207 research outputs found

    Applying Big Data Technology to University Libraries: A Perspective Based on Service Context

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    In the era of big data, the construction of university libraries cannot be separated from the support of big data technology. The collection and analysis of data can improve the management efficiency and service quality of university libraries. On the basis of explaining the characteristics of big data and big data related technologies, our study puts forward the application framework of big data technology in university libraries based on the characteristics of university libraries. Based on the perspective of the context, we explore the effects of the application form of big data technology in university libraries on students \u27perception of the context, and establish a theoretical model of how it will affect students\u27 perceived service quality, perceived value and satisfaction the library. Our research can give suggestions to the service innovation practice of university libraries

    Two Solar Tornadoes Observed with the Interface Region Imaging Spectrograph

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    The barbs or legs of some prominences show an apparent motion of rotation, which are often termed solar tornadoes. It is under debate whether the apparent motion is a real rotating motion, or caused by oscillations or counter-streaming flows. We present analysis results from spectroscopic observations of two tornadoes by the Interface Region Imaging Spectrograph. Each tornado was observed for more than 2.5 hours. Doppler velocities are derived through a single Gaussian fit to the Mg~{\sc{ii}}~k~2796\AA{}~and Si~{\sc{iv}}~1393\AA{}~line profiles. We find coherent and stable red and blue shifts adjacent to each other across the tornado axes, which appears to favor the interpretation of these tornadoes as rotating cool plasmas with temperatures of 10410^4 K-10510^5 K. This interpretation is further supported by simultaneous observations of the Atmospheric Imaging Assembly on board the Solar Dynamics Observatory, which reveal periodic motions of dark structures in the tornadoes. Our results demonstrate that spectroscopic observations can provide key information to disentangle different physical processes in solar prominences.Comment: 14 figures, accepted by Ap

    Dark structures in sunspot light bridges

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    We present unprecedented high-resolution TiO images and Fe I 1565 nm spectropolarimetric data of two light bridges taken by the 1.6-m Goode Solar Telescope at Big Bear Solar Observatory. In the first light bridge (LB1), we find striking knot-like dark structures within the central dark lane. Many dark knots show migration away from the penumbra along the light bridge. The sizes, intensity depressions and apparent speeds of their proper motion along the light bridges of 33 dark knots identified from the TiO images are mainly in the ranges of 80∼\sim200~km, 30\%∼\sim50\%, and 0.3∼\sim1.2~km~s−1^{-1}, respectively. In the second light bridge (LB2), a faint central dark lane and striking transverse intergranular lanes were observed. These intergranular lanes have sizes and intensity depressions comparable to those of the dark knots in LB1, and also migrate away from the penumbra at similar speeds. Our observations reveal that LB2 is made up of a chain of evolving convection cells, as indicated by patches of blue shift surrounded by narrow lanes of red shift. The central dark lane generally corresponds to blueshifts, supporting the previous suggestion of central dark lanes being the top parts of convection upflows. In contrast, the intergranular lanes are associated with redshifts and located at two sides of each convection cell. The magnetic fields are stronger in intergranular lanes than in the central dark lane. These results suggest that these intergranular lanes are manifestations of convergent convective downflows in the light bridge. We also provide evidence that the dark knots observed in LB1 may have a similar origin.Comment: 6 figure

    Interdisciplinary Systemic Innovation for Healing and Creating Resilient Communities in the Post-COVID-19 era

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    The functioning mechanisms of society are encountered with enormous unexpected extreme problems and unanticipated butterfly effects, which are confronted with increasingly complex global challenges and faced with increasingly uncertain futures. The whole world operating system has been deeply influenced by the widespread COVID-19 pandemic and the ensuing economic, social, and cultural catastrophes, and many individuals have suffered severe psychological pressure. Therefore, exploring systemic innovation to heal residents’ emotions, build resilient communities, and foster economic recovery and socially inclusive sustainable development is of great urgent and relevant importance in the post-COVID-19 period, which is challenging to be addressed by an isolated discipline or field. Therefore, this research will attempt to cooperate with uncertainty to reveal the potential for systemic innovation through a multidisciplinary analysis and research. This research first presents three groups of stakeholders: the general public, vulnerable groups, and healthcare employees, to illustrate the systemic psychological burden of the COVID-19 pandemic on various communities. Then, a multidisciplinary analysis containing psychology, medicine, sociology, and design was conducted to clarify the current approaches, practical impediments, and potential for system evolution. Finally, this research selects Chifeng Road as an experimental intervention location through a design thinking-oriented interdisciplinary systemic innovation. It then presents an emotional healing system that integrates multidisciplinary perspectives and knowledge to reduce the surrounding residents’ psychological stress. And fosters a resilient community that can adapt more quickly to post-pandemic life, while also carrying the potential for future innovation in social systems

    Structured Sparsity Learning for Efficient Video Super-Resolution

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    The high computational costs of video super-resolution (VSR) models hinder their deployment on resource-limited devices, (e.g., smartphones and drones). Existing VSR models contain considerable redundant filters, which drag down the inference efficiency. To prune these unimportant filters, we develop a structured pruning scheme called Structured Sparsity Learning (SSL) according to the properties of VSR. In SSL, we design pruning schemes for several key components in VSR models, including residual blocks, recurrent networks, and upsampling networks. Specifically, we develop a Residual Sparsity Connection (RSC) scheme for residual blocks of recurrent networks to liberate pruning restrictions and preserve the restoration information. For upsampling networks, we design a pixel-shuffle pruning scheme to guarantee the accuracy of feature channel-space conversion. In addition, we observe that pruning error would be amplified as the hidden states propagate along with recurrent networks. To alleviate the issue, we design Temporal Finetuning (TF). Extensive experiments show that SSL can significantly outperform recent methods quantitatively and qualitatively. We will release codes and models

    Deciphering the role of HPV-mediated metabolic regulation in shaping the tumor microenvironment and its implications for immunotherapy in HNSCC

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    Head and neck squamous cell carcinoma (HNSCC), as a complex and variable malignancy, poses a significant threat to human health. Since the intricate association between HPV and HNSCC emerged, its role within the TME has garnered extensive attention. HPV+HNSCC exhibits distinct immunological characteristics within the TME, intricately intertwined with mechanisms of immune evasion. HPV employs multifaceted pathways to intervene in metabolic regulation within the TME, exerting influence over immune cell functionality and neoplastic cell genesis. Furthermore, the heightened immune reactivity exhibited by HPV+HNSCC within the TME augments responses to immune interventions such as immune checkpoint inhibitors. Therefore, amidst the current limitations of therapeutic approaches, immunotherapy stands as a promising strategy to overcome the conventional confines of treating HNSCC. This article comprehensively outlines the impact of HPV on the inception and progression of HNSCC while discussing the amalgamation of metabolic regulation within the TME and immunotherapeutic strategies. By intervening in the reciprocal interactions between HPV and HNSCC within the TME, the potential to modulate the efficacy of immune-based treatments becomes evident. Concurrently, a synthesis of pertinent biomarker development is summarized. Such endeavors hold paramount significance for personalized therapeutic approaches and the more effective management of HNSCC patients

    Nature-derived epigallocatechin gallate/duck’s feet collagen/hydroxyapatite composite sponges for enhanced bone tissue regeneration

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    Scaffolds mimicking structural and chemical characteristics of the native bone tissues are critical for bone tissue engineering. Herein, we have developed and characterized epigallocatechin gallate/duck's feet collagen/hydroxyapatite (EGCG/DC/HAp) composite sponges that enhanced the bone tissue regeneration. The three-dimensional composite sponges were synthesized by loading various amounts (i.e. 1, 5 and 10 μM) of EGCG to duck feet derived collagen followed by freeze-drying and then coating with hydroxyapatite. Several measuremental techniques were employed to examine the properties of the as-fabricated composite sponges including morphology and structure, porosity, compressive strength, etc. and as well compared with pristine duck feet derived collagen. SEM observations of EGCG/DC/HAp sponges showed the formation of a highly porous collagen matrix with EGCG embodiment. The porosity and pore size of sponges were found to increase by high EGCG content. The compressive strength was calculated as 3.54 ± 0.04, 3.63 ± 0.03, 3.89 ± 0.05, 4.047 ± 0.05 MPa for 1, 5 and 10 μM EGCG/DC/HAp sponges, respectively. Osteoblast-like cell (BMSCs isolated from rabbit) culture and in vivo experiments with EGCG/DC/HAp sponges implanted in nude mouse followed by histological staining showed enhanced cell internalization and attachment, cell proliferation, alkaline phosphatase expressions, indicating that EGCG/DC/HAp sponges have ahigh biocompatibility. Moreover, highEGCG content in the EGCG/DC/HAp sponges have led to increased cellular behavior. Collectively, the 5 μM of EGCG/DC/HAp sponges were suggested as the potential candidates for bone tissue regeneration.This research was supported by Technology Commercialization Support Program [grant number 814005-03-3-HD020], MIFAFF; and Basic Science Research Program [grant number NRF2017R1A2B3010270] through the National Research Foundation of Korea, Ministry of Science, ICT and Future Planning, Republic of Korea.info:eu-repo/semantics/publishedVersio

    Translation, adaptation, and initial evaluation of a guided self-help intervention to reduce psychological distress among nurses during COVID-19 in China

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    BackgroundThis study aimed to reduce the unprecedented and intense psychological distress that nurses were forced to experience during the COVID-19 pandemic. A Chinese version of the World Health Organization's Self-Help Plus (SH+) intervention guide was adapted and tested among nurses. The objective of this study was to translate and adapt the SH+ guideline into the Chinese version and to test its feasibility in reducing psychological distress among nurses during COVID-19.MethodsA staged approach comprising translation, adaptations, initial evaluation by pilot implementation, and a qualitative process evaluation was conducted in two hospitals in Xi'an, China. The translation of the Chinese version was authorized by the World Health Organization. We adapted SH+ for use among clinical nurses working during the pandemic in China through a qualitative process evaluation, which was guided by the descriptive phenomenological study design. The outcomes of the pilot included psychological distress, psychological flexibility, depressive and anxiety symptoms, post-traumatic stress disorder (PTSD) symptoms, and subjective psychological wellbeing, which were assessed using the Kessler 6 symptom checklist, the Comprehensive Assessment of ACT Process (CompACT), the Patient Health Questionnaire-9 (PHQ-9), the Generalized Anxiety Disorder scale (GAD-7), the PTSD Checklist-Civilian Version (PCL-C), and the Index of Wellbeing (IWB), respectively.ResultsThe SH+ materials, including audio-recorded sessions and an accompanying illustrated manual, were translated into Chinese and adapted in line with feedback from the nurses. An uncontrolled pilot study (n = 28) for 5 weeks showed a statistically significant reduction of psychological distress (mean difference in Kessler 6 score, −2.74; 95% CI [−3.71, −1.78]; p < 0.001). We also found improvements in psychological flexibility (mean difference in CompACT score, 6.89; 95% CI [−12.35, −4.47]; p < 0.001), subjective psychological wellbeing (mean difference in IWB score, 0.86; 95% CI [0.07, 1.65]; p < 0.05), and depressive symptoms (mean difference in PHQ-9 score, −1.52; 95% CI [−2.78, −0.26]; p < 0.05). The process evaluation showed that nurses found the SH+ program very useful but difficult to adhere to.ConclusionWe found that the translated Chinese version of SH+ was applicable and feasible in the Chinese cultural context. There was a potential effect of adapted SH + in reducing nurses' psychological distress during COVID-19 and suggested the value of exploring strategies to increase adherence to the program

    Allylic oxidation of olefins with a manganese-based metal-organic framework

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    Selective oxidation of olefins to α,β-unsaturated ketones under mild reaction conditions have attracted considerable interest, since α,β-unsaturated ketones can serve to be synthetic precursors for various downstream chemical products. The major challenges inherently with this chemical oxidation are chem-, regio-selectivity as well as environmental concerns, i.e. catalyst recycle, safety and cost. Using atmospheric oxygen as an environmental friendly oxidant, we found that a metal-organic framework (MOF) constructed with Mn and tetrazolate ligand (CPF-5) showed good activity and selectivity for the allylic oxidation of olefins to α,β-unsaturated ketones. Under the optimized condition, we could achieve 98% conversion of cyclohexene and 87% selectivity toward cyclohexanone. The combination of a substoichiometric amount of TBHP (tert-butylhydroperoxide) and oxygen not only provides a cost effective oxidation system but significantly enhances the selectivity to α,β-unsaturated ketones, outperforming most reported oxidation methods. This catalytic system is heterogeneous in nature, and CPF-5 could be reused at least five times without a significant decrease in its catalytic activity and selectivity
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