1,569 research outputs found

    Broadening of a nonequilibrium phase transition by extended structural defects

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    We study the effects of quenched extended impurities on nonequilibrium phase transitions in the directed percolation universality class. We show that these impurities have a dramatic effect: they completely destroy the sharp phase transition by smearing. This is caused by rare strongly coupled spatial regions which can undergo the phase transition independently from the bulk system. We use extremal statistics to determine the stationary state as well as the dynamics in the tail of the smeared transition, and we illustrate the results by computer simulations.Comment: 4 pages, 4 eps figures, final version as publishe

    Convergence to Fleming-Viot processes in the weak atomic topology

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    AbstractStochastic models for gene frequencies can be viewed as probability-measure-valued processes. Fleming and Viot introduced a class of processes that arise as limits of genetic models as the population size and the number of possible genetic types tend to infinity. In general, the topology on the process values in which these limits exist is the topology of weak convergence; however, convergence in the weak topology is not strong enough for many genetic applications. A new topology on the space of finite measures is introduced in which convergence implies convergence of the sizes and locations of atoms, and conditions are given under which genetic models converge in this topology. As an application, Kingman's Poisson-Dirichlet limit is extended to models with selection

    Quantification of bioactive compound content in advanced fenugreek lines selected in Alberta: levels of galactomannan

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    Non-Peer ReviewedFenugreek (Trigonella foenum-graecum L.) was initially introduced to Alberta as a spice and forage crop. Numerous animal and clinical studies have associated the medicinal properties of the plant with galactomannan, diosgenin and 4-hydroxyisoleucine, the three major bioactive compounds found in fenugreek seed. These bioactive molecules have been demonstrated to regulate plasma cholesterol levels, reduce plasma triglyceride concentrations and stimulate insulin secretion for blood glucose metabolism. Fourteen advanced lines grown satisfactorily in southern Alberta were selected for quantification of these compounds over two harvest seasons. These lines were grown at three locations (Brooks, Bow Island and Lethbridge) in southern Alberta under two growing conditions (rain-fed or irrigated). In this study we report on five different seed lines which possessed a high galactomannan yield during the study; i.e., seed lines F75, L3312, CDC Quatro, F80 and L3308. Seed line F75 was the only line that performed well across all locations and growing conditions. It was observed that seed yield had a greater influence on galactomannan yield compared to seed galactomannan content. This suggests that cultivation of fenugreek plants for neutraceutical purposes should emphasize lines with high seed yield, as galactomannan content does not vary significantly among lines. An understanding of the interaction of bioactive compound content with respective ecotypes will assist in the selection of lines for their economic potential in the functional food and natural health product industry

    The Neon Abundance in the Ejecta of QU Vul From Late-Epoch IR Spectra

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    We present ground-based SpectroCam-10 mid-infrared, MMT optical, and Spitzer Space Telescope IRS mid-infrared spectra taken 7.62, 18.75, and 19.38 years respectively after the outburst of the old classical nova QU Vulpeculae (Nova Vul 1984 #2). The spectra of the ejecta are dominated by forbidden line emission from neon and oxygen. Our analysis shows that neon was, at the first and last epochs respectively, more than 76 and 168 times overabundant by number with respect to hydrogen compared to the solar value. These high lower limits to the neon abundance confirm that QU Vul involved a thermonuclear runaway on an ONeMg white dwarf and approach the yields predicted by models of the nucleosynthesis in such events.Comment: ApJ 2007 accepted, 18 pages, including 5 figures, 1 tabl

    Disease trajectories, place and mode of death in people with head and neck cancer: findings from the ‘Head and Neck 5000’ population-based prospective clinical cohort study

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    Background: Few large studies describe initial disease trajectories and subsequent mortality in people with head and neck cancer. This is a necessary first step to identify the need for palliative care and associated services. Aim: To analyse data from the Head and Neck 5000 study to present mortality, place and mode of death within 12 months of diagnosis. Design: Prospective cohort study. Participants: In total, 5402 people with a new diagnosis of head and neck cancer were recruited from 76 cancer centres in the United Kingdom between April 2011 and December 2014. Results: Initially, 161/5402 (3%) and 5241/5402 (97%) of participants were treated with ‘non-curative’ and ‘curative’ intent respectively. Within 12 months, 109/161 (68%) in the ‘non-curative’ group died compared with 482/5241 (9%) in the ‘curative’ group. Catastrophic bleed was the terminal event for 10.4% and 9.8% of people in ‘non-curative’ and ‘curative’ groups respectively; terminal airway obstruction was recorded for 7.5% and 6.3% of people in the same corresponding groups. Similar proportions of people in both groups died in a hospice (22.9% ‘non-curative’; 23.5% ‘curative’) and 45.7% of the ‘curative’ group died in hospital. Conclusions: In addition to those with incurable head and neck cancer, there is a small but significant ‘curative’ subgroup of people who may have palliative needs shortly following diagnosis. Given the high mortality, risk of acute catastrophic event and frequent hospital death, clarifying the level and timing of palliative care services engagement would help provide assurance as to whether palliative care needs are being met

    The effect of rare regions on a disordered itinerant quantum antiferromagnet with cubic anisotropy

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    We study the quantum phase transition of an itinerant antiferromagnet with cubic anisotropy in the presence of quenched disorder, paying particular attention to the locally ordered spatial regions that form in the Griffiths region. We derive an effective action where these rare regions are described in terms of static annealed disorder. A one loop renormalization group analysis of the effective action shows that for order parameter dimensions p<4p<4 the rare regions destroy the conventional critical behavior. For order parameter dimensions p>4p>4 the critical behavior is not influenced by the rare regions, it is described by the conventional dirty cubic fixed point. We also discuss the influence of the rare regions on the fluctuation-driven first-order transition in this system.Comment: 6 pages RevTe

    Exponential distribution of long heart beat intervals during atrial fibrillation and their relevance for white noise behaviour in power spectrum

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    The statistical properties of heart beat intervals of 130 long-term surface electrocardiogram recordings during atrial fibrillation (AF) are investigated. We find that the distribution of interbeat intervals exhibits a characteristic exponential tail, which is absent during sinus rhythm, as tested in a corresponding control study with 72 healthy persons. The rate of the exponential decay lies in the range 3-12 Hz and shows diurnal variations. It equals, up to statistical uncertainties, the level of the previously uncovered white noise part in the power spectrum, which is also characteristic for AF. The overall statistical features can be described by decomposing the intervals into two statistically independent times, where the first one is associated with a correlated process with 1/f noise characteristics, while the second one belongs to an uncorrelated process and is responsible for the exponential tail. It is suggested to use the rate of the exponential decay as a further parameter for a better classification of AF and for the medical diagnosis. The relevance of the findings with respect to a general understanding of AF is pointed out

    Decreasing sprint duration from 20 to 10 s during reduced-exertion high-intensity interval training (REHIT) attenuates the increase in maximal aerobic capacity but has no effect on affective and perceptual responses

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    Purpose: Recent studies have demonstrated that modifying the ‘classic’ 6x30-s ‘all-out’ sprint interval training (SIT) protocol by incorporating either shorter sprints (6x10-s or 15-s sprints) or fewer sprints (e.g. 2x20-s sprints; reduced-exertion high-intensity interval training (REHIT)) does not attenuate the training-induced improvements in maximal aerobic capacity (V̇O2max). The aim of the present study was to determine whether reducing the sprint duration in the REHIT protocol from 20 s to 10 s per sprint influences acute affective responses and the change in V̇O2max following training. Methods: Thirty-six sedentary or recreationally active participants (17 women; mean±SD age: 22±3 y, BMI: 24.5±4.6 kg·m-2, V̇O2max: 37±8 mL·kg-1·min-1) were randomised to a group performing a ‘standard’ REHIT protocol involving 2x20-s sprints or a group who performed 2x10-s sprints. V̇O2max was determined before and after 6 weeks of 3 weekly training sessions. Acute affective responses and perceived exertion were assessed during training. Results: Greater increases in V̇O2max were observed for the group performing 20-s sprints (2.77±0.75 to 3.04±0.75 L·min-1; +10%) compared to the group performing 10-s sprints (2.58±0.57 vs. 2.67±3.04 L·min-1; +4%; group×time interaction effect: p<0.05; d=1.06). Positive affect and the mood state vigour increased post-exercise, while tension, depression and total mood disturbance decreased, and negative affect remained unchanged. Affective responses and perceived exertion were not altered by training and were not different between groups. Conclusion: Reducing sprint duration in the REHIT protocol from 20 s to 10 s attenuates improvements in V̇O2max, and does not result in more positive affective responses or lower perceived exertion

    On the critical behavior of disordered quantum magnets: The relevance of rare regions

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    The effects of quenched disorder on the critical properties of itinerant quantum antiferromagnets and ferromagnets are considered. Particular attention is paid to locally ordered spatial regions that are formed in the presence of quenched disorder even when the bulk system is still in the paramagnetic phase. These rare regions or local moments are reflected in the existence of spatially inhomogeneous saddle points of the Landau-Ginzburg-Wilson functional. We derive an effective theory that takes into account small fluctuations around all of these saddle points. The resulting free energy functional contains a new term in addition to those obtained within the conventional perturbative approach, and it comprises what would be considered non-perturbative effects within the latter. A renormalization group analysis shows that in the case of antiferromagnets, the previously found critical fixed point is unstable with respect to this new term, and that no stable critical fixed point exists at one-loop order. This is contrasted with the case of itinerant ferromagnets, where we find that the previously found critical behavior is unaffected by the rare regions due to an effective long-ranged interaction between the order parameter fluctuations.Comment: 16 pp., REVTeX, epsf, 2 figs, final version as publishe
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