8 research outputs found

    Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients

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    Hydrogen gas gap heat switch operating in the 150 K to 400 K temperature range

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    This work was supported by ESA contract 4000114171/15/NL/KM Publisher Copyright: © 2021 Elsevier LtdA prototype of a compact hydrogen gas gap heat switch (GGHS), built using the difference in the linear thermal expansion coefficients of copper and stainless steel, was designed to work in the temperature range of 150 K to 400 K. Using hydrogen, nitrogen and helium as working gas, a gap of 18 µm was measured. With hydrogen, an ON/OFF switching ratio higher than 100 was obtained at 150 K. A sorption pump was integrated to the GGHS and filled with the metal hydride ZrMn2 to overcome the very low adsorption of hydrogen with activated carbon, material frequently used to manage the pressure in the gap. This solution allowed to reach both ON and OFF states by varying its temperature between 150 K and 300 K. The results obtained suggest that the proposed design allows for the development of tunable hydrogen heat switches while keeping the assembly very simple and sturdy.authorsversionpublishe

    Low versus standard calorie and protein feeding in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group trial (NUTRIREA-3)

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    Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients

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    International audienceThe aim of this study was to estimate the incidence of COVID-19 disease in the French national population of dialysis patients, their course of illness and to identify the risk factors associated with mortality. Our study included all patients on dialysis recorded in the French REIN Registry in April 2020. Clinical characteristics at last follow-up and the evolution of COVID-19 illness severity over time were recorded for diagnosed cases (either suspicious clinical symptoms, characteristic signs on the chest scan or a positive reverse transcription polymerase chain reaction) for SARS-CoV-2. A total of 1,621 infected patients were reported on the REIN registry from March 16th, 2020 to May 4th, 2020. Of these, 344 died. The prevalence of COVID-19 patients varied from less than 1% to 10% between regions. The probability of being a case was higher in males, patients with diabetes, those in need of assistance for transfer or treated at a self-care unit. Dialysis at home was associated with a lower probability of being infected as was being a smoker, a former smoker, having an active malignancy, or peripheral vascular disease. Mortality in diagnosed cases (21%) was associated with the same causes as in the general population. Higher age, hypoalbuminemia and the presence of an ischemic heart disease were statistically independently associated with a higher risk of death. Being treated at a selfcare unit was associated with a lower risk. Thus, our study showed a relatively low frequency of COVID-19 among dialysis patients contrary to what might have been assumed

    Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients

    No full text
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