Consensus statements and recommendations from the ESO-Karolinska Stroke Update Conference, Stockholm 11–13 November 2018

The purpose of the European Stroke Organisation–Karolinska Stroke Update Conference is to provide updates on recent stroke therapy research and to give an opportunity for the participants to discuss how these results may be implemented into clinical routine. The meeting started 22 years ago as Karolinska Stroke Update, but since 2014 it is a joint conference with European Stroke Organisation. Importantly, it provides a platform for discussion on the European Stroke Organisation guidelines process and on recommendations to the European Stroke Organisation guidelines committee on specific topics. By this, it adds a direct influence from stroke professionals otherwise not involved in committees and work groups on the guideline procedure. The discussions at the conference may also inspire new guidelines when motivated. The topics raised at the meeting are selected by the scientific programme committee mainly based on recent important scientific publications. This year’s European Stroke Organisation–Karolinska Stroke Update Meeting was held in Stockholm on 11–13 November 2018. There were 11 scientific sessions discussed in the meeting including two short sessions. Each session except the short sessions produced a consensus statement (Full version with background, issues, conclusions and references are published as web-material and at www.eso-karolinska.org and http://eso-stroke.org) and recommendations which were prepared by a writing committee consisting of session chair(s), scientific secretary and speakers. These statements were presented to the 250 participants of the meeting. In the open meeting, general participants commented on the consensus statement and recommendations and the final document were adjusted based on the discussion from the general participants Recommendations (grade of evidence) were graded according to the 1998 Karolinska Stroke Update meeting with regard to the strength of evidence. Grade A Evidence: Strong support from randomised controlled trials and statistical reviews (at least one randomised controlled trial plus one statistical review). Grade B Evidence: Support from randomised controlled trials and statistical reviews (one randomised controlled trial or one statistical review). Grade C Evidence: No reasonable support from randomised controlled trials, recommendations based on small randomised and/or non-randomised controlled trials evidence

Consensus statements and recommendations from the ESO-Karolinska Stroke Update Conference, Stockholm 11-13 November 2018

The purpose of the European Stroke Organisation-Karolinska Stroke Update Conference is to provide updates on recent stroke therapy research and to give an opportunity for the participants to discuss how these results may be implemented into clinical routine. The meeting started 22 years ago as Karolinska Stroke Update, but since 2014 it is a joint conference with European Stroke Organisation. Importantly, it provides a platform for discussion on the European Stroke Organisation guidelines process and on recommendations to the European Stroke Organisation guidelines committee on specific topics. By this, it adds a direct influence from stroke professionals otherwise not involved in committees and work groups on the guideline procedure. The discussions at the conference may also inspire new guidelines when motivated. The topics raised at the meeting are selected by the scientific programme committee mainly based on recent important scientific publications. This year's European Stroke Organisation-Karolinska Stroke Update Meeting was held in Stockholm on 11-13 November 2018. There were 11 scientific sessions discussed in the meeting including two short sessions. Each session except the short sessions produced a consensus statement (Full version with background, issues, conclusions and references are published as web-material and at and ) and recommendations which were prepared by a writing committee consisting of session chair(s), scientific secretary and speakers. These statements were presented to the 250 participants of the meeting. In the open meeting, general participants commented on the consensus statement and recommendations and the final document were adjusted based on the discussion from the general participants Recommendations (grade of evidence) were graded according to the 1998 Karolinska Stroke Update meeting with regard to the strength of evidence. Grade A Evidence: Strong support from randomised controlled trials and statistical reviews (at least one randomised controlled trial plus one statistical review). Grade B Evidence: Support from randomised controlled trials and statistical reviews (one randomised controlled trial or one statistical review). Grade C Evidence: No reasonable support from randomised controlled trials, recommendations based on small randomised and/or non-randomised controlled trials evidence.Peer reviewe

Measurement of e plus e-& RARR; AA & eta; from 3.5106 to 4.6988 GeV and study of AA mass threshold enhancement

Using data samples with a total integrated luminosity of approximately 18 fb-1 collected by the BESIII detector operating at the Beijing Electron-Positron Collider II, the process e+e- &amp; RARR; A over bar A &amp; eta; is studied at center-of-mass energies between 3.5106 and 4.6988 GeV. The Born cross section for the process e+e-&amp; RARR; A over bar A &amp; eta; is measured. No significant structure is observed in the Born cross section line shape. An enhancement near the AA over bar mass threshold is observed for the first time in the process. The structure can be described by an S-wave Breit-Wigner function. Neglecting contribution of excited A states and potential interferences, the mass and width are determined to be (2356 &amp; PLUSMN; 7 &amp; PLUSMN; 15) MeV=c2 and (304 &amp; PLUSMN; 28 &amp; PLUSMN; 54) MeV, respectively, where the first uncertainties are statistical and the second are systematic.For complete list of authors see http://dx.doi.org/10.1103/PhysRevD.107.112001</p

Measurements of the absolute branching fractions of Ω- decays and test of the Î\u94I=1/2 rule

Based on a dataset of (27.12 +/- 0.10) x 10(8) psi(3686) events collected at the BESIII experiment, the absolute branching fractions of the three dominant Omega(-) decays are measured to be B Omega--&gt;Xi 0 pi- = (25.03 +/- 0.44 +/- 0.53) %, B Omega--&gt;Xi-pi 0 = (8.43 +/- 0.52 +/- 0.28) %, and B Omega--&gt;Lambda K- = (66.3 +/- 0.8 +/- 2.0) %, where the first and second uncertainties are statistical and systematic, respectively. The ratio between B Omega--&gt;Xi 0 pi- and B Omega--&gt;Xi-pi 0 is determined to be 2.97 +/- 0.19 +/- 0.11, which is in good agreement with the PDG value of 2.74 +/- 0.15, but greater by more than four standard deviations than the theoretical prediction of 2 obtained from the Delta I = 1/2 rule.For complete list of authors see http://dx.doi.org/10.1103/PhysRevD.108.L091101</p

First observation of Î\u9b+ c â\u86\u92 Î\u9bK+ Ï\u800 and evidence of Î\u9b+ c â\u86\u92 Î\u9bK+ Ï\u80 + Ï\u80 -

We present the first observation of the singly Cabibbo-suppressed decay Lambda thorn c -&gt;Lambda K thorn pi 0with asignificance of5.7 sigma and the first evidence of Lambda thorn c -&gt;Lambda K thorn pi thorn pi-decay with a significance of3.1 sigma,basedone thorn e-annihilation data recorded by the BESIII detector at the BEPCII collider. The data correspond to anintegrated luminosity of6.4fb-1, in the center-of-mass energy range from 4.600 to 4.950 GeV. Wedetermine the branching fractions of Lambda thorn c -&gt;Lambda K thorn pi 0and Lambda thorn c -&gt;Lambda K thorn pi thorn pi-relative to their Cabibbo-favored counterparts to beBo Lambda thorn c -&gt;Lambda K thorn pi 0 thorn Bo Lambda thorn c -&gt;Lambda pi thorn pi 0 thorn 1/4o2.090.39stat0.07syst thorn x10-2andBo Lambda thorn c -&gt;Lambda K thorn pi thorn pi- thorn Bo Lambda thorn c -&gt;Lambda pi thorn pi thorn pi- thorn 1/4o1.130.41stat0.06syst thorn x10-2, respectively. Moreover, by combining our measured result with theworld average ofBo Lambda thorn c -&gt;Lambda pi thorn pi 0 thorn , we obtain the branching fractionBo Lambda thorn c -&gt;Lambda K thorn pi 0 thorn 1/4o1.490.27stat0.05syst0.08ref thorn x10-3. This result significantly departs from theoretical predictionsbased on quarkSUo3 thorn flavor symmetry, which is underpinned by the presumption of meson pairS-waveamplitude dominanceFor complete list of authors see http://dx.doi.org/10.1103/PhysRevD.109.032003</p

Tests of CP symmetry in entangled Î\u9e0- (Î\u9e)over-bar0 pairs

The J/psi -&gt; Xi(0)(Xi) over bar (0) process and subsequent decays are investigated using (10087 +/- 44) x 10(6) J/psi events collected at the BESIII experiment. The decay parameters of Xi(0) and (Xi) over bar (0) are simultaneously measured to be alpha(Xi) = -0.3750 +/- 0.0034 +/- 0.0016, (alpha) over bar (Xi) = 0.3790 +/- 0.0034 +/- 0.0021, phi(Xi) = 0.0051 +/- 0.0096 +/- 0.0018 rad, (phi) over bar (Xi) = -0.0053 +/- 0.0097 +/- 0.0019 rad with unprecedented accuracies, where the first and the second uncertainties are statistical and systematic, respectively. The most precise values for CP asymmetry observables of Xi(0) decay are obtained to be A(CP)(Xi) = (-5.4 +/- 6.5 +/- 3.1) x 10(-3) and Delta phi(Xi)(CP) = (-0.1 +/- 6.9 +/- 0.9) x 10(-3) rad. For the first time, the weak and strong phase differences are determined to be xi(P) - xi(S) = (0.0 +/- 1.7 +/- 0.2) x 10(-2) rad and delta(P) - delta(S) = (-1.3 +/- 1.7 +/- 0.4) x 10(-2) rad, which are the most precise results for any weakly decaying baryon. These results will play important roles in the studies of the CP violations and polarizations for the strange, charmed, and beauty baryons.For complete list of authors see http://dx.doi.org/10.1103/PhysRevD.108.L031106</p

Observation of the Ï\u88ð3686ß decays into Σ+ Σ - Ï\u89 and Σ+ Σ - Ï\u86

Based on (2712.4 +/- 14.3) x 106 events recorded at the psi(3686) nominal mass collected with the BESIII detector operating at the BEPCII collider, the psi(3686) -&gt; E +/- E over bar -omega and E +/- E over bar -phi decays are observed for the first time with statistical significances of 13.8 sigma and 7.6 sigma, respectively. The corresponding branching fractions are measured to be B(psi (3686) -&gt; E +/- E over bar -omega) = (1.89 +/- 0.18 +/- 0.21) x 10-5 and B(psi (3686) -&gt; E +/- E over bar -phi) = (2.96 +/- 0.54 +/- 0.41) x 10-6, where the first uncertainties are statistical and the second systematic.For complete list of authors see http://dx.doi.org/10.1103/PhysRevD.108.092011</p

Search for the semileptonic decays Ds+ â\u86\u92 K1(1270)0e+Îœe&lt;/su b&gt; and Ds+ â\u86\u92 b1(1235)0e+Îœe&lt;/su b&gt;

By analyzing 7.33 fb(-1) of e(+)e(-) collision data collected at center-of-mass energies between 4.128 and 4.226 GeV with the BESIII detector, we search for the semileptonic decays D-s(+)-&gt; K-1(1270)(0)e(+)nu(e) and D-s(+)-&gt; b(1)(1235)(0)e(+)nu(e) for the first time. No significant signals are observed for either decay mode. The upper limits on the (product) branching fractions are determined to be B[D-s(+)-&gt; K-1(1270)(0)e(+)nu(e)] &lt; 4.1x10(-4) and B[D-s(+)-&gt; b(1)(1235)(0)e(+)nu(e)]center dot B[b(1)(1235)(0)-&gt;omega pi(0)] &lt; 6.4x10(-4) at 90% confidence level.For complete list of authors see http://dx.doi.org/10.1103/PhysRevD.108.112002</p

Measurements of Σ electromagnetic form factors in the timelike region using the untagged initial-state radiation technique

The process e thorn e- -&gt; sigma thorn sigma over bar - is studied from threshold up to 3.04 GeV=c2 via the initial -state radiation technique using data with an integrated luminosity of 12.0 fb-1, collected at center-of-mass energies between 3.773 and 4.258 GeV with the BESIII detector at the BEPCII collider. The pair production cross sections and the effective form factors of sigma are measured in eleven sigma thorn sigma over bar - invariant mass intervals from threshold to 3.04 GeV=c2. The results are consistent with the previous results from Belle and BESIII. Furthermore, the branching fractions of the decays J=psi -&gt;sigma thorn sigma over bar - and psi o3686 thorn -&gt; sigma thorn sigma over bar - are determined and the obtained results are consistent with the previous results of BESIII.For complete list of authors see http://dx.doi.org/10.1103/PhysRevD.109.034029</p

Search for the light hadron decay Ï\u87c1(3872) â\u86\u92 Ï\u80+Ï\u80-η

With a data sample corresponding to an integrated luminosity of 11.5 fb(-1) collected with the BESIII detector operating at the BEPCII storage ring, for the first time the light hadron decay chi(c1()3872)-&gt;pi(+)pi(-)eta is searched for. While no significant signal is observed, the upper limits at the 90% confidence level for sigma[e(+)e(-)-&gt;gamma chi(c1)(3872)]B[chi(c1)(3872)-&gt;pi(+)pi(-)eta] at center of mass energies from 4.13 GeV to 4.34 GeV are determined. By normalizing to the chi(c1)(3872)-&gt;pi(+)pi(-)J/psi decay channel, a 90% confidence level upper limit for the branching fraction ratio R=B[chi(c1)(3872)-&gt;pi(+)pi(-)eta]/B[chi(c1)(3872)-&gt;pi(+)pi(-)J/psi]&lt;0.12 is given. These measurements provide important inputs for understanding the internal structure of the chi(c1)(3872) resonanceFor complete list of authors see http://dx.doi.org/10.1103/PhysRevD.109.L011102</p