Stable Real-Time Interaction Between Virtual Humans and Real Scenes

We present an augmented reality system that relies on purely passive techniques to solve the real-time registration problem. It can run on a portable PC and does not require engineering of the environment, for example by adding markers. To achieve this result, we have integrated robust computer vision techniques into a powerful VR framework. The resulting AR system allows us to produce complex rendering and animation of virtual human characters, and to blend them into the real world. The system tracks the 3D camera position by means of a natural features tracker, which, given a rough CAD model, can deal with complex 3D objects. The tracking method can handle both large camera displacements and aspect changes. We will show that our system works in the cluttered environment of a real industrial facility and can, therefore, be used to enhance manufacturing and industrial processe

Twisting solar coronal jet launched at the boundary of an active region

A broad jet was observed in a weak magnetic field area at the edge of active region NOAA 11106. The peculiar shape and magnetic environment of the broad jet raised the question of whether it was created by the same physical processes of previously studied jets with reconnection occurring high in the corona. We carried out a multi-wavelength analysis using the EUV images from the Atmospheric Imaging Assembly (AIA) and magnetic fields from the Helioseismic and Magnetic Imager (HMI) both on-board the SDO satellite. The jet consisted of many different threads that expanded in around 10 minutes to about 100 Mm in length, with the bright features in later threads moving faster than in the early ones, reaching a maximum speed of about 200 km s^{-1}. Time-slice analysis revealed a striped pattern of dark and bright strands propagating along the jet, along with apparent damped oscillations across the jet. This is suggestive of a (un)twisting motion in the jet, possibly an Alfven wave. A topological analysis of an extrapolated field was performed. Bald patches in field lines, low-altitude flux ropes, diverging flow patterns, and a null point were identified at the basis of the jet. Unlike classical lambda or Eiffel-tower shaped jets that appear to be caused by reconnection in current sheets containing null points, reconnection in regions containing bald patches seems to be crucial in triggering the present jet. There is no observational evidence that the flux ropes detected in the topological analysis were actually being ejected themselves, as occurs in the violent phase of blowout jets; instead, the jet itself may have gained the twist of the flux rope(s) through reconnection. This event may represent a class of jets different from the classical quiescent or blowout jets, but to reach that conclusion, more observational and theoretical work is necessary.Comment: 12 pages, 9 figures, accepted for publication in A&

The molecular signature of the stroma response in prostate cancer-induced osteoblastic bone metastasis highlights expansion of hematopoietic and prostate epithelial stem cell niches

The reciprocal interaction between cancer cells and the tissue-specific stroma is critical for primary and metastatic tumor growth progression. Prostate cancer cells colonize preferentially bone (osteotropism), where they alter the physiological balance between osteoblast-mediated bone formation and osteoclast-mediated bone resorption, and elicit prevalently an osteoblastic response (osteoinduction). The molecular cues provided by osteoblasts for the survival and growth of bone metastatic prostate cancer cells are largely unknown. We exploited the sufficient divergence between human and mouse RNA sequences together with redefinition of highly species-specific gene arrays by computer-aided and experimental exclusion of cross-hybridizing oligonucleotide probes. This strategy allowed the dissection of the stroma (mouse) from the cancer cell (human) transcriptome in bone metastasis xenograft models of human osteoinductive prostate cancer cells (VCaP and C4-2B). As a result, we generated the osteoblastic bone metastasis-associated stroma transcriptome (OB-BMST). Subtraction of genes shared by inflammation, wound healing and desmoplastic responses, and by the tissue type-independent stroma responses to a variety of non-osteotropic and osteotropic primary cancers generated a curated gene signature ("Core" OB-BMST) putatively representing the bone marrow/bone-specific stroma response to prostate cancer-induced, osteoblastic bone metastasis. The expression pattern of three representative Core OB-BMST genes (PTN, EPHA3 and FSCN1) seems to confirm the bone specificity of this response. A robust induction of genes involved in osteogenesis and angiogenesis dominates both the OB-BMST and Core OB-BMST. This translates in an amplification of hematopoietic and, remarkably, prostate epithelial stem cell niche components that may function as a self-reinforcing bone metastatic niche providing a growth support specific for osteoinductive prostate cancer cells. The induction of this combinatorial stem cell niche is a novel mechanism that may also explain cancer cell osteotropism and local interference with hematopoiesis (myelophthisis). Accordingly, these stem cell niche components may represent innovative therapeutic targets and/or serum biomarkers in osteoblastic bone metastasis

SEEDS direct imaging of the RV-detected companion to V450 Andromedae, and characterization of the system

We report the direct imaging detection of a low-mass companion to a young, moderately active star V450 And, that was previously identified with the radial velocity method. The companion was found in high-contrast images obtained with the Subaru Telescope equipped with the HiCIAO camera and AO188 adaptive optics system. From the public ELODIE and SOPHIE archives we extracted available high-resolution spectra and radial velocity (RV) measurements, along with RVs from the Lick planet search program. We combined our multi-epoch astrometry with these archival, partially unpublished RVs, and found that the companion is a low-mass star, not a brown dwarf, as previously suggested. We found the best-fitting dynamical masses to be $m_1=1.141_{-0.091}^{+0.037}$ and $m_2=0.279^{+0.023}_{-0.020}$ M$_\odot$. We also performed spectral analysis of the SOPHIE spectra with the iSpec code. The Hipparcos time-series photometry shows a periodicity of $P=5.743$ d, which is also seen in SOPHIE spectra as an RV modulation of the star A. We interpret it as being caused by spots on the stellar surface, and the star to be rotating with the given period. From the rotation and level of activity, we found that the system is $380^{+220}_{-100}$ Myr old, consistent with an isochrone analysis ($220^{+2120}_{-90}$ Myr). This work may serve as a test case for future studies of low-mass stars, brown dwarfs and exoplanets by combination of RV and direct imaging data.Comment: 15 pages, 9 figures, 7 tables, to appear in Ap