we give an overview of the role of sphingolipids in CF pulmonary disease, focusing on the relationship between glycosphingolipids and lung inflammation, which represents the main hallmark of this disease

Fine needle cytology of complex thyroid nodules.

OBJECTIVE: To evaluate whether a preliminary aspiration (ASP) of the cystic component and/or using spinal needles in complex thyroid nodules (CTN) could improve the adequacy of cytological sampling. METHODS: Between January 2004 and December 2006, 386 consecutive patients with CTN were enrolled in this prospective investigation. Ultrasound (US) fine needle aspiration cytology (FNAC) of the solid component of the nodule (one nodule per patient) was performed using two different 25 gauge needles, with (Yale Spinal, YS) or without (Neolus, NS) a stylet, in alternate sequence on consecutive patients. In addition, a subgroup of patients presenting larger cystic component (approximately 50%) was submitted to total aspiration of the cystic component (ASP+) or not submitted (ASP-) before US-FNAC, in alternate sequence within each needle type group. All the samplings were performed by a single endocrinologist. RESULTS: Adequate specimens were observed in 163 (84.5%) and 183 (94.8%) nodules investigated by NS and YS respectively. Sampling with the stylet needle was associated with an overall significant reduction of non-diagnostic specimens (15.5% vs 5.2% by NS and YS respectively, P < 0.001). The favourable result obtained with YS was independent from preliminary aspiration of the cystic component (ASP+: 14.8% vs 5.7% by NS and YS; ASP-: 16.2% vs 4.8%, not significant). A logistic regression analysis, taking into account nodule size and presence of intranodal vascularity at eco-colour evaluation of the solid component, confirmed that needle type was the only significant predictor of successful sampling (odds ratio 3.6 (95% confidence interval 1.7-7.6), P < 0.001). CONCLUSIONS: Our data show that adopting stylet needles to perform FNAC in CTN may significantly improve the percentage of adequate sampling. On the other hand, preliminary aspiration of CTN with large cystic component does not add any advantage

Hybrid fibroin/polyurethane small-diameter vascular grafts: from fabrication to in vivo preliminary assessment

To address the need of alternatives to autologous vessels for small-calibre vascular applications (e.g. cardiac surgery), a bio-hybrid semi-degradable material composed of silk fibroin (SF) and polyurethane (Silkothane (R)) was herein used to fabricate very small-calibre grafts (o(in) = 1.5 mm) via electrospinning. Bio-hybrid grafts were in vitro characterized in terms of morphology and mechanical behaviour, and compared to similar grafts of pure SF. Similarly, two native vessels from a rodent model (abdominal aorta and vena cava) were harvested and characterized. Preliminary implants were performed on Lewis rats to confirm the suitability of Silkothane (R) grafts for small-calibre applications, specifically as aortic insertion and femoral shunt. The manufacturing process generated pliable grafts consisting of a randomized fibrous mesh and exhibiting similar geometrical features to rat aortas. Both Silkothane (R) and pure SF grafts showed radial compliances in the range from 1.37 +/- 0.86 to 1.88 +/- 1.01% 10(-2) mmHg(-1), lower than that of native vessels. The Silkothane (R) small-calibre devices were also implanted in rats demonstrating to be adequate for vascular applications; all the treated rats survived the surgery for three months after implantation, and 16 rats out of 17 (94%) still showed blood flow inside the graft at sacrifice. The obtained results lay the basis for a deeper investigation of the interaction between the Silkothane (R) graft and the implant site, which may deal with further analysis on the potentialities in terms of degradability and tissue formation, on longer time-points

Political airs : from monitoring to attuned sensing air pollution

In Madrid, as in many European cities, air pollution is known about and made accountable through techno-scientific monitoring processes based on data, and the toxicity of the air is defined through epidemiological studies and made political through policy. In 2009, Madrid’s City Council changed the location of its air quality monitoring stations without notice, reducing the average pollution of the city and therefore provoking a public scandal. This scandal challenged the monitoring process, as the data that used to be the evidence of pollution could not be relied on anymore. To identify the characteristics of some of the diverse forms of public’s participation that emerged, I route theories of environmental sensing from STS and feminist theory through the notion of attuned sensing. Reading environmental sensing through the processual and orientational processes of attunement expands the ways in which toxicity can be sensed outside of quantitative data. This mode of sensing recognizes how the different spontaneous attunements to and with air pollution and the scandal acknowledged Madrid’s chemical infrastructure, rendering visible qualitative conditions of toxicity. This mode of sensing politicized the toxicity of the air not through management or policy making, nor only through established forms environmental activism, but through contagion and accumulation of the different forms of public participation. All together, they made air pollution a matter of public concern. They also redistributed the actors, practices and objects that make the toxicity not only knowable, but also accountable, and most importantly, they opened up spaces for citizen intervention

Utilización de caolín calcinado como puzolana: determinación de la temperatura óptima de calcinación

La utilización de puzolanas como reemplazo parcial del cemento contribuye al aumento de la resistencia y durabilidad de los morteros, a la vez que disminuye el impacto ambiental. El caolín calcinado puede ser utilizado como puzolana. En este trabajo se analizó la utilización de un caolín procedente de La Rioja, Argentina, con el fin de determinar la temperatura óptima a utilizar durante la calcinación del mismo para maximizar su reactividad con Ca(OH)₂, posicionándolo como una buena puzolana. Para esto se realizaron estudios cinéticos que permitieron obtener valores de constantes de velocidad de reacción, los cuales fueron utilizados para seleccionar la mejor temperatura de calcinación, resultando la misma de 700ºC.Centro de Tecnología de Recursos Minerales y Cerámic