5,277 research outputs found

    Dynamic Phase Transitions in Cell Spreading

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    We monitored isotropic spreading of mouse embryonic fibroblasts on fibronectin-coated substrates. Cell adhesion area versus time was measured via total internal reflection fluorescence microscopy. Spreading proceeds in well-defined phases. We found a power-law area growth with distinct exponents a_i in three sequential phases, which we denote basal (a_1=0.4+-0.2), continous (a_2=1.6+-0.9) and contractile (a_3=0.3+-0.2) spreading. High resolution differential interference contrast microscopy was used to characterize local membrane dynamics at the spreading front. Fourier power spectra of membrane velocity reveal the sudden development of periodic membrane retractions at the transition from continous to contractile spreading. We propose that the classification of cell spreading into phases with distinct functional characteristics and protein activity patterns serves as a paradigm for a general program of a phase classification of cellular phenotype. Biological variability is drastically reduced when only the corresponding phases are used for comparison across species/different cell lines.Comment: 4 pages, 5 figure

    Reference Distorted Prices

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    I show that when consumers (mis)perceive prices relative to reference prices, budgets turn out to be soft, prices tend to be lower and the average quality of goods sold decreases. These observations provide explanations for decentralized purchase decisions, for people being happy with a purchase even when they have paid their evaluation, and for why trade might affect high quality local firms 'unfairly'

    The freshwater crayfish Austropotamobius pallipes in South Tyrol. Heritage species and bioindicator

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    Rapid decline of crayfish in European freshwaters and continuing threat necessitate integrated actions in conservation and management of native crayfish populations. Besides biological reasons (diseases, plague), the impact of toxic and harmful substances (fertilisers, herbicides) or wastewater effluents, habitat alteration or fragmentation have been responsible for their decline in some regions. The same is true for the region of South Tyrol, where compared to previous investigations, only 10 of a former total of 15 crayfish locations in the water bodies could be affirmed. Although two new populations of the non-indigenous Astacus astacus were detected, the native Austropotamobius pallipes continues to decline. While many investigations have focused accurately on causal coherences for the decline of native populations, the properties of crayfish facilitate to reverse the situation. In a few examples, the potential of Austropotamobius pallipes, the native crayfish in South Tyrol, as “surrogate species” for effective biological conservation is discussed. Given the various adequate attributes of freshwater crayfish as surrogate species (including indicator species, umbrella species and flagship species qualities), they may help to advance not only the crayfish situation itself but also freshwater ecosystem properties in general

    After the Standard Model: New Resonances at the LHC

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    Experiments will soon start taking data at CERN's Large Hadron Collider (LHC) with high expectations for discovery of new physics phenomena. Indeed, the LHC's unprecedented center-of-mass energy will allow the experiments to probe an energy regime where the standard model is known to break down. In this article, the experiments' capability to observe new resonances in various channels is reviewed.Comment: Preprint version of a Brief Review for Modern Physics Letters A. Changes w.r.t. the fully corrected version are smal

    Lysine Supplementation of Barley-Soybean Meal Diets for Growing Pigs

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    The lysine requirement of pigs as suggested by the National Research Council (NRC) was determined using corn-soybean meal based diets. More recent research has indicated that differences exist in the availability of lysine in different ingredients. It has been suggested that lysine in barley is less available than lysine in corn. Thus, it is possible that diets formulated with barley and soybean meal to meet the NRC\u27s suggested lysine requirement, might actually be deficient in this amino acid. This study was conducted to determine the lysine needs of pigs fed barley-soybean meal diets from approximately 45 to 75 lb

    Contribution of snowfall from diverse synoptic conditions in the Catskill/Delaware Watershed of New York State

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    Snowfall in the six basins of the Catskill/Delaware Watershed in south‐central New York State historically contributes roughly 20–30% of the water resources derived from the watershed for use in the New York City water supply. The watershed regularly experiences snowfall from three distinctive weather patterns: coastal mid‐latitude cyclones, overrunning systems, and lake‐effect or Great Lakes enhanced storms. Using synoptic weather classification techniques, these distinct regional atmospheric patterns impacting the watershed are isolated and analysed in conjunction with daily snowfall observations from 1960 to 2009 to allow the influence of each synoptic weather pattern on snowfall to be evaluated independently. Results indicate that snowfall‐producing events occur on average approximately 63 days/year, or once every 4 days during the October–May season, leading to an average of 213 cm/year of snowfall within the watershed. Snowfall from Great Lakes enhanced storms and overrunning systems contribute nearly equally to seasonal totals, representing 38 and 39%, respectively. Coastal mid‐latitude cyclones, while producing the highest amount of snowfall per event on average, contribute only 16% to the watershed average total snowfall. Predicted climate change is expected to impact snowfall differently depending on the specific atmospheric pattern producing the snow. As such, quantifying the contribution of snowfall to the watershed by synoptic pattern can inform future water management and reservoir operation practices for the New York City Water Supply Management System

    Commensurate antiferromagnetic ordering in Ba(Fe{1-x}Co{x})2As2 determined by x-ray resonant magnetic scattering at the Fe K-edge

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    We describe x-ray resonant magnetic diffraction measurements at the Fe K-edge of both the parent BaFe2As2 and superconducting Ba(Fe0.953Co0.047)2As2 compounds. From these high-resolution measurements we conclude that the magnetic structure is commensurate for both compositions. The energy spectrum of the resonant scattering is in reasonable agreement with theoretical calculations using the full-potential linear augmented plane wave method with a local density functional.Comment: 5 pages, 3 figures; accepted for publication in Phys. Rev. B Rapid Com

    Unusual temperature dependence of band dispersion in Ba(Fe(1-x)Ru(x))2As2 and its consequences for antiferromagnetic ordering

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    We have performed detailed studies of the temperature evolution of the electronic structure in Ba(Fe(1-x)Ru(x))2As2 using Angle Resolved Photoemission Spectroscopy (ARPES). Surprisingly, we find that the binding energy of both hole and electron bands changes significantly with temperature in pure and Ru substituted samples. The hole and electron pockets are well nested at low temperature in unsubstituted (BaFe2As2) samples, which likely drives the spin density wave (SDW) and resulting antiferromagnetic order. Upon warming, this nesting is degraded as the hole pocket shrinks and the electron pocket expands. Our results demonstrate that the temperature dependent nesting may play an important role in driving the antiferromagnetic/paramagnetic phase transition.Comment: 5 pages, 6 figure
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