4,193 research outputs found
TEXES Observations of Pure Rotational H_2 Emission from AB Aurigae
We present observations of pure rotational molecular hydrogen emission from the Herbig Ae star, AB Aur. Our observations were made using the Texas Echelon Cross Echelle Spectrograph (TEXES) at the NASA Infrared Telescope Facility and the Gemini North Observatory. We searched for H_2 emission in the S(1), S(2), and S(4) lines at high spectral resolution and detected all three. By fitting a simple model for the emission in the three transitions, we derive T = 670 ± 40 K and M = 0.52 ± 0.15 M_⊙ for the emitting gas. On the basis of the 8.5 km s^(-1) FWHM of the S(2) line, assuming the emission comes from the circumstellar disk, and with an inclination estimate of the AB Aur system taken from the literature, we place the location for the emission near 18 AU. Comparison of our derived temperature to a disk structure model suggests that UV and X-ray heating are important in heating the disk atmosphere
H2 Mid-IR Pure Rotational Emission from Young Stars: The TEXES/IRTF Survey
We describe the TEXES survey for mid-IR H2 pure rotational emission from
young stars and report early successes. H2 emission is a potential tracer of
warm gas in circumstellar disks. Three pure rotational lines are available from
the ground: the J=3=>1, J=4=>2, and J=6=>4, transitions at 17.035 microns,
12.279 microns, and 8.025 microns, respectively. Using TEXES at the NASA IRTF
3m, we are midway through a survey of roughly 30 pre-main-sequence stars. To
date, detected lines are all resolved, generally with FWHM<10 km/s. Preliminary
analysis suggests the gas temperatures are between 400 and 800 K. From the work
so far, we conclude that high spectral and spatial resolution are critical to
the investigation of H2 in disks.Comment: 6 pages, to appear in Proceedings of the ESO Workshop on "High
Resolution Infrared Spectroscopy in Astronomy" held in Garching, Germany,
18-21 November 200
Complete intracranial response to talimogene laherparepvec (T-Vec), pembrolizumab and whole brain radiotherapy in a patient with melanoma brain metastases refractory to dual checkpoint-inhibition
Background
Immunotherapy, in particular checkpoint blockade, has changed the clinical landscape of metastatic melanoma. Nonetheless, the majority of patients will either be primary refractory or progress over follow up. Management of patients progressing on first-line immunotherapy remains challenging. Expanded treatment options with combination immunotherapy has demonstrated efficacy in patients previously unresponsive to single agent or alternative combination therapy.
Case presentation
We describe the case of a patient with diffusely metastatic melanoma, including brain metastases, who, despite being treated with stereotactic radiosurgery and dual CTLA-4/PD-1 blockade (ipilimumab/nivolumab), developed systemic disease progression and innumerable brain metastases. This patient achieved a complete CNS response and partial systemic response with standard whole brain radiation therapy (WBRT) combined with Talimogene laherparepvec (T-Vec) and pembrolizumab.
Conclusion
Patients who do not respond to one immunotherapy combination may respond during treatment with an alternate combination, even in the presence of multiple brain metastases. Biomarkers are needed to assist clinicians in evidence based clinical decision making after progression on first line immunotherapy to determine whether response can be achieved with second line immunotherapy
The clustering of galaxies in the SDSS-III Baryon Oscillation Spectroscopic Survey: measuring structure growth using passive galaxies
We explore the benefits of using a passively evolving population of galaxies
to measure the evolution of the rate of structure growth between z=0.25 and
z=0.65 by combining data from the SDSS-I/II and SDSS-III surveys. The
large-scale linear bias of a population of dynamically passive galaxies, which
we select from both surveys, is easily modeled. Knowing the bias evolution
breaks degeneracies inherent to other methodologies, and decreases the
uncertainty in measurements of the rate of structure growth and the
normalization of the galaxy power-spectrum by up to a factor of two. If we
translate our measurements into a constraint on sigma_8(z=0) assuming a
concordance cosmological model and General Relativity (GR), we find that using
a bias model improves our uncertainty by a factor of nearly 1.5. Our results
are consistent with a flat Lambda Cold Dark Matter model and with GR.Comment: Accepted for publication in MNRAS (clarifications added, results and
conclusions unchanged
Assessment of arsenic status and distribution in Usangu agro-ecosystem-Tanzania.
The research article published by Elsevier Ltd., 2021This study was conducted to assess arsenic (As) status and distribution in Usangu agroecosystem-Tanzania, including three land use. About 198 soil samples were collected in ten irrigation schemes in three land uses. Total and bioavailable As were determined by acid digestion (Aqua regia (AQ)) and Mehlich 3 method (M3) to estimate status, distribution and bioavailability. Arsenic concentration were variable among land use and irrigation schemes where total arsenic ranged 567.74-2909.84Â ÎĽg/kg and bioavailable As ranged 26.17-712.37Â ÎĽg/kg. About 12-16% of total arsenic were available for plant uptake. Approximately 86.53% of studied agricultural soils had total As concentration above Tanzania maximum allowable limit. Bioavailable As were lower compared to total As and were within the acceptable threshold. Total arsenic concentration were variable among schemes and higher values were observed in schemes which are highly intensified and mechanized. Thus, this study provides essential site specific preliminary baseline information for As status and distribution in agricultural soils to initiate monitoring and management strategies for increased land productivity and environmental safety
Intrinsic response time of graphene photodetectors
Graphene-based photodetectors are promising new devices for high-speed
optoelectronic applications. However, despite recent efforts, it is not clear
what determines the ultimate speed limit of these devices. Here, we present
measurements of the intrinsic response time of metal-graphene-metal
photodetectors with monolayer graphene using an optical correlation technique
with ultrashort laser pulses. We obtain a response time of 2.1 ps that is
mainly given by the short lifetime of the photogenerated carriers. This time
translates into a bandwidth of ~262 GHz. Moreover, we investigate the
dependence of the response time on gate voltage and illumination laser power
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A new interpretation of total column BrO during Arctic spring
Emission of bromine from sea-salt aerosol, frost flowers, ice leads, and snow results in the nearly complete removal of surface ozone during Arctic spring. Regions of enhanced total column BrO observed by satellites have traditionally been associated with these emissions. However, airborne measurements of BrO and O3 within the convective boundary layer (CBL) during the ARCTAS and ARCPAC field campaigns at times bear little relation to enhanced column BrO. We show that the locations of numerous satellite BrO “hotspots” during Arctic spring are consistent with observations of total column ozone and tropopause height, suggesting a stratospheric origin to these regions of elevated BrO. Tropospheric enhancements of BrO large enough to affect the column abundance are also observed, with important contributions originating from above the CBL. Closure of the budget for total column BrO, albeit with significant uncertainty, is achieved by summing observed tropospheric partial columns with calculated stratospheric partial columns provided that natural, short-lived biogenic bromocarbons supply between 5 and 10 ppt of bromine to the Arctic lowermost stratosphere. Proper understanding of bromine and its effects on atmospheric composition requires accurate treatment of geographic variations in column BrO originating from both the stratosphere and troposphere
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