Modelling and optimisation of a bimorph piezoelectric cantilever beam in an energy harvesting application

Piezoelectric materials are excellent transducers in converting vibrational energy into electrical energy, and vibration-based piezoelectric generators are seen as an enabling technology for wireless sensor networks, especially in selfpowered devices. This paper proposes an alternative method for predicting the power output of a bimorph cantilever beam using a finite element method for both static and dynamic frequency analyses. Experiments are performed to validate the model and the simulation results. In addition, a novel approach is presented for optimising the structure of the bimorph cantilever beam, by which the power output is maximised and the structural volume is minimised simultaneously. Finally, the results of the optimised design are presented and compared with other designs

Comparison of regional blood flow values measured by radioactive and fluorescent microspheres

Fluorescent microspheres (FM) have become an attractive alternative to radioactive microspheres (RM) for the measurement of regional blood flow (RBF). The aim of the present study was to investigate the comparability of both methods by measuring RBF with FM and RM. Eight anaesthetised pigs received simultaneous, left atrial injections of FM and RM with a diameter of 15 mum at six different time points. Blood reference samples were collected from the descending aorta. RBF was determined in tissue samples of the myocardium, spleen and kidneys of all 8 animals. After radioactivity of the tissue samples was determined, the samples were processed automatically for measuring fluorescence using a recently developed filter device (SPU). RBF was calculated with both the isotope and spectrometric data of both methods for each sample resulting in a total of 10,512 blood flow values. The comparison of the RBF values yielded high linear correlation (mean r(2) = 0.95 +/- 0.03 to 0.97 +/- 0.02) and excellent agreement (bias 5.4-6.7%, precision 9.9-16.5%) of both methods. Our results indicate the validity of MS and of the automated tissue processing technique by means of the SPU. Copyright (C) 2002 S. Karger AG, Basel

Economics of Sourcing Cellulosic Feedstock for Energy Production

This study investigates the economics of supplying wheat straw and corn stover within 100 mile radius of a potential new biorefinery in southeast North Dakota. In particular, straw and stover total delivery costs, potential straw and stover supply sites and least cost transportation routes are identified using a linear programming transport model and a GIS (Geographic Information Systems) mapping system. We show that USDA/NRCS (Natural Resources Conservation Service) future crop residue removal rate policies will be important for determining whether it is economically viable to harvest crop residues as potential feedstock for energy generation. Increase in residue removal rates narrow the size of residue supply areas and consequently result in lowering total transportation costs. There is an economic tradeoff between residue collection density and distance from the biorefinery. Most wheat residues are highly concentrated in the north, some distance from the biorefinery. Relying solely on wheat straw for supply needs require longer transportation distances which increases total cost. Using a combination of wheat and corn residues lowers total transportation costs. Since most wheat/corn residues are densely concentrated in north/south, regional highways would likely be the routes used often to transport the residues, as compared to interstate highways. Increased traffic volumes due to the hauling of crop residues would require additional investment in improving road conditions.Wheat Straw, Corn Stover, Density, Transportation Cost, GIS, Community/Rural/Urban Development, Crop Production/Industries,

Intraflagellar transport delivers tubulin isotypes to sensory cilium middle and distal segments.

Sensory cilia are assembled and maintained by kinesin-2-dependent intraflagellar transport (IFT). We investigated whether two Caenorhabditis elegans α- and β-tubulin isotypes, identified through mutants that lack their cilium distal segments, are delivered to their assembly sites by IFT. Mutations in conserved residues in both tubulins destabilize distal singlet microtubules. One isotype, TBB-4, assembles into microtubules at the tips of the axoneme core and distal segments, where the microtubule tip tracker EB1 is found, and localizes all along the cilium, whereas the other, TBA-5, concentrates in distal singlets. IFT assays, fluorescence recovery after photobleaching analysis and modelling indicate that the continual transport of sub-stoichiometric numbers of these tubulin subunits by the IFT machinery can maintain sensory cilia at their steady-state length

Antithrombin Budapest 3 An antithrombin variant with reduced heparin affinity resulting from the substitution L99F

AbstractThe molecular basis and functional properties of a variant antithrombin (AT) protein. AT Budapest 3, were studied. A single base substitution was identified in codon 99, CTC→TTC, altering the normal leucine to phenylalanine. The proband presented with a history of venous thrombotic disease and was found to be homozygous for the mutation. The variant protein demonstrated reduced heparin affinity and reduced antiproteinase activity in the presence of either unfractionated heparin or the AT-binding heparin pentasaccharide, when compared to normal AT. A small change in the isoelectric point was also identified. The substituted amino acid residue of AT Budapest 3 is located near to the proposed AT heparin binding site, and it is suggested that reduced heparin affinity of the variant protein may result from substitution-induced distortion of positive charge geometry in the binding site and/or changes in its position relative to the rest of the inhibitor molecule

The Political Economy of Myanmar's Transition

This is an Author's Original Manuscript of an article whose final and definitive form, the Version of Record, has been published in the JOURNAL OF CONTEMPORARY ASIA, 07 Feb 2013, copyright Taylor & Francis, available online at: http://www.tandfonline.com/10.1080/00472336.2013.764143.Since holding elections in 2010, Myanmar has transitioned from a direct military dictatorship to a formally democratic system and has embarked on a period of rapid economic reform. After two decades of military rule, the pace of change has startled almost everyone and led to a great deal of cautious optimism. To make sense of the transition and assess the case for optimism, this article explores the political economy of Myanmar's dual transition from state socialism to capitalism and from dictatorship to democracy. It analyses changes within Myanmar society from a critical political economy perspective in order to both situate these developments within broader regional trends and to evaluate the country's current trajectory. In particular, the emergence of state-mediated capitalism and politico-business complexes in Myanmar's borderlands are emphasised. These dynamics, which have empowered a narrow oligarchy, are less likely to be undone by the reform process than to fundamentally shape the contours of reform. Consequently, Myanmar's future may not be unlike those of other Southeast Asian states that have experienced similar developmental trajectories

Polymerization-Induced Phase-Separation in a Liquid-Crystal-Polymer Mixture

We have used light scattering to study the kinetics of polymerization-induced phase separation in a liquid-crystal-polymer mixture. The evolution of the structure factor is compared with scaling predictions for thermally quenched systems. We have also observed a cascading phenomenon where phase separated domains become unstable and undergo phase separation for a second time

Simple guide to starting a research group

Conducting cutting-edge research and scholarship becomes more complicated with each passing year; forming a collaborative research group offers a way to navigate this increasing complexity. Yet many individuals whose work might benefit from the formation of a collaborative team may feel overwhelmed by the prospect of attempting to build and maintain a research group. We propose this simple guide for starting and maintaining such an enterprise