21 research outputs found

    Nano-scale reservoir computing

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    This work describes preliminary steps towards nano-scale reservoir computing using quantum dots. Our research has focused on the development of an accumulator-based sensing system that reacts to changes in the environment, as well as the development of a software simulation. The investigated systems generate nonlinear responses to inputs that make them suitable for a physical implementation of a neural network. This development will enable miniaturisation of the neurons to the molecular level, leading to a range of applications including monitoring of changes in materials or structures. The system is based around the optical properties of quantum dots. The paper will report on experimental work on systems using Cadmium Selenide (CdSe) quantum dots and on the various methods to render the systems sensitive to pH, redox potential or specific ion concentration. Once the quantum dot-based systems are rendered sensitive to these triggers they can provide a distributed array that can monitor and transmit information on changes within the material.Comment: 8 pages, 9 figures, accepted for publication in Nano Communication Networks, http://www.journals.elsevier.com/nano-communication-networks/. An earlier version was presented at the 3rd IEEE International Workshop on Molecular and Nanoscale Communications (IEEE MoNaCom 2013

    Implication of a novel multiprotein Dam1p complex in outer kinetochore function

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    Dam1p, Duo1p, and Dad1p can associate with each other physically and are required for both spindle integrity and kinetochore function in budding yeast. Here, we present our purification from yeast extracts of an ∼245 kD complex containing Dam1p, Duo1p, and Dad1p and Spc19p, Spc34p, and the previously uncharacterized proteins Dad2p and Ask1p. This Dam1p complex appears to be regulated through the phosphorylation of multiple subunits with at least one phosphorylation event changing during the cell cycle. We also find that purified Dam1p complex binds directly to microtubules in vitro with an affinity of ∼0.5 μM. To demonstrate that subunits of the Dam1p complex are functionally important for mitosis in vivo, we localized Spc19–green fluorescent protein (GFP), Spc34-GFP, Dad2-GFP, and Ask1-GFP to the mitotic spindle and to kinetochores and generated temperature-sensitive mutants of DAD2 and ASK1. These and other analyses implicate the four newly identified subunits and the Dam1p complex as a whole in outer kinetochore function where they are well positioned to facilitate the association of chromosomes with spindle microtubules

    Managing Extreme Heat and Smoke: A Focus Group Study of Vulnerable People in Darwin, Australia

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    Extreme heat and poor air quality arising from landscape fires are an increasing global concern driven by anthropogenic climate change. Previous studies have shown these environmental conditions are associated with negative health outcomes for vulnerable people. Managing and adapting to these conditions in a warming climate can present substantial difficulties, especially in climates already challenging for human habitation. This study was set in the tropical city of Darwin, Australia. We recruited individuals from population groups vulnerable to outdoor hazards: outdoor workers, teachers and carers, and sportspeople, to participate in focus group discussions. We aimed to gain an understanding of the impacts of extreme heat and poor air quality and how individuals perceived and managed these environmental conditions. We identified a number of key themes relating to impacts on health, work and activity, and adaptive behaviors, while identifying gaps in policy and infrastructure that could improve the lives and protect the health of vulnerable people living, working, and playing in this region. In addition, these outcomes potentially provide direction for other regions with similar environmental challenges. Extreme heat and poor air quality place an additional burden on the lives of people in high-risk settings, such as outdoor workers, teachers and carers, and sportspeople

    Electrochemically-assisted ammonia recovery from wastewater using a floating electrode

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    This work presents and explores a novel methodology for the removal and recovery of ammonia from wastewater based upon two mechanisms: electrochemical oxidation and a previously unreported electrochemically-assisted surface transfer mechanism. Recovery of ammonia is enabled by placing a porous cathodic electrode at the wastewater-air interface. In this configuration, the cathode creates local alkalinity and an electric field that draws ammonium ions towards the wastewater-air interface, resulting in near-linear reductions of dissolved ammonium irrespective of concentration. This approach leads to significant ammonia recovery without the need for ion-exchange membranes. In addition, anodic reactions that simultaneously occur at depth in the wastewater induce ammonia oxidation in accordance with proven mechanisms. The floating electrode approach offers improved ammonia removal efficiency in comparison to electrooxidation. Trials conducted on synthetic wastewater (900 mg NH4+-N l−1) and filtered anaerobic centrate (560 mg NH4+-N l−1) demonstrated ammonia concentration decreases up to 216 mg l−1 hr−1 and 110 mg l−1 hr−1, respectively, under the application of 5 mA cm−2 current density. The technology would be best used to treat municipal and industrial wastewaters possessing high ammonia concentration, including anaerobic digester centrate and urine, and offers potential to assist in removing ammonia from environmental waters.</jats:p

    Environmental Life Cycle Costing and Sustainability: Insights from Pollution Abatement and Resource Recovery in Wastewater Treatment

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    The relationship between environmental life cycle costing (ELCC) and sustainability was explored using two detailed wastewater case studies. The case studies were selected to increase the tension between existing market values and values for sustainability; the first case study considered incremental change to an existing plant and the second considered a paradigm shift in wastewater treatment. Pollution control provided the greatest cost savings for the first case study and provided a "win-win" result-meeting existing standards and saving money. However, benefits for pollution control beyond current standards were not captured, which emphasized the role of standards to internalize as well as limit the values considered in ELCC. In the second case study, the value of water had the potential to change the focus of wastewater design from pollution abatement to resource recovery. However, social acceptance of recovered water and market access for resources created large risk for investment. The ELCC was also sensitive to the discount rate which limited longer-term considerations. Other sustainability values such as scarcity and ecological thresholds were not captured. The ELCC code of practice suggests including such costs if likely in the foreseeable future; defining these values may also clarify the role of ELCC to evaluate sustainability over the life cycle

    Wastewater – an untapped resource?

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    These pressures require the water industry to develop innovative and more efficient processes to optimise resource recovery from wastewater, according to a new report by the Academy of Technology and Engineering (ATSE). &nbsp; The report notes that Australian wastewater contains nutrients, carbon, energy and other inorganic and organic resources worthy of recovery and examines the potential industry opportunities for resource recovery in Australia. &nbsp; It reviews international case studies, considers the Australian regulatory framework and evaluates the key technologies and products, as well as analysing several investment options. The report shows that there are several significant value-creating opportunities to pursue for investors in Australia in the medium term. &nbsp; Wastewater – An Untapped Resource? was prepared by ATSE with funding from the Australian Water Recycling Centre of Excellence. &nbsp; The report was developed by a working group led by Dr John Burgess FTSE, a chemical engineer who has more than 20 years’ experience as a senior executive and research leader. It included Professor Damien Batstone, Deputy Director of the Advanced Water Management Centre at the University of Queensland, Dr Tim Muster, a Senior Research Scientist from CSIRO Land and Water, and Mr Francis Pamminger, Manager of Research and Innovation at Yarra Valley Water. &nbsp

    Designing green, self-healing coatings for metal protection

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    Omics-based approaches and their use in the assessment of microbial-influenced corrosion of metals

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    Microbial-influenced corrosion (MIC) has been known to have economic, environmental, and social implications to offshore oil and gas pipelines, concrete structures, and piped water assets. While corrosion itself is a relatively simple process, the localised manner of corrosion makes in situ assessments difficult. Furthermore, corrosion assessments tend to be measured as part of a forensic investigation. Compounding the issue further is the impact of microbiological/biofilm processes, where corrosion is influenced by the complex processes of different microorganisms performing different electrochemical reactions and secreting proteins and metabolites that can have secondary effects. While traditional microbiological culture-dependent techniques and electrochemical/physical assessments provide some insight into corrosion activity, the identity and role of microbial communities that are related to corrosion and corrosion inhibition in different materials and in different environments are scarce. One avenue to explore MIC and MIC inhibition is through the application of omics-based techniques, where insight into the bacterial population in terms of diversification and their metabolism can be further understood. As such, this paper discusses the recent progresses made in a number of fields that have used omics-based applications to improve the fundamental understanding of biofilms and MIC processes
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