Filsafat Kebudayaan dan Sastra (dalam Perspektif Sejarah)

This paper addresses about philosophy, culture, and literature from a historical perspective. Philosophy is one of the discipline in which some interrelated disciplines of the world derive, such as education. Philosophy is concerned with how human think but not all thingking processes constitute philosophy. Indulging in philosophy implies deep and serious thingking. Cultural philosophy has uniqueness because some of its explanation involves other interrelated disciplines, such as historical philosophy, anthropology, sociology, and psychology. Cultural philosophy attempts to explain cultural element and their underlying rules, structures, and their accompanying values. Despite its emergence in the twentieth century, it has rooted since Socratic era even before. Culture is men's product during his life that does not stop there. When a culture of human being ceases to develop at certain point, it will become a civilization. Contemporary culture is influenced by rapid development and modern man is well aware of it. Culture constitutes a literary work of an individual and the object of a literary work concerns culture and social life of a community. A Literary work is never created from void

Regression Depth and Center Points

We show that, for any set of n points in d dimensions, there exists a hyperplane with regression depth at least ceiling(n/(d+1)). as had been conjectured by Rousseeuw and Hubert. Dually, for any arrangement of n hyperplanes in d dimensions there exists a point that cannot escape to infinity without crossing at least ceiling(n/(d+1)) hyperplanes. We also apply our approach to related questions on the existence of partitions of the data into subsets such that a common plane has nonzero regression depth in each subset, and to the computational complexity of regression depth problems.Comment: 14 pages, 3 figure

Simple ultraviolet-based soft-lithography process for fabrication of low-loss polymer polysiloxanes-based waveguides

A simple ultraviolet (UV)-based soft-lithography process is used for fabrication of polymer polysiloxanes (PSQ-L) waveguides. The imprint process is first done on the cladding PSQ-LL layer and is followed by a spin-coating step to fill the imprinted features with core PSQ-LH layer material. The optical loss of the straight PSQ-L waveguides is characterised by the Fabry-Perot method for the first time. Even with non-polished facet of the waveguide, the Fabry-Perot resonance spectrum is obtained. An upper limit scattering loss of the waveguide is extracted to be less than 0.8 +/- 0.2 dB/cm for TE mode and 1.3 +/- 0.2 dB/cm for TM mode at 1550 nm. The fully transferred pattern and low scattering loss proves it to be an effective way to replicate low-loss polymer PSQ-L-based waveguides

Exploring Oxidation in the Remote Free Troposphere: Insights from Atmospheric Tomography (ATom)

Earth's atmosphere oxidizes the greenhouse gas methane and other gases, thus determining their lifetimes and oxidation products. Much of this oxidation occurs in the remote, relatively clean free troposphere above the planetary boundary layer, where the oxidation chemistry is thought to be much simpler and better understood than it is in urban regions or forests. The NASA airborne Atmospheric Tomography study (ATom) was designed to produce cross sections of the detailed atmospheric composition in the remote atmosphere over the Pacific and Atlantic Oceans during four seasons. As part of the extensive ATom data set, measurements of the atmosphere's primary oxidant, hydroxyl (OH), and hydroperoxyl (HO₂) are compared to a photochemical box model to test the oxidation chemistry. Generally, observed and modeled median OH and HO₂ agree to with combined uncertainties at the 2σ confidence level, which is ~±40%. For some seasons, this agreement is within ~±20% below 6 km altitude. While this test finds no significant differences, OH observations increasingly exceeded modeled values at altitudes above 8 km, becoming ~35% greater, which is near the combined uncertainties. Measurement uncertainty and possible unknown measurement errors complicate tests for unknown chemistry or incorrect reaction rate coefficients that would substantially affect the OH and HO₂ abundances. Future analysis of detailed comparisons may yield additional discrepancies that are masked in the median values

A Chandra X-Ray Survey of Ultraluminous Infrared Galaxies

We present results from Chandra observations of 14 ultraluminous infrared galaxies (ULIRGs; log(L_IR/L_Sun) >= 12) with redshifts between 0.04 and 0.16. The goals of the observations were to investigate any correlation between infrared color or luminosity and the properties of the X-ray emission and to attempt to determine whether these objects are powered by starbursts or active galactic nuclei (AGNs). The sample contains approximately the same number of high and low luminosity objects and ``warm'' and ``cool'' ULIRGs. All 14 galaxies were detected by Chandra. Our analysis shows that the X-ray emission of the two Seyfert 1 galaxies in our sample are dominated by AGN. The remaining 12 sources are too faint for conventional spectral fitting to be applicable. Hardness ratios were used to estimate the spectral properties of these faint sources. The photon indices for our sample plus the Chandra-observed sample from Ptak et al.(2003) peak in the range of 1.0-1.5, consistent with expectations for X-ray binaries in a starburst, an absorbed AGN, or hot bremsstrahlung from a starburst or AGN. The values of photon index for the objects in our sample classified as Seyferts (type 1 or 2) are larger than 2, while those classified as HII regions or LINERs tend to be less than 2. The hard X-ray to far-infrared ratios for the 12 weak sources are similar to those of starbursts, but we cannot rule out the possibility of absorbed, possibly Compton-thick, AGNs in some of these objects. Two of these faint sources were found to have X-ray counterparts to their double optical and infrared nuclei.Comment: 40 pages, 5 tables, 14 figures, accepted by Ap

Metabolism of ticagrelor in patients with acute coronary syndromes.

© The Author(s) 2018Ticagrelor is a state-of-the-art antiplatelet agent used for the treatment of patients with acute coronary syndromes (ACS). Unlike remaining oral P2Y12 receptor inhibitors ticagrelor does not require metabolic activation to exert its antiplatelet action. Still, ticagrelor is extensively metabolized by hepatic CYP3A enzymes, and AR-C124910XX is its only active metabolite. A post hoc analysis of patient-level (n = 117) pharmacokinetic data pooled from two prospective studies was performed to identify clinical characteristics affecting the degree of AR-C124910XX formation during the first six hours after 180 mg ticagrelor loading dose in the setting of ACS. Both linear and multiple regression analyses indicated that ACS patients presenting with ST-elevation myocardial infarction or suffering from diabetes mellitus are more likely to have decreased rate of ticagrelor metabolism during the acute phase of ACS. Administration of morphine during ACS was found to negatively influence transformation of ticagrelor into AR-C124910XX when assessed with linear regression analysis, but not with multiple regression analysis. On the other hand, smoking appears to increase the degree of ticagrelor transformation in ACS patients. Mechanisms underlying our findings and their clinical significance warrant further research.Peer reviewedFinal Published versio

Impact of flood disasters on Taiwan in the last quarter century

Copyright © Springer 2006. The final publication is available at Springer via http://dx.doi.org/10.1007/s11069-005-4667-7The increasing natural disasters, especially floods during the last quarter century, are raising the economic losses in Taiwan. The most severe hazard in Taiwan is flooding induced by typhoons and storms in summer and autumn. By comparing the rivers around the world, the ones in Taiwan have the steepest slopes, the largest discharge per unit drainage area, and the shortest time of concentrations. Rapid urbanization without proper land uses managements usually worsen the flood problems. Consequently, flood hazards mitigation has become the most essential task for Taiwan to deal with. Although the government keeps improving flood defense structures, the flood damage grows continuously. In this article, possible flood mitigation strategies are identified for coping with complex environmental and social decisions with flood risk involved.National Science and Technology Center for Disaster ReductionNational Science Council, RO