827 research outputs found
A Research Based District Wide Discpline Policy, from Goal to Approval
In the late 1990\u27s the Wenatchee School District realized that the community and staff were dissatisfied with the state of discipline in the district. The schools, as is the case in the community at large, could no longer rely on traditional approaches to dealing with a growing number of incidents of anti-social behavior. A lack of discipline appeared to be at the root of the problem in the home and subordinately the root of the problem in the schools (McEvoy & Welker, 2000). In addition, disciplinary practices in many schools are inconsistent and ineitable (Skiba & Peterson, 2000). The District Discipline Policy Task Force was formed to develop a new research based district-wide policy that would address this problem plaguing our schools. This author, as a member of the task force, did extensive reading leading up to the meetings held on the policy. Books, professional journals, packaged plans, existing programs, and existing policies were studied for examples that could be adapted for use by the Wenatchee School District. The data collected was synthesized into the new research based discipline policy via the committee process. This project takes the reader through the process, from initial research to the finished, and approved, policy
The Presence of COPD does not Influence Clinical Outcomes in Hospitalized Patients with Community-acquired Pneumonia
Introduction
Community-acquired pneumonia (CAP) is a leading cause of death worldwide. Chronic obstructive pulmonary disease (COPD) is a well-established risk factor for development of CAP. What is not as clear is the impact of COPD in the outcomes of patients with CAP. In this study, we compared the outcomes of CAP in COPD and non-COPD patients.
Methods
This was a retrospective cohort study. We conducted a secondary analysis of the Community-Acquired Pneumonia Organization (CAPO) international cohort study database, which includes patients with CAP admitted to several hospitals throughout the world. Outcomes were time to clinical stability, length of hospital stay, and in-hospital mortality.
Results
This study included 7,325 patients. Of these, 1,869 (25.5%) had COPD. Patients with COPD had higher severity of illness (pneumonia severity index class V: 15% vs 9%; P
Conclusion
Our study results show that COPD should not be considered a risk factor for poor outcomes in hospitalized patients with CAP
Lung Cytokines and Systemic Inflammation in Patients with COPD
Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by lung and systemic inflammation. The role of cytokines in local and systemic inflammation in COPD is not well understood. This study aimed to compare plasma and bronchoalveolar lavage (BAL) fluid cytokine levels in COPD and non-COPD subjects with the intent of better understand their potential roles in driving local and systemic inflammation.
Methods: This cross-sectional study analyzed data from 65 subjects: 31 with COPD confirmed by spirometry and 34 non-COPD controls. All subjects underwent spirometry, plasma sample collection, and bronchoscopy/BAL. Levels of 21 inflammatory cytokines were measured in the plasma (systemic inflammation) and BAL (lung inflammation) using a multiplex assay.
Results:COPD subjects were overall older (median age 59 vs 36; p =
Conclusion: Elevated levels of cytokines were identified in the plasma of COPD subjects when compared to controls, supporting the role of these mediators as one of the mechanisms of systemic inflammation in COPD. In contrast, lung cytokines were not elevated suggesting that inflammation in the setting of COPD may not originate and/or perpetuate in the lungs, or that the BAL fluid is not an optimal source of information when evaluating inflammation in COPD. Although the role of these cytokines remains uncertain, anti-cytokine therapy might modulate inflammation in COPD and perhaps improve outcomes
Precision tomography of a three-qubit electron-nuclear quantum processor in silicon
Nuclear spins were among the first physical platforms to be considered for
quantum information processing, because of their exceptional quantum coherence
and atomic-scale footprint. However, their full potential for quantum computing
has not yet been realized, due to the lack of methods to link nuclear qubits
within a scalable device combined with multi-qubit operations with sufficient
fidelity to sustain fault-tolerant quantum computation. Here we demonstrate
universal quantum logic operations using a pair of ion-implanted P
nuclei in a silicon nanoelectronic device. A nuclear two-qubit controlled-Z
gate is obtained by imparting a geometric phase to a shared electron spin, and
used to prepare entangled Bell states with fidelities up to 94.2(2.7)%. The
quantum operations are precisely characterised using gate set tomography (GST),
yielding one-qubit gate fidelities up to 99.93(3)%, two-qubit gate fidelity of
99.21(14)% and two-qubit preparation/measurement fidelities of 98.95(4)%. These
three metrics indicate that nuclear spins in silicon are approaching the
performance demanded in fault-tolerant quantum processors. We then demonstrate
entanglement between the two nuclei and the shared electron by producing a
Greenberger-Horne-Zeilinger three-qubit state with 92.5(1.0)% fidelity. Since
electron spin qubits in semiconductors can be further coupled to other
electrons or physically shuttled across different locations, these results
establish a viable route for scalable quantum information processing using
nuclear spins.Comment: 27 pages, 14 figures, plus 20 pages supplementary information. v2
includes new and updated references, and minor text change
Les droits disciplinaires des fonctions publiques : « unification », « harmonisation » ou « distanciation ». A propos de la loi du 26 avril 2016 relative à la déontologie et aux droits et obligations des fonctionnaires
The production of tt⟠, W+bb⟠and W+cc⟠is studied in the forward region of protonâproton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98±0.02 fbâ1 . The W bosons are reconstructed in the decays WââÎœ , where â denotes muon or electron, while the b and c quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions.The production of , and is studied in the forward region of proton-proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98 0.02 \mbox{fb}^{-1}. The bosons are reconstructed in the decays , where denotes muon or electron, while the and quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions
Study of the decay
The decay is studied
in proton-proton collisions at a center-of-mass energy of TeV
using data corresponding to an integrated luminosity of 5
collected by the LHCb experiment. In the system, the
state observed at the BaBar and Belle experiments is
resolved into two narrower states, and ,
whose masses and widths are measured to be where the first uncertainties are statistical and the second
systematic. The results are consistent with a previous LHCb measurement using a
prompt sample. Evidence of a new
state is found with a local significance of , whose mass and width
are measured to be and , respectively. In addition, evidence of a new decay mode
is found with a significance of
. The relative branching fraction of with respect to the
decay is measured to be , where the first
uncertainty is statistical, the second systematic and the third originates from
the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb
public pages
Measurement of CP violation parameters and polarisation fractions in decays
The first measurement of asymmetries in the decay and an updated measurement of its branching fraction and polarisation fractions are presented. The results are obtained using data corresponding to an integrated luminosity of of proton-proton collisions recorded with the LHCb detector at centre-of-mass energies of and . Together with constraints from , the results are used to constrain additional contributions due to penguin diagrams in the -violating phase , measured through decays to charmonium.The first measurement of CP asymmetries in the decay and an updated measurement of its branching fraction and polarisation fractions are presented. The results are obtained using data corresponding to an integrated luminosity of 3.0 fb^{â}^{1} of proton-proton collisions recorded with the LHCb detector at centre-of-mass energies of 7 and 8 TeV. Together with constraints from B â J/Ï Ï, the results are used to constrain additional contributions due to penguin diagrams in the CP -violating phase Ï , measured through B decays to charmonium.The first measurement of asymmetries in the decay and an updated measurement of its branching fraction and polarisation fractions are presented. The results are obtained using data corresponding to an integrated luminosity of of proton-proton collisions recorded with the LHCb detector at centre-of-mass energies of and . Together with constraints from , the results are used to constrain additional contributions due to penguin diagrams in the -violating phase , measured through decays to charmonium
Measurement of the J/Ï pair production cross-section in pp collisions at TeV
The production cross-section of J/Ï pairs is measured using a data sample of pp collisions collected by the LHCb experiment at a centre-of-mass energy of TeV, corresponding to an integrated luminosity of 279 ±11 pb. The measurement is performed for J/Ï mesons with a transverse momentum of less than 10 GeV/c in the rapidity range 2.0 < y < 4.5. The production cross-section is measured to be 15.2 ± 1.0 ± 0.9 nb. The first uncertainty is statistical, and the second is systematic. The differential cross-sections as functions of several kinematic variables of the J/Ï pair are measured and compared to theoretical predictions.The production cross-section of pairs is measured using a data sample of collisions collected by the LHCb experiment at a centre-of-mass energy of , corresponding to an integrated luminosity of . The measurement is performed for mesons with a transverse momentum of less than in the rapidity range . The production cross-section is measured to be . The first uncertainty is statistical, and the second is systematic. The differential cross-sections as functions of several kinematic variables of the pair are measured and compared to theoretical predictions
Measurement of forward production in collisions at TeV
A measurement of the cross-section for production in collisions is presented using data corresponding to an integrated luminosity of fb collected by the LHCb experiment at a centre-of-mass energy of TeV. The electrons are required to have more than GeV of transverse momentum and to lie between 2.00 and 4.25 in pseudorapidity. The inclusive production cross-sections, where the decays to , are measured to be \begin{align*} \begin{split} \sigma_{W^{+} \to e^{+}\nu_{e}}&=1124.4\pm 2.1\pm 21.5\pm 11.2\pm 13.0\,\mathrm{pb},\\ \sigma_{W^{-} \to e^{-}\bar{\nu}_{e}}&=\,\,\,809.0\pm 1.9\pm 18.1\pm\,\,\,7.0\pm \phantom{0}9.4\,\mathrm{pb}, \end{split} \end{align*} where the first uncertainties are statistical, the second are systematic, the third are due to the knowledge of the LHC beam energy and the fourth are due to the luminosity determination. Differential cross-sections as a function of the electron pseudorapidity are measured. The cross-section ratio and production charge asymmetry are also reported. Results are compared with theoretical predictions at next-to-next-to-leading order in perturbative quantum chromodynamics. Finally, in a precise test of lepton universality, the ratio of boson branching fractions is determined to be \begin{align*} \begin{split} \mathcal{B}(W \to e\nu)/\mathcal{B}(W \to \mu\nu)=1.020\pm 0.002\pm 0.019, \end{split} \end{align*} where the first uncertainty is statistical and the second is systematic.A measurement of the cross-section for production in collisions is presented using data corresponding to an integrated luminosity of fb collected by the LHCb experiment at a centre-of-mass energy of TeV. The electrons are required to have more than GeV of transverse momentum and to lie between 2.00 and 4.25 in pseudorapidity. The inclusive production cross-sections, where the decays to , are measured to be \begin{equation*} \sigma_{W^{+} \to e^{+}\nu_{e}}=1124.4\pm 2.1\pm 21.5\pm 11.2\pm 13.0\,\mathrm{pb}, \end{equation*} \begin{equation*} \sigma_{W^{-} \to e^{-}\bar{\nu}_{e}}=\,\,\,809.0\pm 1.9\pm 18.1\pm\,\,\,7.0\pm \phantom{0}9.4\,\mathrm{pb}, \end{equation*} where the first uncertainties are statistical, the second are systematic, the third are due to the knowledge of the LHC beam energy and the fourth are due to the luminosity determination. Differential cross-sections as a function of the electron pseudorapidity are measured. The cross-section ratio and production charge asymmetry are also reported. Results are compared with theoretical predictions at next-to-next-to-leading order in perturbative quantum chromodynamics. Finally, in a precise test of lepton universality, the ratio of boson branching fractions is determined to be \begin{equation*} \mathcal{B}(W \to e\nu)/\mathcal{B}(W \to \mu\nu)=1.020\pm 0.002\pm 0.019, \end{equation*} where the first uncertainty is statistical and the second is systematic.A measurement of the cross-section for W â eÎœ production in pp collisions is presented using data corresponding to an integrated luminosity of 2 fb collected by the LHCb experiment at a centre-of-mass energy of TeV. The electrons are required to have more than 20 GeV of transverse momentum and to lie between 2.00 and 4.25 in pseudorapidity. The inclusive W production cross-sections, where the W decays to eÎœ, are measured to be where the first uncertainties are statistical, the second are systematic, the third are due to the knowledge of the LHC beam energy and the fourth are due to the luminosity determination
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