Die Umstellung auf die Stückaktie für deutsche Aktiengesellschaften

--Stückaktie,Euro,Betragsaktie,Aktienumstellung

The Unfolding of Digital Transformation in Pre-Digital Companies: A Meta-Case Analysis

Due to the growing dispersion of digital technology, many organizations engage in digital transformation. While digital transformation case studies have increased in the information systems and management domain, different ways in which digital transformation unfolds have been proposed. We perform a qualitative meta-analysis of case studies on digital transformation initiatives. From this analysis, we develop two core narratives (a dialectical and a teleological narrative) that we explain in-depth and derive two research avenues from our analysis. Thus, we are advancing the discussion on the unfolding of digital transformation by 1) summarizing existing case studies into two core narratives and 2) shifting the discussion from an explorative character towards a more explanatory approach to better understand how digital transformation unfolds within pre-digital organizations

Selected test results from the LiFeBatt iron phosphate Li-ion battery.

In this paper the performance of the LiFeBatt Li-ion cell was measured using a number of tests including capacity measurements, capacity as a function of temperature, ohmic resistance, spectral impedance, high power partial state of charge (PSOC) pulsed cycling, pulse power measurements, and an over-charge/voltage abuse test. The goal of this work was to evaluate the performance of the iron phosphate Li-ion battery technology for utility applications requiring frequent charges and discharges, such as voltage support, frequency regulation, and wind farm energy smoothing. Test results have indicated that the LiFeBatt battery technology can function up to a 10C{sub 1} discharge rate with minimal energy loss compared to the 1 h discharge rate (1C). The utility PSOC cycle test at up to the 4C{sub 1} pulse rate completed 8,394 PSOC pulsed cycles with a gradual loss in capacity of 10 to 15% depending on how the capacity loss is calculated. The majority of the capacity loss occurred during the initial 2,000 cycles, so it is projected that the LiFeBatt should PSOC cycle well beyond 8,394 cycles with less than 20% capacity loss. The DC ohmic resistance and AC spectral impedance measurements also indicate that there were only very small changes after cycling. Finally, at a 1C charge rate, the over charge/voltage abuse test resulted in the cell venting electrolyte at 110 C after 30 minutes and then open-circuiting at 120 C with no sparks, fire, or voltage across the cell

Mechkit: a continuum mechanics toolkit in Python

Finish JOSS reviewThe research documented in this package and manuscript has been funded by the German Research Foundation (DFG) within the International Research Training Group "Integrated engineering of continuous-discontinuous long fiber-reinforced polymer structures" (GRK 2078/2). The support by the German Research Foundation (DFG) is gratefully acknowledged

A Computational Investigation of Cardiac Caveolae as a Source of Persistent Sodium Current

Recent studies of cholesterol-rich membrane microdomains, called caveolae, reveal that caveolae are reservoirs of “recruitable” sodium ion channels. Caveolar channels constitute a substantial and previously unrecognized source of sodium current in cardiac cells. In this paper we model for the first time caveolar sodium currents and their contributions to cardiac action potential morphology. We show that the β-agonist-induced opening of caveolae may have substantial impacts on peak overshoot, maximum upstroke velocity, and ultimately conduction velocity. Additionally, we show that prolonged action potentials and the formation of potentially arrhythmogenic afterdepolarizations, can arise if caveolae open intermittently throughout the action potential. Our simulations suggest that caveolar sodium current may constitute a route, which is independent of channelopathies, to delayed repolarization and the arrhythmias associated with such delays

Nonstationary Collisional Dynamics in Determining Nitric Oxide Laser-Induced Flourescence Spectra

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/77237/1/AIAA-8783-947.pd

Voltage-gated Nav channel targeting in the heart requires an ankyrin-G–dependent cellular pathway

Voltage-gated Nav channels are required for normal electrical activity in neurons, skeletal muscle, and cardiomyocytes. In the heart, Nav1.5 is the predominant Nav channel, and Nav1.5-dependent activity regulates rapid upstroke of the cardiac action potential. Nav1.5 activity requires precise localization at specialized cardiomyocyte membrane domains. However, the molecular mechanisms underlying Nav channel trafficking in the heart are unknown. In this paper, we demonstrate that ankyrin-G is required for Nav1.5 targeting in the heart. Cardiomyocytes with reduced ankyrin-G display reduced Nav1.5 expression, abnormal Nav1.5 membrane targeting, and reduced Na+ channel current density. We define the structural requirements on ankyrin-G for Nav1.5 interactions and demonstrate that loss of Nav1.5 targeting is caused by the loss of direct Nav1.5–ankyrin-G interaction. These data are the first report of a cellular pathway required for Nav channel trafficking in the heart and suggest that ankyrin-G is critical for cardiac depolarization and Nav channel organization in multiple excitable tissues

Majorana: from atomic and molecular, to nuclear physics

In the centennial of Ettore Majorana's birth (1906-1938?), we re-examine some aspects of his fundamental scientific production in atomic and molecular physics, including a not well known short communication. There, Majorana critically discusses Fermi's solution of the celebrated Thomas-Fermi equation for electron screening in atoms and positive ions. We argue that some of Majorana's seminal contributions in molecular physics already prelude to the idea of exchange interactions (or Heisenberg-Majorana forces) in his later workson theoretical nuclear physics. In all his papers, he tended to emphasize the symmetries at the basis of a physical problem, as well as the limitations, rather than the advantages, of the approximations of the method employed.Comment: to appear in Found. Phy

NM-300 Silver Characterisation, Stability, Homogeneity

This report describes the characteriation of NM-300, a nano-silver reference material used in the context of risk and exposure assessment studies. The material was produced in the context of the JRC IHCP activity on nano-materials. A representative set test items was handed over to the JRC IES analytical laboratory for further characterisation. First, inorganic chemical characterisation of the total silver content and the homogeneity of the Ag-distribution was done using ICP-AES. To this end, a dedicated method was developed and validated according to the requirements laid down in ISO 17025. This works were completed by different types of microscopy analyses (Scanning Electron Microscope, Transmission Electron Microscope and Nanoparticle Tracking Analysis) performed in close collaboration with the German Institute of Energy and Environmental Technology e.V. (IUTA), the Swiss Federal Laboratories for Materials Science and Technology (EMPA) and Belgium Veterinary and Agrochemical Research Centre (VAR). This report summarises all technical details and discusses the assessments made.JRC.DG.I.5-Nanobioscience