102 research outputs found

    A Sarawak experience on the use of IPC ID PEP regimen in patients bitten by laboratory confirmed rabies animals

    Get PDF
    On 1st July 2017, rabies outbreak was declared in the state of Sarawak, which is located in the Borneo Island following the deaths of 3 children due to human rabies infection. Rabies has the highest case fatality rate but is highly preventable through prompt and effective post-exposure prophylaxis (PEP)

    FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium

    Get PDF
    Background:Breast cancer is one of the most common malignancies in women. Genome-wide association studies have identified FGFR2 as a breast cancer susceptibility gene. Common variation in other fibroblast growth factor (FGF) receptors might also modify risk. We tested this hypothesis by studying genotyped single-nucleotide polymorphisms (SNPs) and imputed SNPs in FGFR1, FGFR3, FGFR4 and FGFRL1 in the Breast Cancer Association Consortium. Methods:Data were combined from 49 studies, including 53 835 cases and 50 156 controls, of which 89 050 (46 450 cases and 42 600 controls) were of European ancestry, 12 893 (6269 cases and 6624 controls) of Asian and 2048 (1116 cases and 932 controls) of African ancestry. Associations with risk of breast cancer, overall and by disease sub-type, were assessed using unconditional logistic regression. Results:Little evidence of association with breast cancer risk was observed for SNPs in the FGF receptor genes. The strongest evidence in European women was for rs743682 in FGFR3; the estimated per-allele odds ratio was 1.05 (95 confidence interval=1.02-1.09, P=0.0020), which is substantially lower than that observed for SNPs in FGFR2. Conclusion:Our results suggest that common variants in the other FGF receptors are not associated with risk of breast cancer to the degree observed for FGFR2. © 2014 Cancer Research UK

    Middle managers' response to change from like oraganizations in Britain and Singapore A comparative study

    No full text
    SIGLEAvailable from British Library Document Supply Centre- DSC:D172568 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

    Determination of stress-strain relationship of sheet metal under biaxial tension

    No full text
    Experimental Techniques17232-35EXPT

    Do Microglial Cells Have a Neuroprotective Function?

    No full text
    Journal of Brain Research383309-31

    Macrophage and microglial cell response after common peroneal nerve cut and crush in C57BL/6J mice

    No full text
    10.1006/neur.1996.0010Neurodegeneration5173-80NEUR

    Nitrergic, peptidergic and substance P innervation of the chick thymus.

    No full text
    Journal für Hirnforschung384553-56

    Motoneuronal death without expression of NADPH-diaphorase activity after sciatic nerve cut in 5-day-old mice

    No full text
    10.1016/S0006-8993(96)00755-XBrain Research7331125-128BRRE
    corecore