染色体不安定型腺管形成性胃癌のマルチサンプリングによるDNAコピー数プロファイル解析で明らかになった、生長の速い系譜と遅い系譜

Pathobiology. 2019;86(2-3):118-127.滋賀医科大学平成30年

Double-Side Electromagnetic Band Gap Structure for Improving Dual-Band MIMO Antenna Performance

A double-side EBG structure with equivalent circuit model is proposed in this paper. Making H shape on surface and H with bridge shape on ground, the novel EBG that is built on FR4 substrate with height of 1.6mm, gets compact size of 8.6x8.6 mm2 at 2.6 GHz resonant frequency. Using 1x7 EBG structures for dual-band MIMO system, several performance parameters of antenna are improved. Firstly, the mutual coupling between antenna elements gets -40dB in the lower band and -30dB in the higher one with narrow distance of 0.11l from feeding point to feeding point. Then, at 2.6GHz, the antenna gain is increased significant by 160% as well as radiation efficiency of antenna is better. This improvement is unable to get in previous EBG studie

Two-State Migration of DNA in a structured Microchannel

DNA migration in topologically structured microchannels with periodic cavities is investigated experimentally and with Brownian dynamics simulations of a simple bead-spring model. The results are in very good agreement with one another. In particular, the experimentally observed migration order of Lambda- and T2-DNA molecules is reproduced by the simulations. The simulation data indicate that the mobility may depend on the chain length in a nonmonotonic way at high electric fields. This is found to be the signature of a nonequilibrium phase transition between two different migration states, a slow one and a fast one, which can also be observed experimentally under appropriate conditions.Comment: Revised edition corresponding to the comments by the referees, submitted to Physical Review

Using Fine-Grained Sediment and Wave Attenuation as a New Measure for Evaluating the Efficacy of Offshore Breakwaters in Stabilizing an Eroded Muddy Coast: Insights from Ca Mau, the Mekong Delta of Vietnam

Offshore breakwaters can be effective in reducing the energy of incident waves through dissipation, refraction or reflection. Breakwaters are increasingly constructed to stabilize eroded muddy coasts, particularly in developing countries. Accumulation of fine-grained sediment and wave attenuation are two attributes of a stable muddy coast. Effective interventions in stabilizing eroded muddy coasts include two important elements: accumulation of fine-grained sediment and wave reduction. The efficacy of offshore breakwaters in stabilizing eroded muddy coasts is, however, not yet adequately understood. A crucial question needing attention is whether accumulation of fine-grained sediment and wave attenuation should be used in evaluating the efficacy of these offshore breakwaters in stabilizing eroded muddy coasts. To address this issue, a pile-rock offshore breakwater in Huong Mai, Tieu Dua of Ca Mau, Vietnam was selected as an appropriate example in this regard. Accumulation of fine-grained sediment and wave attenuation were tested as means to investigate the efficacy of the Huong Mai structure in stabilizing the eroded muddy coast. The study was undertaken using field-based measurements and semi-structured interviews in three stages between October 2016 and December 2020. We found that this structure has had limited efficacy in stabilizing the eroded muddy coast. The structure was effective in dissipating the energy of incident waves, but we found no evidence of fine-grained sediment accumulation due to an inappropriate structural design. There was also no monitoring system in place, leading to difficulties in evaluating its efficacy in terms of wave attenuation and accumulation of fine-grained sediment. The gaps between the shoreline and the structure have not been adequately explained, resulting in substantial challenges in replicating the structure elsewhere. The Huong Mai structure should be strengthened using supplementary measures and granulometric tests in order to improve the efficacy in stabilizing eroded muddy coasts. The methods in this study provide new insights in this regard

Free vibration analysis of functionally graded shell panels with various geometric shapes in thermal environment

This paper presents free vibration analysis of functionally graded materials (FGMs) shell panels with various geometric shapes in thermal environments. The shell panels are made from a mixture of metal and ceramic. Material properties are assumed to be temperature-dependent and graded in the thickness direction according to a power law function. A formulation of eight-nodded middle surface shell elements based on Reissner-Mindlin assumptions is developed for modeling FGM shell panels under the effect of temperature, which changes nonlinearly across the thickness. Numerical results obtained by the proposed model are in good agreement with those available in the literature. The effects of geometric properties, material composition, boundary conditions and temperature on the natural frequencies are investigated

Seed Health and Quality of Rice Seeds Produced by Farmer and Growing in Cho Moi District, An Giang Province, Vietnam

This study was conducted at Laboratory in An Giang University; the varieties examined were collected from farmer households in 2018 – they were varieties that the farmer stored for the next crop (Winter-Spring) from Autumn-Winter crop in Cho Moi district, An Giang Province, Vietnam. The research evaluated the quality of seed rice, which is provided and planted by the farmer. As a result, this study showed that almost all of the varieties of seed rice from farmer households indicated the ratio of filled-grain, the germination, and the determination of seedling healthy, which are lower than certified variation. Besides, the samples of seed rice from farmer household have more infected fungal; especially the samples with higher in a filled-grain ratio is less infected by fungi, there were 12 types of seed borne-fungi in rice varieties from the farmer (in Cho Moi district), included: Alternaria padwickii, Rhizoctonia solani, Aspergillus oryzae, Bipolaris oryzae, Cercospora janseana, Curvularia lunata, Fusarium moniliforme, Pyricularia oryzae, Sarocladium oryzae, Tilletia barclayana, Fusarium graminearum, and Ustilaginoidea viren

Optical Properties of Silicon Nanoparticles Prepared by Laser Ablation Method in Various Media

Bright photoluminescent silicon nanoparticles were successfully fabricated from porous silicon target in air and n-hexane using 532 nm line of YAG:Nd pulsed laser. The whole procedure was carried out at room temperature, in atmosphere. The morphology and composition of as-synthesized nanoparticles were characterized by SEM and EDS measurements. Their optical properties were investigated. The PL peak position of the as-synthesized Si nanoparticle ablated in air is slightly blue-shifted in comparison with those ablated in n-hexane, while it was almost no change of peak position of Si nanoparticles fabricated from p-Si in hexane and original p-Si wafer target. In contrast to PL intensity quenching of original p-Si sample and particles produced in air, those produced in n-hexane solvent exhibited an enhancement. The presence of dangling bonds or energy transfer from excited Si particles to oxygen molecules on the surface can be the cause of the quenching effect

Characterization of Vibrio cholerae O139 of an Aquatic Isolate in Northern Vietnam

During the cholera survey in Namdinh province (northern Vietnam) in July, 2010, one strain of Vibrio cholerae O139 was isolated from 7 environmental water samples positive for ctxA, toxR, VCO139 genes and named as V. cholerae O139, ND1 strain. This strain was lysogenic harbouring a genome similar to the filamentous phage fs1. The replicative form DNA of this phage (named as ND1-fs1, 6856 bp) was sequenced and compared with the other filamentous phages. The filamentous phage ND1-fs1 integrates into the region between ctxB and rtxA genes. The genetic organization of the CTXϕ of V. cholerae O139, strain ND1 was determined and the schematic representation of the genetic organization was shown together with the ND1-fs1 prophage

Evaluation of Luminex xTAG Gastrointestinal Pathogen Panel Assay for Detection of Multiple Diarrheal Pathogens in Fecal Samples in Vietnam.

Diarrheal disease is a complex syndrome that remains a leading cause of global childhood morbidity and mortality. The diagnosis of enteric pathogens in a timely and precise manner is important for making treatment decisions and informing public health policy, but accurate diagnosis is a major challenge in industrializing countries. Multiplex molecular diagnostic techniques may represent a significant improvement over classical approaches. We evaluated the Luminex xTAG gastrointestinal pathogen panel (GPP) assay for the detection of common enteric bacterial and viral pathogens in Vietnam. Microbiological culture and real-time PCR were used as gold standards. The tests were performed on 479 stool samples collected from people admitted to the hospital for diarrheal disease throughout Vietnam. Sensitivity and specificity were calculated for the xTAG GPP for the seven principal diarrheal etiologies. The sensitivity and specificity for the xTAG GPP were >88% for Shigellaspp.,Campylobacterspp., rotavirus, norovirus genotype 1/2 (GI/GII), and adenovirus compared to those of microbiological culture and/or real-time PCR. However, the specificity was low (∼60%) for Salmonella species. Additionally, a number of important pathogens that are not identified in routine hospital procedures in this setting, such as Cryptosporidiumspp. and Clostridium difficile, were detected with the GPP. The use of the Luminex xTAG GPP for the detection of enteric pathogens in settings, like Vietnam, would dramatically improve the diagnostic accuracy and capacity of hospital laboratories, allowing for timely and appropriate therapy decisions and a wider understanding of the epidemiology of pathogens associated with severe diarrheal disease in low-resource settings