2,590 research outputs found
Feline immunodeficiency virus (FIV) infection in domestic pet cats in Australia and New Zealand: Guidelines for diagnosis, prevention and management
Despite the passage of over 30 years since its discovery, the importance of feline immunodeficiency virus (FIV) on the health and longevity of infected domestic cats is hotly debated amongst feline experts. Notwithstanding the absence of good quality information, Australian and New Zealand (NZ) veterinarians should aim to minimise the exposure of cats to FIV. The most reliable way to achieve this goal is to recommend that all pet cats are kept exclusively indoors, or with secure outdoor access (e.g., cat enclosures, secure gardens), with FIV testing of any in-contact cats. All animal holding facilities should aim to individually house adult cats to limit the spread of FIV infection in groups of animals that are stressed and do not have established social hierarchies. Point-of-care (PoC) FIV antibody tests are available in Australia and NZ that can distinguish FIV-infected and uninfected FIV-vaccinated cats (Witness™ and Anigen Rapid™). Although testing of whole blood, serum or plasma remains the gold standard for FIV diagnosis, PoC testing using saliva may offer a welfare-friendly alternative in the future. PCR testing to detect FIV infection is not recommended as a screening procedure since a negative PCR result does not rule out FIV infection and is only recommended in specific scenarios. Australia and NZ are two of three countries where a dual subtype FIV vaccine (Fel-O-Vax® FIV) is available and offers a further avenue for disease prevention. Since FIV vaccination only has a reported field effectiveness of 56% in Australia, and possibly lower in NZ, FIV-vaccinated cats should undergo annual FIV testing prior to annual FIV re-vaccination using a suitable PoC kit to check infection has not occurred in the preceding year. With FIV-infected cats, clinicians should strive to be even more thorough than usual at detecting early signs of disease. The most effective way to enhance the quality of life and life expectancy of FIV-infected cats is to optimise basic husbandry and to treat any concurrent conditions early in the disease course. Currently, no available drugs are registered for the treatment of FIV infection. Critically, the euthanasia of healthy FIV-infected cats, and sick FIV-infected cats without appropriate clinical investigations, should not occur
Is web interviewing a good alternative to telephone interviewing? Findings from the International Tobacco Control (ITC) Netherlands survey
Mediational pathways of the impact of cigarette warning labels on quit attempts
OBJECTIVES: To test and develop, using structural equation modelling, a robust model of the mediational pathways through which health warning labels exert their influence on smokers’ subsequent quitting behaviour. METHODS: Data come from the International Tobacco Control Four-Country Survey, a longitudinal cohort study conducted in Australia, Canada, the UK, and the US. Waves 5–6 data (n=4988) were used to calibrate the hypothesized model of warning label impact on subsequent quit attempts via a set of policy-specific and general psychosocial mediators. The finalised model was validated using Waves 6–7 data (n=5065). RESULTS: As hypothesized, warning label salience was positively associated with thoughts about risks of smoking stimulated by the warnings (β=.58, p<.001), which in turn were positively related to increased worry about negative outcomes of smoking (β=.52, p<.001); increased worry in turn predicted stronger intention to quit (β=.39, p<.001) which was a strong predictor of subsequent quit attempts (β=.39, p<.001). This calibrated model was successfully replicated using Waves 6–7 data. CONCLUSIONS: Health warning labels seem to influence future quitting attempts primarily through their ability to stimulate thoughts about the risks of smoking, which in turn help to raise smoking-related health concerns, which lead to stronger intentions to quit, a known key predictor of future quit attempts for smokers. By making warning labels more salient and engaging, they should have a greater chance to change behaviour
Selectron Studies at e-e- and e+e- Colliders
Selectrons may be studied in both e-e- and e+e- collisions at future linear
colliders. Relative to e+e-, the e-e- mode benefits from negligible backgrounds
and \beta threshold behavior for identical selectron pair production, but
suffers from luminosity degradation and increased initial state radiation and
beamstrahlung. We include all of these effects and compare the potential for
selectron mass measurements in the two modes. The virtues of the e-e- collider
far outweigh its disadvantages. In particular, the selectron mass may be
measured to 100 MeV with a total integrated luminosity of 1 fb^-1, while more
than 100 fb^-1 is required in e+e- collisions for similar precision.Comment: 16 pages, 11 figure
Fine particle retention and deposition in regions of cyclonic tidal current rotation
Benthic sediments in continental shelf seas control a variety of biogeochemical processes, yet their composition, especially that of fine sediment, remains difficult to predict. Mechanisms for mud or fine sediment deposition and retention are not fully understood. Using sediment data and a hydrodynamic model of the Northwest European shelf seas, a relationship is shown to exist between fine benthic sediment composition and regions of cyclonic tidal current rotation. The reduced thickness of cyclonic tidal benthic boundary layers compared with the anticyclonic case promotes deposition of fine sediment and trapping of resuspended material. Adding the effects of the benthic boundary layer thickness, as influenced by ellipticity or not, sheds some light on the limitations of approaches only focusing on bed shear stress and sediment pathways to predict the location of mud deposits. A tidal boundary layer predictor that includes ellipticity alongside tidal current magnitude and depth was shown to spatially agree with maps of mud deposits
Molecular and phylogenetic analysis of Cryptosporidium muris from various hosts
Isolates of Cryptosporidium muris and C. serpentis were characterized from different hosts using nucleotide sequence analysis of the rDNA 18S and ITS1 regions, and the heat-shock (HSP-70) gene. Phylogenetic analysis confirmed preliminary evidence that C. muris is not a uniform species. Two distinct genotypes were identified within C. muris; (1) C. muris genotype A; comprising bovine and camel isolates of C. muris from different geographical locations, and (2) C. muris genotype B comprising C. muris isolates from mice, a hamster, a rock hyrax and a camel from the same enclosure. These 2 genotypes may represent separate species but further biological and molecular studies are required for confirmation
Space Weathering on Near-Earth Objects investigated by neutral-particle detection
The ion-sputtering (IS) process is active in many planetary environments in
the Solar System where plasma precipitates directly on the surface (for
instance, Mercury, Moon, Europa). In particular, solar-wind sputtering is one
of the most important agents for the surface erosion of a Near-Earth Object
(NEO), acting together with other surface release processes, such as Photon
Stimulated Desorption (PSD), Thermal Desorption (TD) and Micrometeoroid Impact
Vaporization (MIV). The energy distribution of the IS-released neutrals peaks
at a few eVs and extends up to hundreds of eVs. Since all other release
processes produce particles of lower energies, the presence of neutral atoms in
the energy range above 10 eV and below a few keVs (Sputtered High-Energy Atoms
- SHEA) identifies the IS process. SHEA easily escape from the NEO, due to
NEO's extremely weak gravity. Detection and analysis of SHEA will give
important information on surface-loss processes as well as on surface elemental
composition. The investigation of the active release processes, as a function
of the external conditions and the NEO surface properties, is crucial for
obtaining a clear view of the body's present loss rate as well as for getting
clues on its evolution, which depends significantly on space weather. In this
work, an attempt to analyze the processes that take place on the surface of
these small airless bodies, as a result of their exposure to the space
environment, has been realized. For this reason a new space weathering model
(Space Weathering on NEO - SPAWN), is presented. Moreover, an instrument
concept of a neutral-particle analyzer specifically designed for the
measurement of neutral density and the detection of SHEA from a NEO is proposedComment: 36 page
Mechanisms for slow strengthening in granular materials
Several mechanisms cause a granular material to strengthen over time at low
applied stress. The strength is determined from the maximum frictional force
F_max experienced by a shearing plate in contact with wet or dry granular
material after the layer has been at rest for a waiting time \tau. The layer
strength increases roughly logarithmically with \tau -only- if a shear stress
is applied during the waiting time. The mechanisms of strengthening are
investigated by sensitive displacement measurements and by imaging of particle
motion in the shear zone. Granular matter can strengthen due to a slow shift in
the particle arrangement under shear stress. Humidity also leads to
strengthening, but is found not to be its sole cause. In addition to these time
dependent effects, the static friction coefficient can also be increased by
compaction of the granular material under some circumstances, and by cycling of
the applied shear stress.Comment: 21 pages, 11 figures, submitted to Phys. Rev.
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