Arts and Humanities Research Evaluation: No Metrics Please, Just Data

Purpose – The purpose of this paper is to make an explicit case for the use of data with contextual information as evidence in arts and humanities research evaluations rather than systematic metrics. Design/methodology/approach – A survey of the strengths and limitations of citation-based indicators is combined with evidence about existing uses of wider impact data in the arts and humanities, with particular reference to the 2014 UK Research Excellence Framework. Findings – Data are already used as impact evidence in the arts and humanities but this practice should become more widespread. Practical implications – Arts and humanities researchers should be encouraged to think creatively about the kinds of data that they may be able to generate in support of the value of their research and should not rely upon standardised metrics. Originality/value – This paper combines practices emerging in the arts and humanities with research evaluation from a scientometric perspective to generate new recommendations

FLAG assay as a novel method for real-time signal generation during PCR: application to detection and genotyping of KRAS codon 12 mutations

Real-time signal generation methods for detection and characterization of low-abundance mutations in genomic DNA are powerful tools for cancer diagnosis and prognosis. Mutations in codon 12 of the oncogene KRAS, for example, are frequently found in several types of human cancers. We have developed a novel real-time PCR technology, FLAG (FLuorescent Amplicon Generation) and adapted it for simultaneously (i) amplifying mutated codon 12 KRAS sequences, (ii) monitoring in real-time the amplification and (iii) genotyping the exact nucleotide alteration. FLAG utilizes the exceptionally thermostable endonuclease PspGI for real-time signal generation by cleavage of quenched fluorophores from the 5′-end of the PCR products and, concurrently, for selecting KRAS mutations over wild type. By including peptide-nucleic-acid probes in the reaction, simultaneous genotyping is achieved that circumvents the requirement for sequencing. FLAG enables high-throughput, closed-tube KRAS mutation detection down to ∼0.1% mutant-to-wild type. The assay was validated on model systems and compared with allele-specific PCR sequencing for screening 27 cancer specimens. Diverse applications of FLAG for real-time PCR or genotyping applications in cancer, virology or infectious diseases are envisioned

International consensus is needed on a core outcome set to advance the evidence of best practice in cancer prehabilitation services and research.

Prehabilitation aims to optimise patients’ physical and psychological status before treatment. The types of outcomes measured to assess the impact of prehabilitation interventions vary across clinical research and service evaluation, limiting the ability to compare between studies and services and to pool data. An international workshop involving academic and clinical experts in cancer prehabilitation was convened in May 2022 at Sheffield Hallam University’s Advanced Wellbeing Research Centre, England. The workshop substantiated calls for a core outcome set to advance knowledge and understanding of best practice in cancer prehabilitation and to develop national and international databases to assess outcomes at a population level

An Explorative Investigation of Referee Abuse in English Rugby League

This article explored the experiences of 89 rugby league referees in England who undertook a mixed methods online survey from the January 9 to March 31, 2017. The results of the survey produced rich data from the open responses, and the quantitative measures are used to support these open responses. Findings identified an established culture of abuse towards referees, a refereeing workforce requiring greater support, better communication with the governing body and, therefore, revisions to existing policy and training. Conclusions identified specific recommendations and policy implications to improve the operational environment and working conditions and increased support for referees. Subscribe to JAS

International consensus is needed on a core outcome set to advance the evidence of best practice in cancer prehabilitation services and research

Prehabilitation aims to optimise patients’ physical and psychological status before treatment. The types of outcomes measured to assess the impact of prehabilitation interventions vary across clinical research and service evaluation, limiting the ability to compare between studies and services and to pool data. An international workshop involving academic and clinical experts in cancer prehabilitation was convened in May 2022 at Sheffield Hallam University’s Advanced Wellbeing Research Centre, England. The workshop substantiated calls for a core outcome set to advance knowledge and understanding of best practice in cancer prehabilitation and to develop national and international databases to assess outcomes at a population level

International consensus is needed on a core outcome set to advance the evidence of best practice in cancer prehabilitation services and research

Prehabilitation aims to optimise patients' physical and psychological status before treatment. The types of outcomes measured to assess the impact of prehabilitation interventions vary across clinical research and service evaluation, limiting the ability to compare between studies and services and to pool data. An international workshop involving academic and clinical experts in cancer prehabilitation was convened in May 2022 at Sheffield Hallam University's Advanced Wellbeing Research Centre, England. The workshop substantiated calls for a core outcome set to advance knowledge and understanding of best practice in cancer prehabilitation and to develop national and international databases to assess outcomes at a population level.</p