Quark Hadron Phase Transition and Hybrid Stars

We investigate the properties of hybrid stars consisting of quark matter in the core and hadron matter in outer region. The hadronic and quark matter equations of state are calculated by using nonlinear Walecka model and chiral colour dielectric (CCD) model respectively. We find that the phase transition from hadron to quark matter is possible in a narrow range of the parameters of nonlinear Walecka and CCD models. The transition is strong or weak first order depending on the parameters used. The EOS thus obtained, is used to study the properties of hybrid stars. We find that the calculated hybrid star properties are similar to those of pure neutron stars.Comment: 25 pages in LaTex and 9 figures available on request, IP/BBSR/94-3

A methodology to compile multi-hazard interrelationships in a data-scarce setting: an application to Kathmandu Valley, Nepal

This paper introduces a multifaceted methodology to identify and compile single natural hazards and multi-hazard interrelationships within the context of data-scarce urban settings, exemplified by Kathmandu Valley, Nepal. This approach integrates (i) five blended types of evidence to support a more nuanced and holistic understanding of a hazardscape where data are scarce and (ii) a 2-hour stakeholder workshop with seven participants to provide greater context to the hazards, consider their impacts through the co-production of multi-hazard interrelationship scenarios, and how this methodology could support more people-centred disaster risk reduction (DRR) strategies. We use blended evidence types, including academic literature, grey literature, media, databases, and social media, to systematically search for exemplars of single hazards and multi-hazard interrelationships that have influenced or could potentially influence Kathmandu Valley. We collated 58 sources of evidence for single hazards and 21 sources of evidence for multi-hazard interrelationships. Using these sources, our study identified 21 single hazard types across six hazard groups (geophysical, hydrological, shallow Earth processes, atmospheric, biophysical, and space/celestial hazards) and 83 multi-hazard interrelationships (12 that have direct case study evidence of previous influence in Kathmandu Valley) that might influence Kathmandu Valley. These exemplars are collated into two databases that accompany this paper. We supplement these exemplars with multi-hazard interrelationship scenarios and multi-hazard impacts developed by stakeholders engaged in DRR research and practice in Kathmandu Valley. The results illustrate the complexity of the hazard landscape, with many single hazards and multi-hazard interrelationships potentially influencing Kathmandu Valley. The research emphasises the importance of inclusive DRR strategies that recognise disaggregated impacts experienced by different social groups. This knowledge can inform the development of dynamic risk scenarios in planning and civil protection, thus strengthening multi-hazard approaches to DRR in “Global South” urban areas such as Kathmandu Valley

Multigene phylogeny and mating tests reveal three cryptic species related to Calonectria pauciramosa

Calonectria pauciramosa is a pathogen of numerous plant hosts worldwide. Recent studies have indicated that it included cryptic species, some of which are identified in this study. Isolates from various geographical origins were collected and compared based on morphology, DNA sequence data of the ß-tubulin, histone H3 and translation elongation factor-1 regions and mating compatibility. Comparisons of the DNA sequence data and mating compatibility revealed three new species. These included Ca. colombiana sp. nov. from Colombia, Ca. polizzii sp. nov. from Italy and Ca. zuluensis sp. nov. from South Africa, all of which had distinguishing morphological features. Based on DNA sequence data, Ca. brasiliensis is also elevated to species leve

Enhanced nociception in angelman syndrome model mice

Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by mutation or deletion of the maternal UBE3A allele. The maternal UBE3A allele is expressed in nearly all neurons of the brain and spinal cord, whereas the paternal UBE3A allele is repressed by an extremely long antisense transcript (UBE3A-ATS). Little is known about expression of UBE3A in the peripheral nervous system, where loss of maternal UBE3A might contribute to AS phenotypes. Here we sought to examine maternal and paternal Ube3a expression in DRGs neurons and to evaluate whether nociceptive responses were affected in AS model mice (global deletion of maternal Ube3a allele; Ube3am+/p+). We found that most large-diameter proprioceptive and mechanosensitive DRG neurons expressed maternal Ube3a and paternal Ube3a-ATS. In contrast, most small-diameter neurons expressed Ube3a biallelically and had low to undetectable levels of Ube3a-ATS. Analysis of single-cell DRG transcriptomes further suggested that Ube3a is expressed monoallelically in myelinated large-diameter neurons and biallelically in unmyelinated small-diameter neurons. Behavioral responses to some noxious thermal and mechanical stimuli were enhanced in male and female AS model mice; however, nociceptive responses were not altered by the conditional deletion of maternal Ube3a in the DRG. These data suggest that the enhanced nociceptive responses in AS model mice are due to loss of maternal Ube3a in the central, but not peripheral, nervous system. Our study provides new insights into sensory processing deficits associated with AS

Empirical approach to the analysis of university student absenteeism. Proposal of a questionnaire for students to evaluate the possible causes

Works on student absenteeism in the universities have not been preferential for the authors in the field of educational research. Usually, what has been made is an approach to the available absenteeism data as an intervening variable or as a variable characteristic of the educational process, but not as a dependent variable in the strict sense of the term. In this work, we intend to make an empirical approach to the possible reasons of student absenteeism. There is a double point of view: the students" and the professors"; the reasons that justify it according to its protagonists are studied. This paper focuses on the six university degrees taught at the School of Economy and Business of the University of Barcelona (Facultat d"Economia i Empresa de la Universitat de Barcelona). An"ad-hoc" questionnaire has been prepared and the opinions of 1,162 undergraduates have been analyzed. The reasons given by each population differ in hierarchy and motivations

Emission from the D1D5 CFT

It is believed that the D1D5 brane system is described by an 'orbifold CFT' at a special point in moduli space. We first develop a general formulation relating amplitudes in a d-dimensional CFT to absorption/emission of quanta from flat infinity. We then construct the D1D5 vertex operators for minimally coupled scalars in supergravity, and use these to compute the CFT amplitude for emission from a state carrying a single excitation. Using spectral flow we relate this process to one where we have emission from a highly excited initial state. In each case the radiation rate is found to agree with the radiation found in the gravity dual.Comment: 49 pages, latex, 6 figures; v2: reformatted for JHEP, corrected typos, and added reference

Social and scientific motivations to move beyond groups in allele frequencies: The TOPMed experience

For the genomics community, allele frequencies within defined groups (or “strata”) are useful across multiple research and clinical contexts. Benefits include allowing researchers to identify populations for replication or “look up” studies, enabling researchers to compare population-specific frequencies to validate findings, and facilitating assessment of variant pathogenicity in clinical contexts. However, there are potential concerns with stratified allele frequencies. These include potential re-identification (determining whether or not an individual participated in a given research study based on allele frequencies and individual-level genetic data), harm from associating stigmatizing variants with specific groups, potential reification of race as a biological rather than a socio-political category, and whether presenting stratified frequencies—and the downstream applications that this presentation enables—is consistent with participants’ informed consents. The NHLBI Trans-Omics for Precision Medicine (TOPMed) program considered the scientific and social implications of different approaches for adding stratified frequencies to the TOPMed BRAVO (Browse All Variants Online) variant server. We recommend a novel approach of presenting ancestry-specific allele frequencies using a statistical method based upon local genetic ancestry inference. Notably, this approach does not require grouping individuals by either predominant global ancestry or race/ethnicity and, therefore, mitigates re-identification and other concerns as the mixture distribution of ancestral allele frequencies varies across the genome. Here we describe our considerations and approach, which can assist other genomics research programs facing similar issues of how to define and present stratified frequencies in publicly available variant databases

Absolute Proper Motions to B~22.5: IV. Faint, Low Velocity White Dwarfs and the White Dwarf Population Density Law

The reduced proper motion diagram (RPMD) for a complete sample of faint stars with high accuracy proper motions in the North Galactic Pole field SA57 is investigated. Eight stars with very large reduced proper motions are identified as faint white dwarf candidates. We discriminate these white dwarf candidates from the several times more numerous QSOs based on proper motion and variability. We discuss the implausibility that these stars could be any kind of survey contaminant. If {\it bona fide} white dwarfs, the eight candidates found here represent a portion of the white dwarf population hitherto uninvestigated by previous surveys by virtue of the faint magnitudes and low proper motions. The newly discovered stars suggest a disk white dwarf scaleheight larger than the values of 250-350 pc typically assumed in assessments of the local white dwarf density. Both a <V/V_{max}> and a more complex maximum likelihood analysis of the spatial distribution of our likely thin disk white dwarfs yield scaleheights of 400-600 pc while at the same time give a reasonable match to the local white dwarf volume density found in other surveys. Our results could have interesting implications for white dwarfs as potential MACHO objects. We can place some direct constraints (albeit weak ones) on the contribution of halo white dwarfs to the dark matter of the Galaxy. Moreover, the elevated scale height that we measure for the thin disk could alter the interpretation of microlensing results to the extent of making white dwarfs untenable as the dominant MACHO contributor. (Abridged)Comment: 38 pages, 5 figures, to appear in April Ap