Occurrence and fertility rates of hydatid cysts in sheep and goats slaughtered at Modjo Luna Export Slaughter House, Ethiopia

In Ethiopia very limited studies were conducted in small ruminant hydatidosis compared to cattle. A cross-sectional study was conducted at Modjo Luna Export Slaughter House from December 2009 to February 2010 to determine the prevalence and fertility of hydatid cysts. A total of 325 sheep and 440 goats were examined. Examination of lung, liver, kidney, heart and carcass was conducted following standard postmortem procedures. Fertility of hydatid cysts was tested by absence or presence of motility and staining with 0.1% aqueous eosin solution. Out of 325 sheep and 440 goats examined 25 (7.7%) sheep and 27(6.13%) goats had hydatid cysts. The prevalence was high in sheep compared to goats although the difference was not statistically significant (P > 0.05). The organ distribution of hydatid cyst in sheep was 15 (60%) in lung, 9 (36%) in liver and 1 (4%) both the liver and lungs. In goats, hydatid cysts were recovered from 19 (70%) of the lung, 5 (18.5%) of the liver, 1 (3.7%) of the kidney, 2 (7.4%) of the heart and 2 (7.4%) of the muscle. In both sheep and goats the infection was more in lungs, followed by liver. Eighty percent of the cysts found in the lung of sheep were fertile, while there was no fertile cyst detected in the lung of goats and the difference was statistically significant (P < 0.05). In Ethiopia, to break the life cycle of echinococcosis/hydatidosis, public education on habit of feeding condemned organs to dogs should be undertaken

Field investigation of anthelmintic efficacy and risk factors for anthelmintic drug resistance in sheep at Bedelle District of Oromia Region, Ethiopia

The study was conducted to investigate the status of anthelmintic (AH) efficacy and associated risk factors for AH resistance in sheep. Questionnaire surveys were undertaken to establish the AH utilization practices of sheep owners at the study area and identify risk factors. Four hundred fourteen sheep were sampled of which 180 sheep were selected based on their higher egg count for the fecal egg count reduction test (FECRT) to assess the efficacy of albendazole, tetramisole and ivermectin against gastrointestinal nematode parasites prevailing in sheep. Fecal culture and postmortem examination techniques were used to identify the species of nematode parasites prevalent before and after treatment. The results show that: 1) albendazole and tetramisole were the most frequently used AH in the area, 2) farmers get the drugs with or without prescription from various sources (10% open markets, 18% private drug stores and 72% government animal health clinics and 3) the prevalence of gastro-intestinal nematode infection in the study areas was 72%. 4) The FECRT revealed all the three tested AH were effective with egg count reduction levels of 96%, 99% and 97% respectively for albendazole, tetramisole and ivermectin. However, post-treatment fecal cultures and postmortem adult worm recovery showed that some Haemonchus contortus worms have escaped the treatments. In conclusion, no anthelmintic resistance was detected from clinical cure point of view but the population of H. contortus that has escaped the treatments deserves further scrutiny as this parasite is the most prolific and highly pathogenic in sheep.Key words: Anthelmintic efficacy, FECRT, Gastrointestinal Nematodes, Risk Factors, Sheep

Bovine cysticercosis and human taeniosis in South-west Shoa zone of Oromia Region, Ethiopia

A cross-sectional study was conducted in cattle slaughtered at Sebeta, Tulu Bolo and Weliso abattoirs in southwest shoa zone of Oromia region, Ethiopia to estimate the prevalence of bovine cystiercosis using routine meat inspection method, and questionnaire surveys were undertaken to assess the status of taeniosis and associated risk factors in human in these towns. Accordingly, out of 1216 carcasses examined, 4.6 % were found infected with Cysticercus bovis. Among the positive cases for C. bovis, 39.3 % were viable and 60.7% were non-viable cysts while it was more prevalent in the heart and tongue (39.3% and 30.4%, respectively) than in the diaphragm and liver. Out of 392 respondents, 55.1% had contracted T. saginata at least once in the past years. The prevalence was significantly higher in adults (> 20 years) than youngsters (< 20 years) (P<0.001), in male than females (P=0.046), in Christian than Muslim community (P=0.011), in butchers and abattoir workers than in other occupation (P<0.001), in illiterate than in literate and university graduates (P=0.001) and in raw meat consumers than in others (P<0.01. In conclusion, bovine cysticercosis caused by C. bovis and associated human taeniosis are important problems in the study areas. Improvement in meat inspection procedures and sanitary conditions in the study areas are needed.Key words: Cysticercosis, Cattle, Human, Taeniosis, Ethiopia

Review and synthesis of a walking machine (Robot) leg mechanism

A walking machine (robot) is a type of locomotion that operates by means of legs and/or wheels on rough terrain or flat surface. The performance of legged machines is greater than wheeled or tracked walking machines on an unstructured terrain. These types of machines are used for data collections in a variety of areas such as large agricultural sector, dangerous and rescue areas for a human. The leg mechanism of a walking machine has a different joint in which a number of motors are used to actuate all degrees of freedom of the legs. In the synthesis of walking machine reported in this article, the leg mechanism is developed using integration of linkages to reduce the complexity of the design and it enables the robot to walk on a rough terrain. The dimensional synthesis is carried out analytically to develop a parametric equation and the geometry of the developed leg mechanism is modelled. The mechanism used is found effective for rough terrain areas because it is capable to walk on terrain of different amplitudes due to surface roughness and aerodynamics.publishedVersio

Kinematic Modeling and Analysis of a Walking Machine (Robot) Leg Mechanism on a Rough Terrain

Many manmade machines and mechanisms including robots function based on the concept of nature-inspired design so that they can perform their intended duties by mimicking the working mechanisms of animals and insects. Accordingly, walking machines (robots) use wheels and tracks to cross rough terrain efficiently and in a stable way than more conventional robots. Legged walking robots in particular get a discontinuous contact with the ground that provides them the capability to select tractions such that obstacles or holes are escaped. This article reports a study conducted on kinematic modelling and analysis of a walking machine (robot) leg mechanism that can operate on rough terrain. Its kinematic mechanisms is analyzed using the Denavit-Hartenberg (DH) convention approach. Symbolic computations are also implemented to parametrically optimize the motion parameters of the robot leg mechanism. The equation of motion is derived from the dynamic analysis using the Euler-Lagrange method which involves kinetic and potential energy expressions. In order to validate the performance of the robot leg mechanism and motion behaviors, kinematic motion analysis in SolidWorks and MATLAB are used. The leg mechanism used is effective for rough terrain areas because it is capable of walking on terrain with different amplitudes due to surface toughness and aerodynamics.publishedVersio

Comparative clinico-pathological observations in young Zebu (Bos indicus) cattle experimentally infected with Trypanosoma vivax isolates from tsetse infested and non-tsetse infested areas of Northwest Ethiopia

BACKGROUND: The Northwest region of Ethiopia is affected by both tsetse and non-tsetse transmitted trypanosomosis with a huge impact on livestock productivity. The objective of this experimental study was to determine clinical and pathological findings in young Zebu cattle experimentally infected with Trypanosoma vivax isolates from tsetse infested and non-tsetse infested areas of Northwest Ethiopia. A total of 18 cattle (Bos indicus) aged between 6 and 12 months, purchased from a trypanosome-free and confirmed to be trypanosome negative divided into three groups of six animals were used. Animals in the first two groups (Group TT: tsetse infested isolate infected and Group NT: non-tsetse infested isolate infected) received 2 mL of infected blood from donor animals at 10(6) trypanosomes/mL, and the remaining group was non-infected control (NIC). Each group was observed for a period of eight consecutive weeks, daily for clinical signs and once per week for parasitaemia. Postmortem examinations were done on euthanized animals, and tissue samples were taken for histopathological analysis. RESULTS: The prepatent period of the disease was earlier in the NT group 6 days post infection (dpi) than TT group 12 dpi. The infection was characterized by reduced feed intake, intermittent pyrexia and parasitaemia, enlarged lymph nodes, lacrimation, reduced feed intake and emaciation. Less frequently diarrhea, oedema and nervous signs were observed in both groups of infected animals. At necropsy, infected animals showed enlarged spleen, enlarged lymph nodes, pneumonic and emphysematous lung, enlarged liver, and haemorrhages on the brain and intestine. Histopathological analysis revealed lymphoid hyperplasia of the spleen, necrosis of the liver, encephalitis and hyperplasia of lymph nodes. CONCLUSION: Trpanosoma vivax isolates from both tsetse infested and non-tsetse areas showed a variety of virulence factors leading to the development of acute clinical signs, gross and histopathological lesions. However, the parasitaemia and clinical signs appeared earlier in the NT compared to TT infected groups

Tobacco advertising, promotion, and sponsorship (TAPS) in Ethiopia: a scoping review and narrative synthesis

# Background Tobacco advertising, promotion and sponsorship (TAPS) has been shown to increase tobacco use in both adults and young people. In Ethiopia, TAPS is recognised as a top priority for the government, and all tobacco advertising, promotion, and sponsorship forms are prohibited. There is recognition that there are gaps in the evidence needed to inform policy and practice on TAPS, but the extent and nature of these gaps have not been explored. This review was aimed at understanding the extent and nature of the evidence gaps on TAPS in Ethiopia and identifying primary research priorities to inform future research direction. # Methods Systematic searches were conducted in February 2022 in the following research databases: Medline, EMBASE, and PsycInfo. Two reviewers independently screened the study reports for eligibility and extracted data from the eligible studies. The extracted data was collated and summarised descriptively and policy, practice, and research recommendations were drawn. Research topics on TAPS in Ethiopia that stakeholders perceived to be priorities for primary research were identified through a consultation workshop. # Results 579 research reports were identified, and only six studies were included in the scoping review. The included studies explored the following topics: the use of tobacco imagery in movies/films (two studies); the association between mass media exposure or home internet access and tobacco use (two studies), watching of televised football and tobacco smoking in adolescents (one study), exposure to point-of-sale advertising of tobacco products and daily occurrence of smoking or second-hand smoke exposure in the home among women (one study), and exposure to anti-smoking messages through mass media and disparities in risk perceptions across socio-economic and urban-rural subgroups (one study). None of the included studies investigated tobacco-related sponsorship. The top research priority topics identified by stakeholders in Ethiopia were: 1) barriers and facilitators to TAPS policy implementation, enforcement, and compliance monitoring; and 2) developing and testing effective, low-cost, and scalable strategies for TAPS enforcement and compliance monitoring. # Conclusions There is a need for research evidence to inform policy and practice on TAPS in Ethiopia, particularly on barriers and facilitators to TAPS policy implementation, enforcement, compliance monitoring, and effective, low-cost, and scalable strategies for TAPS enforcement and compliance monitoring

Non-communicable diseases in Ethiopia: policy and strategy gaps in the reduction of behavioral risk factors

Introduction: Non-communicable diseases (NCDs) are the leading cause of death worldwide. Over 80% of NCD deaths occur in developing countries. Four modifiable behaviors, namely tobacco use, consumption of unhealthy diet, physical inactivity, and the harmful use of alcohol, contribute to 80% of the NCD burden. Studies show that the vast majority of NCDs can be prevented through behavioral risk-reduction interventions. Properly executed, the interventions could lead to a decrease in the burden of NCDs, ranging from a 30% drop in the prevalence of cancer to a 75% reduction in cardiovascular diseases. This study examined the policy and strategy gaps in the reduction of the modifiable NCD behavioral risk factors in Ethiopia to inform and guide policy-makers and other stakeholders. Methodology: This study used a data triangulation methodology with a sequential, explanatory, mixed-method design conducted in two stages. The authors carried out quantitative analysis on the prevalence and distribution of behavioral risk factors from the Ethiopia NCD STEPwise approach to surveillance (STEPS) survey. Qualitative data on national policies and strategies complemented the analysis of the progress made so far and the existing gaps. Results and Discussion: Ethiopia has made substantial progress in responding to the NCD epidemic by developing a health sector NCD strategic action plan, generating evidence, and setting time-bound national targets on NCD behavioral risk factors. Activities mainly aimed at reducing tobacco use, such as implementation of the ratified WHO Framework Convention on Tobacco Control (FCTC), using evidence of the Global Adult Tobacco Survey (GATS), and the articulation of legislative measures are ongoing. On this paper our analysis reveals policy and strategy gaps, status in law enforcement, social mobilization, and awareness creation to reduce the major behavioral risk factors. Conclusions: NCDs share common risk factors and risk reduction strategies creates an opportunity for an effective response. However, the national response still needs more effort to have a sufficient impact on the prevention of NCDs in Ethiopia. Thus, there is an urgent need for the country to develop and implement targeted strategies for each behavioral risk factor and design functional, multisectoral coordination. There is also a need for establishing sustainable financial mechanisms, such as increasing program budgets and levying ‘sin taxes,’ to support the NCD prevention and control program. Ethiop. J. Health Dev. 2019; 33(4):259-268] Key words: NCDs, behavioral risk factors, policy, strategy, multisectoral coordination, Ethiopi

Sanitation and Health

As one article in a four-part PLoS Medicine series on water and sanitation, David Trouba and colleagues discuss the importance of improved sanitation to health and the role that the health sector can play in its advocacy