Understanding the welfare requirements of a neurologically and physically divergent captive male Sumatran orangutan (Pongo abelii)

BackgroundUnderstanding the needs of animals with physical and cognitive impairments is essential for zoos, rehabilitation centres, and other captive contexts. This case study describes the atypical physical and cognitive development of Jiwa, an adult male Sumatran orangutan (Pongo abelii), to evaluate how these differences may impact Jiwa and to explore how cognitive enrichment can be tailored to his skill level.MethodsKeeper records from Jiwa’s birth (1999) to February 2022 were scrutinised to identify key developmental milestones, changes in body weight, and deciduous dental emergence. These were compared with expected milestones for wild and captive orangutans. In addition, a probe feeder apparatus was gradually tailored to an appropriate skill level between January and March 2022.ResultsMany of Jiwa’s developmental milestones were consistent with expected orangutan development, although there were noticeable differences in body weight, dental emergence, locomotion, and cognition. The welfare domains most likely to be negatively impacted by these differences were physical health, expression of agency, and mental wellbeing. After the enrichment device was tailored to an appropriate level of challenge, Jiwa showed marked improvement in engagement and ability to use the device.ConclusionsThis study helps to inform future case studies of atypical great apes by detailing the physical and cognitive development of an individual orangutan. Although Jiwa’s differences may impact his own wellbeing in some areas, he has largely been able to overcome them. However, this case study highlights the challenges involved in tailoring enrichment apparatuses and resilience interventions for atypical individuals

Bipedalism or bipedalisms: The os coxae of StW 573

There has been a long debate about the possibility of multiple contemporaneous species of Australopithecus in both eastern and southern Africa, potentially exhibiting different forms of bipedal locomotion. Here, we describe the previously unreported morphology of the os coxae in the 3.67 Ma Australopithecus prometheus StW 573 from Sterkfontein Member 2, comparing it with variation in ossa coxae in living humans and apes as well as other Plio‐Pleistocene hominins. Statistical comparisons indicate that StW 573 and 431 resemble humans in their anteroposteriorly great iliac crest breadth compared with many other early australopiths, whereas Homo ergaster KNM WT 15000 surprisingly also has a relatively anterioposteriorly short iliac crest. StW 573 and StW 431 appear to resemble humans in having a long ischium compared with Sts 14 and KNM WT 15000. A Quadratic Discriminant Function Analysis of morphology compared with other Plio‐Pleistocene hominins and a dataset of modern humans and hominoids shows that, while Lovejoy's heuristic model of the Ardipithecus ramidus os coxae falls with Pongo or in an indeterminate group, StW 573 and StW 431 from Sterkfontein Member 4 are consistently classified together with modern humans. Although clearly exhibiting the classic “basin shaped” bipedal pelvis, Sts 14 (also from Sterkfontein), AL 288‐1 Australopithecus afarensis, MH2 Australopithecus sediba and KNM‐WT 15000 occupy a position more peripheral to modern humans, and in some analyses are assigned to an indeterminate outlying group. Our findings strongly support the existence of two species of Australopithecus at Sterkfontein and the variation we observe in os coxae morphology in early hominins is also likely to reflect multiple forms of bipedality

Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study

Introduction: The multiorgan impact of moderate to severe coronavirus infections in the post-acute phase is still poorly understood. We aimed to evaluate the excess burden of multiorgan abnormalities after hospitalisation with COVID-19, evaluate their determinants, and explore associations with patient-related outcome measures. Methods: In a prospective, UK-wide, multicentre MRI follow-up study (C-MORE), adults (aged ≥18 years) discharged from hospital following COVID-19 who were included in Tier 2 of the Post-hospitalisation COVID-19 study (PHOSP-COVID) and contemporary controls with no evidence of previous COVID-19 (SARS-CoV-2 nucleocapsid antibody negative) underwent multiorgan MRI (lungs, heart, brain, liver, and kidneys) with quantitative and qualitative assessment of images and clinical adjudication when relevant. Individuals with end-stage renal failure or contraindications to MRI were excluded. Participants also underwent detailed recording of symptoms, and physiological and biochemical tests. The primary outcome was the excess burden of multiorgan abnormalities (two or more organs) relative to controls, with further adjustments for potential confounders. The C-MORE study is ongoing and is registered with ClinicalTrials.gov, NCT04510025. Findings: Of 2710 participants in Tier 2 of PHOSP-COVID, 531 were recruited across 13 UK-wide C-MORE sites. After exclusions, 259 C-MORE patients (mean age 57 years [SD 12]; 158 [61%] male and 101 [39%] female) who were discharged from hospital with PCR-confirmed or clinically diagnosed COVID-19 between March 1, 2020, and Nov 1, 2021, and 52 non-COVID-19 controls from the community (mean age 49 years [SD 14]; 30 [58%] male and 22 [42%] female) were included in the analysis. Patients were assessed at a median of 5·0 months (IQR 4·2–6·3) after hospital discharge. Compared with non-COVID-19 controls, patients were older, living with more obesity, and had more comorbidities. Multiorgan abnormalities on MRI were more frequent in patients than in controls (157 [61%] of 259 vs 14 [27%] of 52; p<0·0001) and independently associated with COVID-19 status (odds ratio [OR] 2·9 [95% CI 1·5–5·8]; padjusted=0·0023) after adjusting for relevant confounders. Compared with controls, patients were more likely to have MRI evidence of lung abnormalities (p=0·0001; parenchymal abnormalities), brain abnormalities (p<0·0001; more white matter hyperintensities and regional brain volume reduction), and kidney abnormalities (p=0·014; lower medullary T1 and loss of corticomedullary differentiation), whereas cardiac and liver MRI abnormalities were similar between patients and controls. Patients with multiorgan abnormalities were older (difference in mean age 7 years [95% CI 4–10]; mean age of 59·8 years [SD 11·7] with multiorgan abnormalities vs mean age of 52·8 years [11·9] without multiorgan abnormalities; p<0·0001), more likely to have three or more comorbidities (OR 2·47 [1·32–4·82]; padjusted=0·0059), and more likely to have a more severe acute infection (acute CRP >5mg/L, OR 3·55 [1·23–11·88]; padjusted=0·025) than those without multiorgan abnormalities. Presence of lung MRI abnormalities was associated with a two-fold higher risk of chest tightness, and multiorgan MRI abnormalities were associated with severe and very severe persistent physical and mental health impairment (PHOSP-COVID symptom clusters) after hospitalisation. Interpretation: After hospitalisation for COVID-19, people are at risk of multiorgan abnormalities in the medium term. Our findings emphasise the need for proactive multidisciplinary care pathways, with the potential for imaging to guide surveillance frequency and therapeutic stratification

What cognitive strategies do orangutans (Pongo pygmaeus) use to solve a trial-unique puzzle-tube task incorporating multiple obstacles?

Apparently sophisticated behaviour during problem-solving is often the product of simple underlying mechanisms, such as associative learning or the use of procedural rules. These and other more parsimonious explanations need to be eliminated before higher-level cognitive processes such as causal reasoning or planning can be inferred. We presented three Bornean orangutans with 64 trial-unique configurations of a puzzle-tube to investigate whether they were able to consider multiple obstacles in two alternative paths, and subsequently choose the correct direction in which to move a reward in order to retrieve it. We were particularly interested in how subjects attempted to solve the task, namely which behavioural strategies they could have been using, as this is how we may begin to elucidate the cognitive mechanisms underpinning their choices. To explore this, we simulated performance outcomes across the 64 trials for various procedural rules and rule combinations that subjects may have been using based on the configuration of different obstacles. Two of the three subjects solved the task, suggesting that they were able to consider at least some of the obstacles in the puzzle-tube before executing action to retrieve the reward. This is impressive compared with the past performances of great apes on similar, arguably less complex tasks. Successful subjects may have been using a heuristic rule combination based on what they deemed to be the most relevant cue (the configuration of the puzzle-tube ends), which may be a cognitively economical strategy

What cognitive strategies do orangutans (Pongo pygmaeus) use to solve a trial-unique puzzle-tube task incorporating multiple obstacles?

Apparently sophisticated behaviour during problem-solving is often the product of simple underlying mechanisms, such as associative learning or the use of procedural rules. These and other more parsimonious explanations need to be eliminated before higher-level cognitive processes such as causal reasoning or planning can be inferred. We presented three Bornean orangutans with 64 trial-unique configurations of a puzzle-tube to investigate whether they were able to consider multiple obstacles in two alternative paths, and subsequently choose the correct direction in which to move a reward in order to retrieve it. We were particularly interested in how subjects attempted to solve the task, namely which behavioural strategies they could have been using, as this is how we may begin to elucidate the cognitive mechanisms underpinning their choices. To explore this, we simulated performance outcomes across the 64 trials for various procedural rules and rule combinations that subjects may have been using based on the configuration of different obstacles. Two of the three subjects solved the task, suggesting that they were able to consider at least some of the obstacles in the puzzle-tube before executing action to retrieve the reward. This is impressive compared with the past performances of great apes on similar, arguably less complex tasks. Successful subjects may have been using a heuristic rule combination based on what they deemed to be the most relevant cue (the configuration of the puzzle-tube ends), which may be a cognitively economical strategy

Development of planning in 4- to 10-year-old children:reducing inhibitory demands does not improve performance

Currently, there are relatively few tasks suitable for testing planned problem solving in children. We presented 4- to 10-year-old children (N = 172) with two planning tasks (sequential planning and advance planning) using the paddle-box apparatus, which was originally designed to investigate the planning skills of nonhuman apes. First, we were interested in the development of children’s performance in the two tasks and whether the strategies children used to succeed differed among age groups. Performance improved significantly across age groups in both tasks. Strategies for success in the advance planning task differed among age groups, with 4- and 5-year-olds performing more excess actions, and a greater proportion of irrelevant excess actions, than older children. Findings are discussed in relation to the development of performance in tower tasks, which are a commonly used test of planning ability in humans. Second, based on previous findings with apes, we predicted that introducing measures to reduce the inhibitory demands of the advance planning task would improve children’s performance. Therefore, in this study we introduced two methodological alterations that have been shown to improve children’s performance in other tasks with inhibitory demands: (a) imposing a short delay before a child is allowed to act and (b) replacing reward items with symbolic tokens. Surprisingly, neither of these measures improved the performance of children in any of the age groups, suggesting that, contrary to our prediction, inhibitory control might not be a key performance-limiting factor in the advance planning paddle-box task

Development of planning in 4- to 10-year-old children:reducing inhibitory demands does not improve performance

Currently, there are relatively few tasks suitable for testing planned problem solving in children. We presented 4- to 10-year-old children (N = 172) with two planning tasks (sequential planning and advance planning) using the paddle-box apparatus, which was originally designed to investigate the planning skills of nonhuman apes. First, we were interested in the development of children’s performance in the two tasks and whether the strategies children used to succeed differed among age groups. Performance improved significantly across age groups in both tasks. Strategies for success in the advance planning task differed among age groups, with 4- and 5-year-olds performing more excess actions, and a greater proportion of irrelevant excess actions, than older children. Findings are discussed in relation to the development of performance in tower tasks, which are a commonly used test of planning ability in humans. Second, based on previous findings with apes, we predicted that introducing measures to reduce the inhibitory demands of the advance planning task would improve children’s performance. Therefore, in this study we introduced two methodological alterations that have been shown to improve children’s performance in other tasks with inhibitory demands: (a) imposing a short delay before a child is allowed to act and (b) replacing reward items with symbolic tokens. Surprisingly, neither of these measures improved the performance of children in any of the age groups, suggesting that, contrary to our prediction, inhibitory control might not be a key performance-limiting factor in the advance planning paddle-box task

Data from: Bridging the gap: parkour athletes provide new insights into locomotion energetics of arboreal apes

The tree canopy is an energetically challenging environment to traverse. Along with compliant vegetation, gaps in the canopy can prove energetically costly if they force a route-extending detour. Arboreal apes exhibit diverse locomotion strategies, including for gap crossing. Which one they employ in any given scenario may be influenced by the energy costs to do so, which are affected by the details of the immediate environment in combination with their body size. Measuring energetics of arboreal apes is not tractable; thus our knowledge in this area is limited. We devised a novel, custom-made experimental set-up to record the energy expenditure of parkour athletes tree-swaying, jumping and vertical climbing. The latter strategy was vastly more expensive, indicating that when energy economy is the focus arboreal apes will prioritize routes that limit height changes. Whether tree-swaying or jumping was most economical for the athletes depended upon interactions between tree stiffness, the distance to cross, number of tree-sways required and their own mass. Updated analysis of previous interspecific correlations suggests that whether the relative costs to vertical climb are size-invariant across primate species is complicated by details of the climbing context